The Effect of Hydroxyurea on Secondary Polycythemia in Two Dogs with Right-To-Left Shunting Congenital Heart Disease
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Accession number;06A0372835
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| Title;The Effect of Hydroxyurea on Secondary Polycythemia in Two Dogs with Right-To-Left Shunting Congenital Heart Disease |
| Author;
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.59;NO.5;PAGE.336-338(2006)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.8 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Two dogs diagnosed with polycythemia caused by either tetralogy of Fallot or atrial septal defect associated with pulmonic arterial stenosis, respectively, were treated with an antitumor agent, hydroxyurea. The treatment caused a decrease in hematocrit values and improved clinical signs. Although mild transient leukopenia or mild alopecia in the head, trunk and extremities were observed, hydroxyurea treatment was well tolerated. Hydroxyurea treatment was effective in the management of secondary polycythemia, and may be an alternative treatment to repeated phlebotomy. (author abst.) |
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