Prescriptions of Benzodiazepines in a University Teaching Hospital: Patient-based Data Analysis Using a Computer Ordering System
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Accession number;07A0044257
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| Title;Prescriptions of Benzodiazepines in a University Teaching Hospital: Patient-based Data Analysis Using a Computer Ordering System |
| Author;
NOMURA KYOKO
(Teikyo Univ., Fac. Medicine, JPN)
NOMURA KYOKO
(Teikyo Univ., Hospital)
NAKAO MUTSUHIRO
(Teikyo Univ., Fac. Medicine, JPN)
NAKAO MUTSUHIRO
(Teikyo Univ., Hospital)
TAKEUCHI TAKEAKI
(Teikyo Univ., Fac. Medicine, JPN)
TAKEUCHI TAKEAKI
(Teikyo Univ., Hospital)
YAMAJI KIYOHISA
(Teikyo Univ., Hospital)
SATO MIKIYA
(Teikyo Univ., Fac. Medicine, JPN)
YANO EIJI
(Teikyo Univ., Fac. Medicine, JPN)
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Journal Title;Japanese Journal of Psychosomatic Medicine
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Journal Code:Z0162B
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ISSN:0385-0307
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VOL.47;NO.1;PAGE.41-47(2007)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.22 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Objectives: Benzodiazepines are remarkably useful drugs for psychological illnesses. However, because of dependency and withdrawal symptoms, it is difficult for the patients to stop taking the medication once it is started. The purpose of the present study was to determine the tendency of benzodiazepine prescriptions at a university teaching hospital setting and clinical characteristics of patients in long-term prescription for benzodiazepines. Subjects: This cross-sectional study was performed by using data from the database of a computer ordering system at our university hospital. Subjects were 34422 outpatients (female ratio: 52%) who visited the university hospital and were prescribed some kind of drugs between July 2002 and June 2003. Method: The prevalence of patients receiving benzodiazepines was estimated and they were further categorized into two groups (a long-term group prescribed 4 months or longer, and a short-term group prescribed 3 months or shorter). Clinical characteristics were compared between the two groups including patients' sex and age, department clinics visited ('internal medicine', 'surgery', 'psychiatry', and 'others'), kind of benzodiazepines (anxiolytics and hypnotics) and their pharmacological half-life ('ultra-short', 'short', 'intermediate', 'long', and 'ultra-long'). Statistical analyses were performed based on chi-square test. In the long-term group, the patterns of prescription among department clinics from the perspective of pharmacological half-life were additionally investigated in anxiolytics and hypnotics. Results: Among the 34422 patients, 5959 patients (17%) were prescribed benzodiazepines during the study period: 4135 receiving anxiolytics and 3209 receiving hypnotics. The long-term group included 4470 patients (female 58%, mean age 59.+-.17 years) and the short-term group included 1489 patients (female 61%, mean age 50.+-.18 years).... (author abst.) |
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