Listeria Monocytogenes Meningoencephalitis Lacking Meningeal Signs

Accession number;06A0610704
Title;Listeria Monocytogenes Meningoencephalitis Lacking Meningeal Signs
Author; ITAYA KAZUHIRO (Japan Labour Health and Welfare Organization, Tokyo Rosai Hospital, JPN) ONO HIDEKI (Japan Labour Health and Welfare Organization, Tokyo Rosai Hospital, JPN) KAWASE YUJI (Japan Labour Health and Welfare Organization, Tokyo Rosai Hospital, JPN) NAKAJIMA MASASHI (Japan Labour Health and Welfare Organization, Tokyo Rosai Hospital, JPN)
Journal Title;Brain Nerve
Journal Code:Z0685A
ISSN:0006-8969
VOL.58;NO.7;PAGE.621-624(2006)
Figure&Table&Reference;FIG.1, REF.9
Pub. Country;Japan
Language;Japanese
Abstract;We report a fatal case of meningoencephalitis due to Listeria monocytogenes. A 74-year-old alcoholic man presented with high-grade fever lasting for four days without headache and meningeal signs. Routine blood analysis showed leukocytosis, but serum C-reactive protein (CRP) was not significantly elevated. He developed altered consciousness with focal seizure, and cerebrospinal fluid (CSF) examination showed a minor degree of pleocytosis, elevated protein, and hypoglycorrhachia. Repeated CSF examination four days later showed greater increases in cells and proteins as well as severely decreased glucose level. Bacterial culture from the initial CSF showed a growth of L. monocytogenes. Meningoencephalitis caused by L. monocytogenes may have atypical clinical and laboratory features, and should be listed in the differential diagnosis of immunocompromised or elderly patients presenting with fever of unknown origin associated with altered consciousness. (author abst.)
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