Incidence and Risk Factors of Intraocular Pressure Elevation after Triamcinolone Acetonide Administration for Macular Disorders

Accession number;06A0350580
Title;Incidence and Risk Factors of Intraocular Pressure Elevation after Triamcinolone Acetonide Administration for Macular Disorders
Author; ITO TAKESHI (Nagoya City Univ., JPN) NOZAKI MIHO (Nagoya City Univ., JPN) OGURA YUICHIRO (Nagoya City Univ., JPN)
Journal Title;Journal of Japanese Ophthalmological Society
Journal Code:Z0666A
ISSN:0029-0203
VOL.110;NO.5;PAGE.379-383(2006)
Figure&Table&Reference;FIG.5, TBL.2, REF.19
Pub. Country;Japan
Language;Japanese
Abstract;Purpose: We investigated the incidence and risk factors of intraocular pressure(IOP) elevation following triamcinolone administration for macular disorders. Methods: Intravitreal or posterior sub-Tenon's injections of triamcinolone acetonide were conducted on 119 eyes with macular disorders. The change in IOP was followed for all cases. Risk factors for IOP elevation were examined regarding causal disease, history of vitrectomy, methods of injection, frequency of injection, refractive power, and age. Result: The difference between the mean baseline IOP (13.0.+-.2.9 mmHg) and the maximum mean IOP (21.5.+-.9.8 mmHg) was statistically significant (p<0.0001). The final mean IOP was 15.1.+-.3.6 mmHg. Forty-one eyes (34.5%) had IOP elevation over 21 mmHg during the follow-up. Fifty-nine eyes (49.6%) showed pressure elevation of over 5 mmHg. One eye (1%) required trabeculotomy to control the IOP. Risk factors for the IOP elevation included younger age, high myopia, no history of vitrectomy, and multiple injections. Conclusion: Careful follow-up of the IOP is required after triamcinolone acetonide injections. (author abst.)