Fluctuation and Clinical Significance of Blood .ALPHA.1-Acid Glycoprotein in Dogs with Multicentric Lymphoma

Accession number;06A0120742
Title;Fluctuation and Clinical Significance of Blood .ALPHA.1-Acid Glycoprotein in Dogs with Multicentric Lymphoma
Author; ISHIKAWA KATSUYUKI (Ishikawadobutsubyoin(nagoyashi)) MORITA YASUNORI (Aichiken) WADA ATSUSHI (Aichiken) TOYOSHIMA HIROAKI (Aichiken) HARA SHIN'ICHIRO (Nagoyashi) YUKI MASASHI (Nagoyashi)
Journal Title;Journal of the Japan Veterinary Medical Association
Journal Code:Y0220A
ISSN:0446-6454
VOL.59;NO.2;PAGE.126-130(2006)
Figure&Table&Reference;FIG.4, TBL.2, REF.10
Pub. Country;Japan
Language;Japanese
Abstract;Blood samples (serum or plasma) from ten dogs with multicentric lymphoma (ML) were tested for initial blood .ALPHA.1-acid glycoprotein(.ALPHA.1AG). Four of five dogs with ML that initially had normal or slightly elevated .ALPHA.1-acid glycoprotein (.ALPHA.1AG) (<900.MU.g/ml) had complete remission without recurrence. In contrast, four of five dogs with ML that initially had .ALPHA.1AG>900.MU.g/ml had significantly shorter complete remission times and unstable clinical condition. These findings suggest that serum .ALPHA.1AG level can be used as a prognostic marker in dogs with ML. (author abst.)