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Accession number;05A0714524
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| Title;Time-resolved X-ray crystallographic analysis on tropinone reductase-II using Laue diffraction method |
| Author;
YAMASHITA ATSUKO
(Inst. Physical and Chemical Res., JPN)
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Journal Title;Seikagaku
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Journal Code:G0184A
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ISSN:0037-1017
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VOL.77;NO.7;PAGE.649-655(2005)
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| Figure&Table&Reference;FIG.3, REF.15 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;When a protein functions, time-dependently changing phenomena occur with some actions. It is important to clarify the structure by grasping specific state where a protein actually functions in order to truly understand the phenomena. Usual crystal structure analysis, however, can obtain only spatiotemporally averaged image of all molecules in a crystal. Time-resolved X-ray crystallogrphic analysis can fill the gap. This article briefly introduces its techniques and advantages, and describes authors' research on obtaining pre-reactive enzyme structure by using one of the techniques,Laue diffraction method. |
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