What Does the '13'C02 Excretion Curve Represent in the '13'C-octanoate Gastric Emptying Breath Test?
|
Accession number;06A0338490
|
| Title;What Does the '13'C02 Excretion Curve Represent in the '13'C-octanoate Gastric Emptying Breath Test? |
| Author;
SANAKA MASAKI
(Teikyo Univ., Sch. of Med.)
YAMAMOTO TAKATSUGU
(Teikyo Univ., Sch. of Med.)
KUYAMA YASUSHI
(Teikyo Univ., Sch. of Med.)
|
Journal Title;Ther Res
|
Journal Code:Y0681A
|
ISSN:0289-8020
|
|
VOL.27;NO.4;PAGE.689-692(2006)
|
| Figure&Table&Reference;FIG.5, REF.4 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Recent studies suggested that a pattern of gastric emptying (GE) on a minute-by-minute basis (gastric velocity) is more closely related to the genesis of dyspeptic symptoms than an overall GE rate. Considering that, in the '13'C-octanoate breath test, the velocity is represented by the '13'C02 excretion %dose/h curve, inspection of the '13'C02 excretion curve may provide valuable information on the GE velocity pattern. This study attempted to relate the '13'C02 excretion curve to the velocity profile. The simulation study using the convolution technique has suggested that, in a typical case, 1) the ascending part of the '13'C02 excretion curve mainly reflects the velocity pattern, 2) the initial convex-up shape corresponds to the initial "unregulated" outflow, and 3) the subsequent linear increase results from the regulated emptying under the post-gastric feedback control. Visual inspection of the '13'C02 excretion curve may indicate how far the velocity profile is remote from the typical velocity pattern, providing further insight into a possible relationship between gastric motility and dyspeptic symptoms. (author abst.) |
|
|
|
Related Articles;
|
|
