Regenerative medicine and aesthetic medicine: from "apparent beauty" to "creative beauty"
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Accession number;06A0281876
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| Title;Regenerative medicine and aesthetic medicine: from "apparent beauty" to "creative beauty" |
| Author;
KUROYANAGI YOSHIMITSU
(Kitasato Univ., JPN)
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Journal Title;Aesthetic Dermatol
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Journal Code:L5200A
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ISSN:1341-5530
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VOL.16;NO.1;PAGE.10-17(2006)
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| Figure&Table&Reference;FIG.8, REF.10 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Regenerating Medical Millennium Projects of the Ministry of Health, Labor and Welfare have been conducted in Japan between 2000 and 2005. Allogeneic cultured dermal substitutes (CDS) were transported from R&D Center for Artificial Skin, School of Allied Health Sciences, Kitasato University to 31 hospitals across Japan. In 404 clinical cases, 92% of various wounds including burns and intractable skin ulcers were evaluated as achieving good or excellent results. CDS is prepared by incorporating fibroblasts into a spongy matrix composed of hyaluronic acid and collagen. CDS is able to release various types of growth factors that are essential for wound healing. Furthermore, the matrix components, hyaluronic acid and collagen are also able to promote wound healing. Recently, the implantation of cultured fibroblasts or chondrocytes has been tried in the field of aesthetic medicine. As one of the established treatments, chemical peeling has been widely employed. Since chemical peeling is a superficial chemical burn, an appropriate treatment is required after neutralization. More desirable clinical result may be obtained using the same materials as a matrix of CDS. Highly purified hyaluronic acid and medical-grade collagen are essential for wound healing. The concept of wound healing is a prerequisite for both regenerative medicine and aesthetic medicine. Chemical peeling may become a successful treatment to realize "creative beauty" not "apparent beauty" if excellent materials are employed to promote wound healing after neutralization. (author abst.) |
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