A Case of Severe Glaucoma with Pseudopemphigoid Successfully Treated by Filtration Surgery Using Amniotic Membrane

Accession number;06A0264967
Title;A Case of Severe Glaucoma with Pseudopemphigoid Successfully Treated by Filtration Surgery Using Amniotic Membrane
Author; HINO KEIKO (Kyoto Prefect. Univ. of Med. Fac. of Med.) MORI KAZUHIKO (Kyoto Prefect. Univ. of Med. Fac. of Med.) SOTOZONO CHIE (Kyoto Prefect. Univ. of Med. Fac. of Med.) IKEDA YOKO (Kyoto Prefect. Univ. of Med. Fac. of Med.) NARUSE SHIGETA (Kyoto Prefect. Univ. of Med. Fac. of Med.) ISHIBASHI TAKESHI (Kyoto Prefect. Univ. of Med. Fac. of Med.) NANJO YUKAKO (Kyoto Prefect. Univ. of Med. Fac. of Med.) KINOSHITA SHIGERU (Kyoto Prefect. Univ. of Med. Fac. of Med.)
Journal Title;Journal of Japanese Ophthalmological Society
Journal Code:Z0666A
ISSN:0029-0203
VOL.110;NO.4;PAGE.312-317(2006)
Figure&Table&Reference;FIG.5, REF.28
Pub. Country;Japan
Language;Japanese
Abstract;Background: It is necessary to decrease topical anti-glaucoma medication for severe glaucoma with pseudopemphigoid caused by anti-glaucoma eye drops. Glaucoma filtrating surgery is often needed instead of medication, but the prognosis is poor because it induces scar fomation and makes the filtrating bleb vanish. Case: An 85-year-old male patient with exfoliation syndrome had twice undergone glaucoma surgery about ten years previously. His intra-ocular pressure (IOP) was high despite topical anti-glaucoma medication. At the first examination in our hospital, he had severe superficial punctate keratopathy, blephariticshortening and symblepharon, and we therefore diagnosed severe pseudopemphigoid induced by anti-glaucoma eye drops. Because his IOP could not be controlled by topical and general medication, we conducted a glaucoma filtrating operation using amniotic membrane. Conclusion: The administration of oral anti-inflammatory drugs before and after surgery and the use of amniotic membrane prevented post-operative scar formation and the progress of symblepharon, resulting in the successful control of IOP after surgery. (author abst.)