Histiocytic Sarcoma in an Aged Cow, Showing Marked Erythrophagia
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Accession number;06A0194771
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| Title;Histiocytic Sarcoma in an Aged Cow, Showing Marked Erythrophagia |
| Author;
OBA TAKEMI
(Toyamakenshokunikukensasho)
IMAI SHIGENORI
(Toyamakenshokunikukensasho)
YAMAMOTO SHINJI
(Kushirokachikuhoken'eisho)
SHIBAHARA TOMOYUKI
(NARO, National Inst. Animal Health, JPN)
KADOTA KOICHI
(NARO, National Inst. Animal Health, JPN)
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.59;NO.3;PAGE.203-207(2006)
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| Figure&Table&Reference;FIG.7, REF.19 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Histiocytic sarcoma was observed in a 12-year-old Japanese Black cow. Neoplastic lesions were detected in the bone marrow, and the spleen and lymph nodes were enlarged. Hemorrhagic foci were seen in a number of organs. Examination of the blood showed a leukopenia and a depressed platelet count. Histologically, neoplastic cells resembling mature histiocytes revealed sheet-like or diffuse growth pattern in the bone marrow, spleen and lymph nodes, and many showed erythrophagia in areas of severe hemorrhage. Immuno-positive reactions to lysozyme and HAM56 indicated that this neoplasm originated from histiocytes and was distinguishable from other lymphohematopoietic neoplasms with erythrophagocytosis. (author abst.) |
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