Effect of Sodium Nitroprusside on Carp Thrombocyte Aggregation

Accession number;06A0769749
Title;Effect of Sodium Nitroprusside on Carp Thrombocyte Aggregation
Author; MATSUSHITA TERUO (National Fisheries Univ., JPN) INOUE SHIN'ICHI (National Fisheries Univ., JPN) TANAKA RYUSUKE (National Fisheries Univ., JPN) KONDO MASAKAZU (National Fisheries Univ., JPN) TAKAHASHI YUKINORI (National Fisheries Univ., JPN)
Journal Title;Journal of National Fisheries University
Journal Code:F0239A
ISSN:0370-9361
VOL.54;NO.3;PAGE.77-81(2006)
Figure&Table&Reference;FIG.2, REF.23
Pub. Country;Japan
Language;Japanese
Abstract;Effect of sodium nitroprusside (SNP), a typical nitric oxide (NO) donor on the aggregation of carp (Cyprinus carpio) thrombocyte, in comparison with rat platelet, was studied by the whole blood method using an impedance aggregometer. Thrombocyte aggregation, induced in the carp by collagen, failed to be inhibited by SNP, while SNP partially but significantly inhibited collagen-induced platelet aggregation in the rat. This suggests that NO does not play an inhibitory role in the mechanism of carp thrombocyte aggregation, unlike the aggregation in rat platelets. (author abst.)