HPLC Retention Behaviors of Poly-aromatic-hydrocarbones on Cu(II)-octabromotetrakis(4-carboxyphenyl)porphine Derivatives-Immobilized Aminopropyl Silica Gels in Polar and Non-Polar Eluents
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Accession number;06A0025407
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| Title;HPLC Retention Behaviors of Poly-aromatic-hydrocarbones on Cu(II)-octabromotetrakis(4-carboxyphenyl)porphine Derivatives-Immobilized Aminopropyl Silica Gels in Polar and Non-Polar Eluents |
| Author;
MIFUNE MASAKI
(Dep. Of Pharmaceutical Sciences, Graduate School Of Medicine And Dentistry And Pharmaceutical Sciences, Okayama Univ.)
KAWATA KENJI
(Dep. Of Pharmaceutical Chemistry, Graduate School Of Natural Sci. And Technol., Okayama Univ.)
TANAKA KURUMI
(Dep. Of Pharmaceutical Chemistry, Graduate School Of Natural Sci. And Technol., Okayama Univ.)
KITAMURA YOUJI
(Dep. Of Pharmaceutical Sciences, Graduate School Of Medicine And Dentistry And Pharmaceutical Sciences, Okayama Univ.)
TSUKAMOTO IKUKO
(Fac. Of Medicine, Kagawa Univ.)
SAITO MADOKA
(Dep. Of Pharmaceutical Chemistry, Graduate School Of Natural Sci. And Technol., Okayama Univ.)
SAITO MADOKA
(Fac. Of Medicine, Kagawa Univ.)
HAGINAKA JUN
(Fac. Of Pharmaceutical Sciences, Mukogawa Women's Univ.)
SAITO YUTAKA
(Dep. Of Pharmaceutical Sciences, Graduate School Of Medicine And Dentistry And Pharmaceutical Sciences, Okayama Univ.)
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Journal Title;Chem Pharm Bull
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Journal Code:G0504A
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ISSN:0009-2363
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VOL.54;NO.1;PAGE.94-98 (J-STAGE)(2006)
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| Figure&Table&Reference;FIG.9, TBL.1, REF.24 |
| Pub. Country;Japan |
| Language;English |
| Abstract;As one of approaches of developing novel HPLC stationary phases, we prepared Cu-octabromotetrakis(4-carboxyphenyl)porphine derivative-immobilized silica gels (Cu-OBTCPPD), and evaluated the availability of the resultant Cu-OBTCPPD as a stationary phase for separation of poly-aromatic-hydrocarbons (PAHs) and their related compounds. A Cu-OBTCPPD column was revealed to have an ability to separate simple PAHs and be useful as a stationary phase in both polar and non-polar eluents. The retention property of the Cu-OBTCPPD column was evaluated in various comparative experiments using commercially available columns. In comparison with 2-(1-pyrenyl)ethyl dimetylsilyl silica gel column (PYE column) regarding the retention behavior for PAHs etc., the Cu-OBTCPPD column showed stronger interactions involving .PI. electron in non-polar eluent than PYE column. In comparison with a pentabromobenzyloxy propylsilyl silica gel column (PBB column) regarding the influence of bromination, the Cu-OBTCPPD column was affected differently from the PBB column. In comparison with nitrophenylethyl silica gel column (NPE column) regarding the retention behavior for compounds having a dipole in a non-polar eluent, the Cu-OBTCPPD column showed electrostatic interactions such as dipole-dipole interaction equivalent to or larger than the NPE column. (Author abst.) |
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