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Accession number;05A0468418
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| Title;Blood Pressure Management in Patients of Acute Intracerebral Hematoma-Effectiveness of Antihypertensive Drug Administration via a Nasogastric Tube Once a Day- |
| Author;
KUROKAWA YASUTAKA
(Asahikawanoshinkeigekabyoin Noshinkeigeka)
ISHIZAKI ERI
(Asahikawanoshinkeigekabyoin Shinkeinaika)
OKAZAKI HIROBUMI
(Asahikawanoshinkeigekabyoin Yakuzaibu)
INABA KEN'ICHI
(Asahikawanoshinkeigekabyoin Noshinkeigeka)
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Journal Title;Japanese Journal of Intensive Care Medicine
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Journal Code:Z0581B
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ISSN:0389-1194
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VOL.29;NO.3;PAGE.221-226(2005)
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| Figure&Table&Reference;FIG.1, TBL.2, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A common treatment in a case immediately after intracranial bleeding is the administration of antihypertensive drugs via an intravenous route. However, these kinds of drugs sometimes require a long duration of administration with increasing amounts in order to obtain an optimum reduction of blood pressure. Moreover, oral tablets are rarely given in the acute phase of intracranial bleeding, because the patients frequently suffer from vomiting and dysphagia. Atelec (cilnidipine), a tablet known as a long acting calcium antagonist, was used in 20 intracranial hematoma cases to obtain a rapid and sufficient reduction of blood pressure and also to reduce the amount of intravenously administered drugs. The tablet was crushed into powder, then administered via a nasogastric tube immediately after the intensive care unit (ICU) admission. The powdered drug was given once a day every morning. Although some other drugs were administered at the same time, blood pressure significantly decreased 4 hours after the ICU admission, and every day compared to the initial value upon ICU admission. The intracranial hematoma never enlarged in all 20 cases. Initial tachycardia was significantly improved and heart rate remained within the normal range. The period of combined intravenous continuous administration of antihypertensive drugs such as nitroglycerine, nicardipine and diltiazem could be shortened by 3 days. Cilnidipine administration once a day used as a crushed powder via a nasogastric tube immediately after admission was thought to be an easy and effective way to decline raised blood pressure in patients of acute intracranial hematoma. (author abst.) |
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