Future of Neurotherapeutics-Regenerative Medicine-
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Accession number;06A0292920
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| Title;Future of Neurotherapeutics-Regenerative Medicine- |
| Author;
KATAYAMA YASUO
(Nippon Medical School, JPN)
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Journal Title;Neurological Therapeutics
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Journal Code:X0110A
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ISSN:0916-8443
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VOL.23;NO.1;PAGE.5-9(2006)
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| Figure&Table&Reference;REF.8 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Recently, in the field of intractable neuropathy and various neurological disorders whose treatments are believed to be difficult, elucidating their etiologies have progressed by advanced molecular biology. Their treatment methods have been developing with a rapid advance of diagnostic equipments and an advance of molecular engineering. However, for cerebral ischemic diseases and degenerative diseases represented by amyotrophic lateral sclerosis, Parkinson's disease, and Alzheimer's disease whose radical treatment is currently absent, only the treatments to prevent the exacerbation of the symptoms are applied. As for cerebral ischemia, although a tissue plasminogen activator (t-PA), a thrombolytic agent, has been commercialized, its indications are several percents of whole patients with cerebral infarction. Thus, majority of the patients suffer from critical sequelas, including paralysis, speech disturbance, aphasia, and intellectual dysfunction. In such current situation, regenerative medicine whose studies have been rapidly developed recently is considered to become one of important medical cares in the 21st century, in which neurological diseases can be expected to become curable diseases from incurable diseases. In this paper, the perspective of regenerative medicine of neurological disease, especially cerebral ischemia, Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS), was described. (author abst.) |
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