Clinical Application of Transcranial Magnetic Stimulation for the Treatment of Depression
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Accession number;06A0909593
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| Title;Clinical Application of Transcranial Magnetic Stimulation for the Treatment of Depression |
| Author;
KITO SHINSUKE
(Kyorin Univ., School of Medicine, JPN)
FUJITA KEN'ICHI
(Kyorin Univ., School of Medicine, JPN)
KOGA YOSHIHIKO
(Kyorin Univ., School of Medicine, JPN)
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Journal Title;Neurological Therapeutics
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Journal Code:X0110A
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ISSN:0916-8443
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VOL.23;NO.5;PAGE.483-487(2006)
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| Figure&Table&Reference;TBL.1, REF.24 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;There have been many studies on the clinical application of transcranial magnetic stimulation (TMS) in the field of mental diseases; especially, its treatment of depressive patients is studied the most. In the treatment of depression by repetitive TMS (rTMS), the regions to be stimulated depends on the frequency of the rTMS, and in the application of a high-frequency rTMS, the left dorsolateral prefrontal cortex is selected, and in case of a low-frequency rTMS, the right dorsolateral prefrontal cortex is selected. According to clinical findings and studies until now, more efficacious and safer parameters for the application of the rTMS have been clarified. However, the designs of these studies are different each other with respect to parameters for rTMS, methods of a sham-stimulation, subjects and others, so the effects of the treatments are different. To establish rTMS as one of treatments of depression in the near future, further knowledge is required by standardizing the parameters for the rTMS and the method of a shamstimulation in addition to clarifying the mechanism of the onset of the antidepressant effects. In this article, the authors report mainly on the relationship between the parameters of the rTMS and the effects of treatment, and the result of a randomized controlled trial (RCT). (author abst.) |
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