Genomic and Serological Characterization of Bovine Viral Diarrhea Virus Recently Isolated in Ishikawa Prefecture in Japan

Accession number;06A0372832
Title;Genomic and Serological Characterization of Bovine Viral Diarrhea Virus Recently Isolated in Ishikawa Prefecture in Japan
Author; HAYASHI MICHIKO (Shizuoka Prefect. Gov., South. Livest. Hyg. Serv. Center, JPN) MURAKAMI TOSHIAKI (Shizuoka Prefect. Gov., South. Livest. Hyg. Serv. Center, JPN) TAKAI HIKARU (Shizuoka Prefect. Gov., South. Livest. Hyg. Serv. Center, JPN) NAGAI MAKOTO (Shizuoka Prefect. Gov., North. Livest. Hyg. Serv. Center, JPN) YAMAGUCHI TOORU (Shizuoka Prefect. Gov., South. Livest. Hyg. Serv. Center, JPN) FUNAKI OSAMU (Shizuoka Prefect. Gov., South. Livest. Hyg. Serv. Center, JPN) AKASHI HIROOMI (Univ. Tokyo, Graduate School of Agricaltural and Life Sci., JPN)
Journal Title;Journal of the Japan Veterinary Medical Association
Journal Code:Y0220A
ISSN:0446-6454
VOL.59;NO.5;PAGE.320-324(2006)
Figure&Table&Reference;FIG.1, TBL.2, REF.30
Pub. Country;Japan
Language;Japanese
Abstract;During the period 1995 to 2005, a total of 32 BVDV isolates were recovered from persistently infected calves and cattle with mucosal disease in Ishikawa Prefecture. All isolates were divided on the basis of phylogenetic analysis into four subgroups. Nine out of 32 isolates (28.1%) were classified as a subtype BVDV-1a, while 17 (53.1%) were classified as BVDV-1b. The calculated antigenic similarity (R) among BVDV-1 subgroups and BVDV-2 as revealed by cross-neutralization assay showed significant antigenic differences between BVDV-1 and BVDV-2 (0.3-1.1) and within BVDV-1 subgroups (1.0-23.9). A No. 12 strain of BVDV-1a, which has been used as a parent strain of Japanese live vaccine showed R values of 0.6, 12.1, 23.9 and 10.2 when compared with BVDV-2, 1b, 1c and 1So, respectively. The data suggested that antigenically different BVDVs from the Japanese representative and the parent vaccinal strain are very widespread in Ishikawa Prefecture. (author abst.)