The Research of the Pathogen Responsible for Pleurocybella porrigens Related Encephalopathy: Investigation of 3-Nitropropionic Acid Hypothesis

Accession number;06A0346118
Title;The Research of the Pathogen Responsible for Pleurocybella porrigens Related Encephalopathy: Investigation of 3-Nitropropionic Acid Hypothesis
Author; OBARA KOJI (Akita Univ., JPN) MUTO HAJIME (Akita Univ., JPN) ITO HIDEAKI (Akita Univ., Facutity of Engineering and Resource Sci, JPN) SATO SHIGERU (Akita Univ., JPN) GONMORI KUNIO (Hamamatsu Univ. School of Medicine, JPN) WATANABE SUMIO (Akita Univ., JPN) WATANABE SUMIO (Akita Univ., JPN) TOYOSHIMA ITARU (Akita Univ., JPN)
Journal Title;Brain Nerve
Journal Code:Z0685A
ISSN:0006-8969
VOL.58;NO.4;PAGE.311-317(2006)
Figure&Table&Reference;FIG.2, TBL.3, REF.39
Pub. Country;Japan
Language;Japanese
Abstract;Pleurocybella porrigens related encephalopathy exhibits consciousness disturbance and convulsion in the patients after taking and patients show bilateral basal ganglia lesion resulted in high mortality rate. This encephalopathy is a very similar to the moldy sugarcane encephalopathy epidemic in China in the past. We investigated the relationship between Pleurocybella porrigens related encephalopathy and 3-nitropropionic acid which had caused the moldy sugarcane encephalopathy. We have tried to detect 3-NPA in the various specimens from patients and Pleurocybella porrigens, but failed. Further examinations for elucidating the causation of Pleurocybella porrigens related encephalopathy are needed. (author abst.)
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