Clinical Evaluation of a Sunscreen Anthelios XL for Drug Induced Phototoxic Reactions

Accession number;06A0338795
Title;Clinical Evaluation of a Sunscreen Anthelios XL for Drug Induced Phototoxic Reactions
Author; NISHIGORI CHIKAKO (Kobe Univ., JPN) BITO TOSHINORI (Kobe Nishi City Hospital, JPN) ROUGIER ANDRE (La Roche-posay Pharmaceutical Lab., La Roche-posay, Fra) RICHARD ALAIN (La Roche-posay Pharmaceutical Lab., La Roche-posay, Fra)
Journal Title;Skin Research
Journal Code:Z0014C
ISSN:1347-1813
VOL.5;NO.1;PAGE.81-90(2006)
Figure&Table&Reference;FIG.5, TBL.7, REF.11
Pub. Country;Japan
Language;Japanese
Abstract;Many drugs have been incriminated in phototoxic and photoallergic responses. The responsible wave length spectrum for most of the drug induced photosensitivity falls on UVA. However, sometimes UVB or visible light is also responsible. So, in order to prevent drug-induced photosensitivity, only a highly protective UVA+UVB broad spectrum sunscreen may allow continual use. In this study, evaluation of UVA+UVB broad spectrum sunscreens are done and Antehlios XL was found to be highly protective against phototoxic reaction caused by olrugs in terms of clinical score and colorimetric measurement without any side effects. (author abst.)
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