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Accession number;06A0372834
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| Title;Reference Ranges for Canine Serum Thyroxin and Thyrotropin Concentration Measured by Chemiluminescence Immunoassay |
| Author;
TSUCHIYA RYO
(Azabu Univ., Sch. of Vet. Med.)
KAYAMA TAKESHI
(Azabu Univ., Sch. of Vet. Med.)
ARAKAWA MAMPEI
(Azabu Univ., Sch. of Vet. Med.)
()
()
KITA HIDEHARU
(Azabu Univ., Sch. of Vet. Med.)
HISASUE MASAHARU
(Azabu Univ., Sch. of Vet. Med.)
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.59;NO.5;PAGE.331-335(2006)
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| Figure&Table&Reference;FIG.2, TBL.2, REF.21 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Reference ranges for serum thyroxin (T4) and thyrotropin (TSH) in dogs in Japan were established by measuring the total T4 and TSH concentrations in 159 healthy dogs using Chemiluminescence Enzyme Immunoassay (CLEIA) for canine samples. Reference ranges for free T4 (F-T4) in the same population were established using a Chemiluminescence Immunoassay (CLIA) system for human samples. The T4 and F-T4 data were normally distributed and TSH results followed lognormal distribution. The reference ranges were defined as the mean.+-.2SD (log transformed data were used for TSH). The ranges obtained were 0.61-3.30.MU.g/dl for T4, 0-0.50ng/ml for TSH and 0.52-1.97ng/dl for F-T4. In addition, serum T4 and TSH were measured in 33 experimental beagle dogs and 35 patient dogs with severe illnesses. The results indicated subclinical primary hypothyroidism in the beagle dogs and a high rate of euthyroid sick syndrome in the patient dogs. (author abst.) |
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