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Accession number;06A0471974
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| Title;A Case of Pyoderma Gangrenosum with Aseptic Cervical and Mediastinal Abscesses in a Patient with MDS and Tolosa-Hunt Syndrome |
| Author;
YOSHIDA ERI
(Hyogo Prefectural Awaji Hospital, JPN)
CHIYOMARU KOJI
(Hyogo Prefectural Awaji Hospital, JPN)
FUKUDA HITOSHI
(Hyogo Prefectural Awaji Hospital, JPN)
HAMADA MAKOTO
(Hyogo Prefectural Awaji Hospital, JPN)
NOMURA TETSUHIKO
(Hyogo Prefectural Awaji Hospital, JPN)
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Journal Title;Skin Research
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Journal Code:Z0014C
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ISSN:1347-1813
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VOL.5;NO.2;PAGE.133-138(2006)
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| Figure&Table&Reference;FIG.5, TBL.1, REF.39 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We report a case of pyoderma gangrenosum (PG) with aseptic cervical and mediastinal abscesses, an unusual complication of PG. A 52-year-old Japanese woman with myelodysplastic syndrome (MDS) and Tolosa-Hunt syndrome, treated with prednisolone, developed a cervical abscess followed by a mediastinal abscess. After the drainage by thoracotomy, she developed necrotic skin lesion on her chest. The biopsy revealed massive infiltration of neutrophils in the whole dermis. The lesion turned to be sterile. We diagnosed the chest lesion was PG and presumed that cervical and mediastinal lesions were related to PG. These lesions were aggravated by G-CSF for the treatment of MDS but pulsed administration of methylprednisolone followed by oral prednisolone improved all these lesions. We summarized reports of PG cases with aseptic abscess in visceral organs. (author abst.) |
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