The treatment of the combination therapy using artificial dermis and bFGF with intractable ulcers

Accession number;06A0332359
Title;The treatment of the combination therapy using artificial dermis and bFGF with intractable ulcers
Author; SATSUKI REIKO (Fukui Prefectural Hospital, JPN) KAWAKAMI SHIGEHIKO (Kanazawa Medical Univ., School of Medicine, JPN)
Journal Title;Skin Research
Journal Code:Z0014C
ISSN:1347-1813
VOL.5;NO.Suppl.6;PAGE.46-51(2006)
Figure&Table&Reference;FIG.13, TBL.1, REF.4
Pub. Country;Japan
Language;Japanese
Abstract;Bacic fibroblast growth factor (bFGF) which is one of the growth factors gives us good useful clinical effects for skin ulcers and pressure sores. It operates on good vascularization and good granulation. In addition, we experienced that the combination therapy using bFGF and an artificial dermis can make sufficient granulation tissues in intractable ulcers with the bared bone and, further, we confirmed experimentally that the combination therapy using bFGF and an artificial dermis was effective with full-thickness skin defect to the bare cartilage in rabbits through tissue samples with H-E staining and molded blood vessels with scanning electron microscopes. It concluded that the combination therapy using bFGF and an artificial dermis was effective for intractable ulcers with the bared bone or cartilage. (author abst.)