Iridoids and Sesquiterpenoids with NGF-Potentiating Activity from the Rhizomes and Roots of Valeriana fauriei
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Accession number;06A0025415
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| Title;Iridoids and Sesquiterpenoids with NGF-Potentiating Activity from the Rhizomes and Roots of Valeriana fauriei |
| Author;
GUO YUANQIANG
(Dep. Of Pharmaceutical Molecular Biology, Graduate School Of Pharmaceutical Sciences, Tohoku Univ.)
XU JING
(Res. Dep. Of Natural Medicine, Shenyang Pharmaceutical Univ.)
LI YUSHAN
(Res. Dep. Of Natural Medicine, Shenyang Pharmaceutical Univ.)
WATANABE RYUICHI
(Lab. Of Bioorganic Chemistry,, Graduate School Of Life Sciences, Tohoku Univ.)
OSHIMA YASUKATSU
(Lab. Of Bioorganic Chemistry,, Graduate School Of Life Sciences, Tohoku Univ.)
YAMAKUNI TOHRU
(Dep. Of Pharmaceutical Molecular Biology, Graduate School Of Pharmaceutical Sciences, Tohoku Univ.)
OHIZUMI YASUSHI
(Dep. Of Pharmaceutical Molecular Biology, Graduate School Of Pharmaceutical Sciences, Tohoku Univ.)
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Journal Title;Chem Pharm Bull
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Journal Code:G0504A
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ISSN:0009-2363
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VOL.54;NO.1;PAGE.123-125 (J-STAGE)(2006)
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| Figure&Table&Reference;FIG.2, TBL.2, REF.13 |
| Pub. Country;Japan |
| Language;English |
| Abstract;A new iridoid glycoside, 10-isovaleryl kanokoside C (1), and a new sesquiterpene (2) together with two known compounds (3, 4) were isolated from the rhizomes and roots of Valeriana fauriei. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2 and 4 showed enhancing activity of nerve growth factor (NGF)-induced neurite outgrowth in PC 12D cells. (Author abst.) |
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