Tissue-Engineered Osteogenic Materials for Dental Implants: Clinical Results from Germany and Japan

Accession number;06A0032847
Title;Tissue-Engineered Osteogenic Materials for Dental Implants: Clinical Results from Germany and Japan
Author; HIBI HIDEHARU (Nagoya Univ. School Of Medicine, Nagoya, Jpn) YAMADA YOICHI (Nagoya Univ. School Of Medicine, Nagoya, Jpn) UEDA MINORU (Nagoya Univ. School Of Medicine, Nagoya, Jpn) UEDA MINORU (Nagoya Univ. Graduate School Of Medicine, Nagoya, Jpn) UEDA MINORU (Univ. Tokyo, Tokyo, Jpn) SCHMELZEISEN RAINER (Univ. Hospital Freiburg, Freiburg, Deu)
Journal Title;Int Med J
Journal Code:L4914A
ISSN:1341-2051
VOL.12;NO.4;PAGE.243-245(2005)
Figure&Table&Reference;FIG.2, TBL.1, REF.5
Pub. Country;Japan
Language;English
Abstract;Objective: This report introduces two new types of tissue-engineered graft materials for bone regeneration and elucidates their respective characteristics. Design: Clinical trial study. Materials and Methods: Two materials were used: (1) a gel containing culture-expanded and differentiated mesenchymal stem cells and platelet-rich plasma, and (2) polymerized fleeces containing osteoprogenitor cells derived from periosteum. Materials 1 and 2 were applied to 6 and 17 cavities using the maxillary sinus elevation technique, respectively. Results: All the materials transformed into bony tissue in 3-6 postoperative months, but some of the fleece material in one sinus cavity was removed due to infection. Conclusion: Both of the materials offer good osteogenic potential. (author abst.)