A Case with Cardiac Amyloidosis of which Diastolic Dysfunction Was Serially Evaluated
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Accession number;06A0673862
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| Title;A Case with Cardiac Amyloidosis of which Diastolic Dysfunction Was Serially Evaluated |
| Author;
MATSUDA ATSUSHI
(Kokusai Shinzen Sogo Byoin)
SAWANO MASATO
(Kokusai Shinzen Sogo Byoin)
YOSHIDA KEIKO
(Kokusai Shinzen Sogo Byoin)
NAKAYAMA RIICHIRO
(Kokusai Shinzen Sogo Byoin)
ARIMA MIZUHIRO
(Kokusai Shinzen Sogo Byoin)
MIYAZAKI TADASHI
(Juntendo Univ., School of Medicine, JPN)
SUZUKI HIROMASA
(Juntendo Univ., School of Medicine, JPN)
DAIDA HIROYUKI
(Juntendo Univ., School of Medicine, JPN)
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Journal Title;Ther Res
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Journal Code:Y0681A
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ISSN:0289-8020
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VOL.27;NO.8;PAGE.1502-1507(2006)
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| Figure&Table&Reference;FIG.5, TBL.1, REF.8 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A 53-year-old man, who had been seen for a few years at our hospital due to vasospastic angina pectoris and cardiac arrhythmia, came to our emergency room because of syncope. The electrocardiogram (ECG) showed complete atrioventricular block (AV block) with maximum prolonged R-R interval of 5.3 seconds. The echocardiogram (UCG) showed diffusely thickened left ventricular wall with normal systolic performance. Bence Jones protein in urine was positive. Endomyocardial biopsy from the right ventricle showed amyloid accumulation. Thus, he was diagnosed to have cardiac amyloidosis caused by multiple myeloma. We probated his past ECG series as well as UCG. The ECG findings showed gradually worsened low voltage, absent R waves in precordial leads, and left axial deviation. The past UCG revealed left ventricular hypertrophy with increased Tei-index (0.67), which was followed by shortened deceleration time. Amyloidosis, at times, causes cardiac disorder by showing AV block, myocardial hypertrophy, or heart failure due to diastolic dysfunction. Though our case, Tei-index seems to be a valuable indicator in terms of suggesting the presence of cardiac amyloidosis. (author abst.) |
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