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Accession number;06A1040527
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| Title;The Pathogenetic Role of IgE in the Development of Atopic Dermatitis |
| Author;
SATO SHIN'ICHI
(Nagasaki Univ.)
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Journal Title;Skin Research
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Journal Code:Z0014C
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ISSN:1347-1813
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VOL.5;NO.Suppl.7;PAGE.1-4(2006)
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| Figure&Table&Reference;FIG.2, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;It has been reported that serum IgE levels are elevated in 30-40% of healthy individuals and that the early presence of elevated serum IgE does not predict the development of atopic dermatitis. Furthermore, repeated antigen application on the murine skin results in the manifestations similar to atopic dermatitis and elevation in serum IgE, suggesting that IgE production is secondary to the dermatitis. In this regard, early treatment with local steroid administration would reduce chronic inflammation and thereby inhibit IgE production. (author abst.) |
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