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Accession number;06A0382474
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| Title;Orientations of Water Molecules Surrounding B-DNA Observed by Neutron Crystallographic Analysis |
| Author;
ARAI SHIGEKI
(Nihongensiryokukenkyuukaihatukikou)
CHATAKE TOSHIYUKI
(Chibakadai)
NIIMURA NOBUO
(Ibaraki Univ., Graduate School of Sci. and Engineering, JPN)
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Journal Title;Journal of the Crystallographic Society of Japan
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Journal Code:G0232A
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ISSN:0369-4585
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VOL.48;NO.2;PAGE.133-139(2006)
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| Figure&Table&Reference;FIG.6, TBL.1, REF.35 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;By neutron diffraction measurements of B-DNA duplex, we have succeeded in determining the D positions in 27 D2O molecules. Moreover, the complex water network in the minor groove has been observed in detail. By a combined structural analysis using X-ray and neutron data, it is clear that the spine of hydration is built up, not only by a simple hexagonal hydration pattern, but also by many other water bridges hydrogen-bonded to the DNA strands. The complexity of the hydration pattern in the minor groove is derived from an extraordinary variety of orientations displayed by the water molecules. (author abst.) |
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