Drug Therapy for Exacerbations of Heart Failure

Accession number;05A0562672
Title;Drug Therapy for Exacerbations of Heart Failure
Author; AKINO MASATOSHI (Graduate School of Medicine, Hokkaido Univ., JPN) TSUTSUI HIROYUKI (Graduate School of Medicine, Hokkaido Univ., JPN)
Journal Title;Japanese Journal of Intensive Care Medicine
Journal Code:Z0581B
ISSN:0389-1194
VOL.29;NO.4;PAGE.285-292(2005)
Figure&Table&Reference;FIG.2, TBL.2, REF.7
Pub. Country;Japan
Language;Japanese
Abstract;Heart failure is a disorder in which the heart pumps blood inadequately, leading to reduced blood flow, congestion of peripheral tissues, and other changes that may further worsen heart failure. Heart failure can occur in people of any age. However, it is much more common among older people, because elderly people have risk factors for heart disease (such as coronary artery disease, hypertension, and a cardiomyopathy). For exacerbations of heart failure, the diuretics are most commonly used. Loop diuretics, furosemide, are most commonly used on a long-term basis, but in an emergency, they are very effective when given intravenously. Catecholamines are more effective for hypotension and shock. Carperitide are preferred for severe heart failure. Temporary partial or complete mechanical circulatory support may be an option for severe heart failure patients who have not responded to drug therapy. (author abst.)