Antibacterial activitiy of doripenem against .BETA.-lactamase-producing strains
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Accession number;05A0663310
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| Title;Antibacterial activitiy of doripenem against .BETA.-lactamase-producing strains |
| Author;
OKAMOTO RYOICHI
(School of Medicine, Kitasato Univ., JPN)
NAKANO RYUICHI
(School of Medicine, Kitasato Univ., JPN)
SATO YUKO
(School of Medicine, Kitasato Univ., JPN)
INOUE MATSUHISA
(School of Medicine, Kitasato Univ., JPN)
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Journal Title;Japanese Journal of Chemotherapy
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Journal Code:F0608A
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ISSN:1340-7007
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VOL.53;NO.Supplement 1;PAGE.47-51(2005)
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| Figure&Table&Reference;FIG.1, TBL.2, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We studied the in vitro antibacterial activity of doripenem (DRPM), a novel carbapenem, compared to imipenem, cefotaxime, ceftazidime, and cefepime, against .BETA.-lactamase-producing bacteria. DRPM was active against class A strains, including extended-apectrum .BETA.-lactamase (ESBL), and against class C and D producers, but not against class B. DRPM activity against .BETA.-lactamase producers was 2-4 times stronger than that of IPM. (author abst.) |
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