Transient fall in pulmonary oxygenation soon after hyperbaric oxygenation for systemic infection

Accession number;06A0314072
Title;Transient fall in pulmonary oxygenation soon after hyperbaric oxygenation for systemic infection
Author; DOHGOMORI HIROSHI (Kagoshima Univ. Hospital) ARIKAWA KAZUHIRO (Kagoshima Univ. Hospital, Okinawa, Jpn) KANMURA YUICHI (Kagoshima Univ., Kagoshima, Jpn)
Journal Title;Med Postgrad
Journal Code:X0599A
ISSN:0285-4716
VOL.44;NO.2;PAGE.175-183(2006)
Figure&Table&Reference;FIG.3, REF.15
Pub. Country;Japan
Language;English
Abstract;We evaluated the transient disturbance in pulmonary oxygenation seen soon after administration of hyperbaric oxygenation therapy (HBOT). Nineteen patients underwent HBOT: twelve with systemic infections (group I-G) were compared (in terms of the change in pulmonary oxygenation) with seven patients with central nerve disturbance (hypoxic encephalopathy: group H-G). HBOT was performed to treat infections or ileus in I-G and to treat hypoxic encephalopathy in H-G. HBOT was performed once a day, with the number of days being decided according to the condition of each patient. Pulmonary oxygenation was measured at three time-points, one before and two after HBOT. In I-G, a significant disturbance in pulmonary oxygenation was seen soon after HBOT, but this was reversed within about 4-6 hours. However, the same disturbance was not seen in H-G. Conclusion: Our results indicate that in infected patients needing respiratory support, pulmonary oxygenation may worsen immediately after HBOT. The possible occurrence of this phenomenon needs to be considered when HBOT is performed for any patient with a severe infection and respiratory distress. (author abst.)