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Accession number;05A0562668
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| Title;Cardiac Resynchronization Therapy |
| Author;
MURATA KAZUYA
(Yamaguchidai Daigakuin'igakukeikenkyuka Kikanbyotainaikagaku)
MATSUZAKI MASUNORI
(Yamaguchidai Daigakuin'igakukeikenkyuka Kikanbyotainaikagaku)
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Journal Title;Japanese Journal of Intensive Care Medicine
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Journal Code:Z0581B
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ISSN:0389-1194
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VOL.29;NO.4;PAGE.247-256(2005)
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| Figure&Table&Reference;FIG.14, REF.19 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Many patients with medically-refractory severe heart failure have interventricular and intraventricular conduction delays that cause delayed activation of the lateral wall of the left ventricle (LV). This delayed activation leads to ventricular dyssynchrony, which decreases LV ejection fraction and worsens LV hemodynamic parameters. By placing a pacing lead through the coronary sinus to a lateral or posterolateral branch, the LV can be paced simultaneously or near-simultaneously with pacing from the right ventricle, leading to resynchronization of the ventricles. New York Heart Association functional class, exercise tolerance, quality of life, mitral regurgitation and LV ejection fraction have all been shown to improve with CRT. Recently, tissue Doppler imaging (TDI) has been introduced to evaluate dyssynchrony noninvasively. Many studies reported that TDI is a useful echocardiographic method to predict improvement LV dyssynchrony, a reverse remodeling and gain in ejection fraction. (author abst.) |
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