Mechanism to make abnormal value. 1. Enzyme examination outlier and anomaly case 3. CK anomaly.

Accession number;05A0323284
Title;Mechanism to make abnormal value. 1. Enzyme examination outlier and anomaly case 3. CK anomaly.
Author; KANEMITSU FUSAE (Kurashiki Central Hospital, JPN)
Journal Title;Modern Medical Laboratory
Journal Code:Z0084B
ISSN:0301-2611
VOL.33;NO.3;PAGE.260-262(2005)
Figure&Table&Reference;TBL.2, REF.11
Pub. Country;Japan
Language;Japanese
Abstract;The creatine kinase (CK) is a dimer which consists of each subunit of skeletal muscle type and brain type, and congenital and acquired heteromorphic CKs are added to 4 kinds of typical isoenzymes, which is called CK anomaly (I). There are macroscopic CK, CK-M subunit mutation, CK-M subunit coloboma in I. In addition, there are type 1 (CK-Igs complex) and type 2 (Mi-CK octamer) in macroscopic CK. Each I is explained. The serum ratio may be too high, disease state and total serums CK activity may be dissociated and it may be detected as an abnormality on the zymogram when the serum CK-MB activity is measured in the immunity inhibitation method.