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Accession number;06A0557953
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| Title;Relation between airway occlusion pressure and positive end-expiratory pressure in weaning from mechanical ventilation |
| Author;
DOHGOMORI HIROSHI
(Kagoshima Univ. Hospital Sakuragaoka, Kagoshima, Jpn)
ARIKAWA KAZUHIRO
(Kagoshima Univ. Hospital)
KANMURA YUICHI
(Kagoshima Univ. Fac. Medicine)
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Journal Title;Med Postgrad
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Journal Code:X0599A
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ISSN:0285-4716
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VOL.44;NO.3;PAGE.303-308(2006)
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| Figure&Table&Reference;FIG.1, TBL.7, REF.14 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Airway occlusion pressure (P0.1) is one of the indicators which can predict the outcome of weaning from a ventilator. However, there have been but few studies on the relation between P0.1 and PEEP values. Our study was designed to assess the magnitude of P0.1 at various PEEP values. Patients who underwent heart surgery or aortic grafting during cardio-pulmonary bypass were studied. A Ventilator provided a pressure support of 5-7 cmH2O during the measurement of P0.1. We increased the PEEP value from 0 to 7.5 cmH2O in 2.5 cmH2O steps and measured the P0.1 value at each setting. For this analysis, the patients are divided into those successfully weaned and those unsuccessfully weaned. The two groups differed in their mean P0.1 value at PEEP 0 and in the way in which their P0.1 values responded to increasing PEEP values. Patients who were later successfully weaned from their ventilator showed a distinct drop in their P0.1 values when PEEP was increased from 0 to 2.5 cmH2O, but their P0.1 values subsequently increased again at higher PEEP values. Patients who could not be weaned from their ventilator showed a progressive decrease in P0.1 values as their PEEP values was increased up to 7.5 cmH2O. In conclusion, the way in which P0.1 changes with increasing PEEP values seems to be predictive of the eventual outcome of weaning from mechanical ventilation. (author abst.) |
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