The Effects of a Functional Ingredient in Meat (L-carnitine) on Skeletal Muscle Energy Metabolism
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Accession number;05A1044302
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| Title;The Effects of a Functional Ingredient in Meat (L-carnitine) on Skeletal Muscle Energy Metabolism |
| Author;
SAKO TAKAYUKI
(Japan Women's Univ.)
HAMAOKA TAKAFUMI
(National Inst. Fitness and Sports in Kanoya, JPN)
NAKADE KOJI
(Ito Ham Foods Inc., JPN)
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Journal Title;Shokuniku ni kansuru Josei Kenkyu Chosa Seika Hokokusho
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Journal Code:X0296A
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ISSN:
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VOL.23;NO.;PAGE.269-271(2005)
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| Figure&Table&Reference;REF.4 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The purpose of this study was to investigate the effects of a 30-day L-carnitine (Car) supplementation on lipid metabolism and body composition in highly trained rowers. We tested 8 male subjects (20.6 yrs, 179.0 cm height, and 71.0 kg on average) for changes in body composition (body fat and thigh muscle cross-sectional area), plasma lipid metabolism, pulmonary oxidative metabolism at rest, and during exercise before and after supplementation. The study was performed after having obtained informed consent from all subjects and designed in a controlled double-blind cross-over manner. Subjects ingested 2.0 g of Car or an iso-caloric placebo daily for 30 days with a 30-day washout period in between ingestion periods. At the start and end of each 30-day ingestion period a series of bicycle exercise protocols were performed in the following order: 35% of maximal oxygen consumption (VO2max) for 8 minutes, 80% VO2max for 30 minutes, 60 minutes rest, 35% VO2max for 8 minutes, and 110% VO2max until exhaustion. During this time blood pressure, heart rate, oxygen consumption, respiratory exchange ratio (R) were recorded. In addition, the blood plasma concentrations of total Car, free Car, acyl Car, free fatty acids (FFA), triglycerides, lactic acid and glucose were measured. We found a significant increase in total Car (from 56.1 to 68.6 .MU.mol/l) and free Car (from 48.2 to 56.7 .MU.mol/l) after Car supplementation. The increases in total and free Car after exercise at 80% VO2max were significantly attenuated after supplementation (66.6 and 44.4 .MU.mol/l respectively) compared to the placebo (51.5 and 35.8 .MU.mol/l respectively). R was significantly lower during exercise at both 35% VO2max and 80% VO2max after Car supplementation. No change was found in any indicators for body composition in both treatments.... (author abst.) |
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