Experimental Study on the Effects of Blood Admixture with Calcium Phosphate Cement
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Accession number;06A0557948
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| Title;Experimental Study on the Effects of Blood Admixture with Calcium Phosphate Cement |
| Author;
MUSHA YOSHIRO
(Toho Univ. School Of Medicine, Tokyo, Jpn)
UMEDA TOMOHIRO
(Sophia Univ., Tokyo, Jpn)
MIZUTANI KAZUHIRO
(Toho Univ. School Of Medicine, Tokyo, Jpn)
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Journal Title;Med Postgrad
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Journal Code:X0599A
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ISSN:0285-4716
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VOL.44;NO.3;PAGE.269-278(2006)
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| Figure&Table&Reference;FIG.9, TBL.1, REF.12 |
| Pub. Country;Japan |
| Language;English |
| Abstract;The effects of blood admixture on the physical properties of calcium phosphate cement (CPC); Biopex-R (BPR) were experimentally investigated both in vitro and in vivo. The compressibility of BPR decreased when it was mixed with blood. This was also observed even when the powder-liquid ratio (P/L ratio) was maintained constant at the time of admixture, suggesting that it was attributable not merely to a decrease in P/L ratio, but also to the direct effects of blood. In the animal experiment (Japanese white rabbits), comparisons of radiographs and histological examination taken over time revealed no changes in the control, while the sample with a larger volume of admixed blood showed clear regression of the opacity representing the hardened substance and replacement of bone for 12 weeks after the implantation. Therefore, although the compressive strength of BPR decreased with blood admixture, the efficiency of bone replacement and remodeling increased, suggesting that the development of CPC as an absorbable material for bone replacement should utilize admixed blood. (author abst.) |
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