Immunohistochemical Investigation of Six Cases of Swine Lymphoma

Accession number;06A0120744
Title;Immunohistochemical Investigation of Six Cases of Swine Lymphoma
Author; HOSHINO MINORU (Niigatashishokunikueiken) OGURO MASAFUMI (Niigatashishokunikueiken) TANABE JUN'ICHI (Niigatashishokunikueiken) TSUJISAWA MASATO (Niigatashihokensho) TOSAKA YUICHI (Niigatashihokensho) SHIBAHARA TOMOYUKI (National Inst. Animal Health, JPN) KADOTA KOICHI (National Inst. Animal Health, JPN)
Journal Title;Journal of the Japan Veterinary Medical Association
Journal Code:Y0220A
ISSN:0446-6454
VOL.59;NO.2;PAGE.135-139(2006)
Figure&Table&Reference;FIG.11, TBL.2, REF.21
Pub. Country;Japan
Language;Japanese
Abstract;Six cases of swine lymphoma were investigated histologically and immunohistochemically, and were classified based on the new WHO classification for human lymphoid malignancies. CD79a was expressed in five cases, three of which were diagnosed as diffuse large B-cell lymphoma (cases 2-4). Cytoplasmic immunoglobulin (Ig) was detected in a few cells. The remaining B-cell cases were a precursor B lymphoblastic lymphoma (case 1) and a composite lymphoma (a combination of lymphoplasmacytic lymphoma and immunoblastic lymphoma) (case 5), and were characterized by positive reactivity for terminal deoxynucleotidyl transferase (TdT) and the production of IgM (.LAMBDA.), respectively. In a peripheral T-cell lymphoma (case 6), the neoplastic cells showed CD3.EPSILON. positivity, but did not express TdT. These six lymphomas resembled the human counterpart neoplasms in their morphology. (author abst.)