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J Antibiot

Production, Isolation and Structure Determination of Novel Fluoroindolocarbazoles from Saccharothrix aerocolonigenes ATCC 39243.
Isolation, and Biological Properties of a New Cell Cycle Inhibitor, Curvularol, Isolated from Curvularia sp. RK97-F166.
New Cyclic Depsipeptide Antibiotics, Clavariopsins A and B, Produced by an Aquatic Hyphomycetes, Clavariopsis aquatica.
New Cyclic Depsipeptide Antibiotics, Clavariopsins A and B, Produced by an Aquatic Hyphomycetes, Clavariopsis aquatica.
Bioxanthracenes from the Insect Pathogenic Fungus Cordyceps pseudomilitaris BCC 1620. I. Taxonomy, Fermentation, Isolation and Antimalarial Activity.
Bioxanthracenes from the Insect Pathogenic Fungus Cordyceps pseudomilitaris BCC 1620. II. Structure Elucidation.
Design of a Novel Mammalian Screening System for the Detection of Bioavailable, Non-cytotoxic Streptogramin Antibiotics.
Extremophilic Organisms as an Unexplored Source of Antifungal Compounds.
Construction and Physiological Studies on a Stable Bioengineered Strain of Shengjimycin.
Novel Fungal Metabolites as Cell Wall Active Antifungals. Fermentation, Isolation, Physico-chemical Properties, Structure and Biological Activity.
Borrelidin Inhibits a Cyclin-dependent Kinase (CDK), Cdc28/Cln2, of Saccharomyces cerevisiae.
Identification of Four Genes from the Granaticin Biosynthetic Gene Cluster of Streptomyces violaceoruber Tue22 Involved in the Biosynthesis of L-Rhodinose.
AJI9561, a New Cytotoxic Benzoxazole Derivative Produced by Streptomyces sp.
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A Family of Depsi-peptide Fungal Metabolites, as Selective and Competitive Human Tachykinin Receptor (NK2) Antagonists. Fermentation, Isolation, PhysicQ-chemical Properties, and Biological Activity.
FR198248, a New Anti-influenza Agent Isolated from Aspergillus terreus No.13830. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities.
Studies on the Biosynthesis of Epothilones. The PKS and Epothilone C/D Monooxygenase.
Haliangicin, a Novel Antifungal Metabolite Produced by a Marine Myxobacterium. 1. Fermentation and Biological Characteristics.
Haliangicin, a Novel Antifungal Metabolite Produced by a Marine Myxobacterium. 2. Isolation and Structural Elucidation.
Glycosylative Inactivation of Chalcomycin and Tylosin by a Clinically Isolated Nocardia asteroides Strain.
Differentiating the Biosynthesis of Pseudomonic Acids A and B.
Ampullosporins B, C, D, E1, E2, E3, and E4, from Sepedonium ampullosporum HKI-0053. Structures and Biological Activities.
Cyclo (D-Pro-L-Val), a Specific .BETA.-Glucosidase Inhibitor Produced by Aspergillus sp. F70609.
UCF76 Compounds, New Inhibitors of Farnesyltransferase Produced by Steptomyces.
Phoenistatin, A New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum.
Synthesis of a New Polycyclic Quinone by Reduction of a Dihydrobenzo[a]naphthacenequinone.
Site-specific Structural Transformation of the Novel Antifungal Cycle Depsipeptide FR901469. Synthesis and Biological Activity of FR203903.
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Isolation and Structure Elucidation of Vicenistatin M, and Importance of the Vicenisamine Aminosugar for Exerting Cytotoxicity of Vicenistatin.
Cephaibols, New Peptaibol Antibiotics with Anthelmintic Properties from Acremonium tubakii DSM 12774.
Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase, Produced by Aspergillus niger FT-0554.
Collinone, a New Recombinant Angular Polyketide Antibiotic Made by an Engineered Streptomyces Strain.
Deletion of rapQONML from the Rapamycin Gene Cluster of Streptomyces hygroscopicus Gives Production of the 16-O-Desmethyl-27-desmethoxy Analog.
Studies on Anti-MRSA Parenteral Cephalosporins. III. Synthesis and Antibacterial Activity of 7.BETA.-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-alkoxyiminoacetamido]-3-[(E)-2-(1-alkylimidazo[1,2-b]pyridazinium-6-yl)thiovinyl]-3-cephem-4-carboxylates and Related Compounds.
Synthesis of 14,15-Dehydroerythromycin A Ketolides: Effects of the 13-Substituent on Erythromycin Tautomerism.
Synthesis and Biological Evaluation of Cytogenin Derivatives.
New Anti-influenza Agents, FR198248 and Its Derivatives. II. Characterization of FR198248, Its Related Compounds and Some Derivatives.
New Naphthyridinomycin-type Antibiotics, Aclidinomycins A and B, from Streptomyces halstedi.
Isolation of a New Antibiotic Oligomycin G Produced by Streptomyces sp. WK-6150.
Chemical Modification of the Eremomycin Antibiotic Formation of a Cyclic Covalent Dimer.
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Novel Macrolactins as Antibiotic Lactones from a Marine Bacterium.
New Type II Manumycins Produced by Streptomyces nodosus ssp. asukaensis and Their Biosynthesis.
Phagocytosis of Alveolar Macrophages after Conagenin Injection to Rats.
The Chemical Structure of Mumbaistatin, a Novel Glucose-6-phosphate Translocase Inhibitor Produced by Streptomyces sp. DSM 11641.
Studies on Anti-MRSA Parenteral Cephalosporins. IV. A Novel Water-soluble N-Phosphono Type Prodrug for Parenteral Administration.
Thiopeptide Non-producing Streptomyces Species Carry the tipA Gene: A Clue to Its Function.
Selective Cytotoxicity and Stereochemistry of Aspochalasin D.
Convergent Synthesis of Arisugacin Skeletons and Their Acetylcholinesterase Inhibitory Activity.
Determination of Absolute Stereochemistries of Arisugacin F and Territrem B, Novel Acetylcholinesterase Inhibitors.
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RP-1776, a Novel Cyclic Peptide Produced by Streptomyces sp., Inhibits the Binding of PDGF to the Extracellular Domain of Its Receptor.
S-15183a and b, New Sphingosine Kinase Inhibitors, Produced by a Fungus.
TMC-69, a New Antitumor Antibiotic with Cdc25A Inhibitory Activity, Produced by Chrysosporium sp. TC1068.
Streptocidins A-D, Novel Cyclic Decapeptide Antibiotics Produced by Streptomyces sp. Tue 6071. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Streptocidins A-D, Novel Cyclic Decapeptide Antibiotics Produced by Streptomyces sp. Tue 6071. II. Structure Elucidation.
TPU-0031-A and B, New Antibiotics of the Novobiocin Group Produced by Streptomyces sp. TP-A0556.
Biotransformation of Selamectin with Streptomyces lydicus SX-1298 Using a Novel Static Agar Fermentation System with Reemay Mesh.
Synthesis of Hydrophobic N'-Mono and N',N"-Double Alkylated Eremomycins Inhibiting the Transglycosylation Stage of Bacterial Cell Wall Biosynthesis.
New Cephalosporin Antibiotics with 3-Triazolylpyridiniummethyl Substituents.
Anti-angiogenic Activities of Novel Isocoumarins, AGI-7 and Sescandelin.
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Novel Reduced Benzo[j]fluoranthen-3-ones from Cladosporium cf. cladosporioides with Cytokine Production and Tyrosine Kinase Inhibitory Properties.
F13459, a New Derivative of Mycophenolic Acid. I. Taxonomy, Isolation, and Biological Properties.
F13459, a New Derivative of Mycophenolic Acid. II. Physico-chemical Properties and Structural Elucidation.
Association of Induced Disease Resistance of Rhododendron Seedlings with Inoculation of Streptomyces sp. R-5 and Treatment with Actinomycin D and Amphotericin B to the Tissue-culture Medium.
3-Keto-9-O-substituted Oxime Derivatives of 6-O-Methyl Erythromycin A Synthesis and In Vitro Activity.
New Inhibitors of 3.ALPHA.-Hydroxysteroid Dehydrogenase, 0231A and 0231B from Streptomyces sp. HKI 0231.
Benzastatins H and I, New Benzastatin Derivatives with Neuronal Cell Protecting Activity from Streptomyces nitrosporeus.
Two New Roridins Isolated from Myrothecium sp.
Epicorazine C, an Antimicrobial Metabolite from Stereum hirsutum HKI 0195.
Spirobenzofuran, a New Bioactive Metabolite from Acremonium sp. HKI 0230.
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SNF4435C and D, Novel Immunosuppressants Produced by a Strain of Streptomyces spectabilis. I. Taxonomy, Fermentation, Isolation and Biological Activities.
SNF4435C and D, Novel Immunosuppressants Produced by a Strain of Streptomyces spectabilis. II. Structure Elucidation.
Deacetylravidomycin M, a New Inhibitor of IL-4 Signal Transduction, Produced by Streptomyces sp. WK-6326. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Deacetylravidomycin M, a New Inhibitor of IL-4 Signal Transduction, Produced by Streptomyces sp. WK-6326. II. Structure Elucidation.
Cedarmycins A and B, New Antimicrobial Antibiotics from Streptomyces sp. TP-A0456.
Yokonolide A, a New Inhibitor of Auxin Signal Transduction, from Streptomyces diastatochromogenes B59.
An Efficient Screening Approach for Anti-Microcystis Compounds Based on Knowledge of Aquatic Microbial Ecosystem.
FR901469, a Novel Antifungal Antibiotic from an Unidentified Fungus No. 11243. III. Structure Determination.
Isolation and Structural Characterization of Colistin Components.
UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. VI(1). Structure-Activity Relationships of UK-2A.
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SW-163C and E, Novel Antitumor Depsipeptides Produced by Streptomyces sp. I. Taxonomy, Fermentation, Isolation and Biological Activities.
SW-163C and E, Novel Antitumor Depsipeptides Produced by Streptomyces sp. II. Structure Elucidation.
TMC-205 a New Transcriptional Up-Regulator of SV40 Promoter Produced by an Unidentified Fungus. Fermentation, Isolation, Physico-chemical Properties, Structure Determination and Biological Activities.
Cladospolide D, a New 12-Membered Macrolide Antibiotic Produced by Cladosporium sp. FT-0012.
Influence of Ancillary Genes, Encoding Aspects of Methionine Metabolism, on Tylosin Biosynthesis in Streptomyces fradiae.
Effects of Aflastatin A, an Inhibitor of Aflatoxin Production, on Aflatoxin Biosynthetic Pathway and Glucose Metabolism in Aspergillus parasiticus.
Potent Antimalarial Activities of Polyether Antibiotic, X-206.
Synthesis and Antibacterial Activity of the Tricyclic Ketolides TE-802 and Its Analogs.
New Bioactive Cyclopentenone Derivatives as Inhibitors of the IL-6 Dependent Signal Transduction.
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Cytokine Production Inhibitors Produced by a Fungus, Oidiodendron griseum.
Novel Cytokine Production Inhibitors Produced by a Basidiomycete, Marasmiellus sp.
Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. I. Production, Isolation and Biological Activity.
Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. II. Physico-chemical Properties and Structure Elucidation.
Pluraflavins, Potent Antitumor Antibiotics from Saccharothrix sp. DSM 12931.
Bagremycin A and B, Novel Antibrotics from Streptomyces sp. Tue 4128.
A Novel Assay for Fungal Ketol-isomerase Activity.
Sulphostin, a Potent Inhibitor for Dipeptidyl Peptidase IV from Streptomyces sp. MK251-43F3.
New Pentanorlanostane Derivatives, Cladosporide B-D, as Characteristic Antifungal Agents Against Aspergillus fumigatus, Isolated from Cladosporium sp.
A New Tropolone fromn the Insect Pathogenic Fungus Cordyceps sp. BCC 1681.
Structure-activity Relationship of the Antimycoplasma Anitibiotic Micacocidin. A Preliminary Study.
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Memnopeptide A, a Novel Terpene Peptide from Memnoniella with an Activating Effect on SERCA2.
A Facile and Effective Screening Method for p21WAF1 Promoter Activators from Microbial Metabolites.
Characterization of Mutants Defective in Melanogenesis and a Gene for Tyrosinase of Streptomyces griseus.
Directed Biosynthesis of New Enniatins.
New Biotransformation Products of Nemadectins.
L-2,5-Dihydrophenylalanine, an Inducer of Cathepsin-dependent Apoptosis in Human Promyelocytic Leukemia Cells (HL-60).
A Simple Screening System for Anti-HIV Drugs: Syncytium Formation Assay Using T-Cell Line Tropic and Macrophage Tropic HIV env Expressing Cell Lines. Establishment and Validation.
YUA001, a Novel Aldose Reductase Inhibitor Isolated from Alkalophilic Corynebacterium sp. YUA25. II. Chemical Modification and Biological Activity.
Quinolactacins A1 and A2, New Acetylcholinesterase Inhibitors from Penicillium citrinum.
Chrolactomycin, a Novel Antitumor Antibiotic Produced by Streptomyces sp.
New Immunosuppressive Activity of Dykellic Acid.
Novel Amidine Conjugates of the Ornithine Moiety of the Macrocyclic Antifungal Lipopeptidolactone FR901469.
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SW-163A and B, Novel Immunosuppressants Produced by Streptomyces sp.
Isolation and Structural Determination of Phepropeptins A, B, C, and D, New Proteasome Inhibitors, Produced by Streptomyces sp.
Chlorogentisylquinone, a New Neutral Sphingomyelinase Inhibitor, Produced by a Marine Fungus.
Bisabosquals, Novel Squalene Synthase Inhibitors. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Bisabosquals, Novel Squalene Synthase Inhibitors. II. Physico-chemical Properties and Structure Elucidation.
CJ-15,183, a New Inhibitor of Squalene Synthase Produced by a Fungus, Aspergillus aculeatus.
A New Antibiotic CJ-17,665 from Aspergillus ochraceus.
New Pyrrolizidinone Antibiotics CJ-16,264 and CJ-16,367.
Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp. I. Taxonomy, Fermentation and Biological Activity.
Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp. II. Isolation and Structure Elucidation.
The Production of Novel Sordarin Analogues by Biotransformation.
Effect of Solvents on Bioconversion of Penicillin G to Deacetoxycephalosporin G.
Selective Production of Staplabin and SMTPs in Cultures of Stachybotrys microspora Fed with Precursor Amines.
Mutagenesis of the Rapamycin Producer Streptomyces hygroscopicus FC904.
L 970843 and L 970844, Two New Antifungal Metabolites from an Unidentified Fungal Species HIL Y-903146.
Regulation of Tumor Necrosis Factor-.ALPHA. Production by a Fungal Metabolite, PR 1388.
Roridin L, M and Verrucarin M, New Macrocyclic Trichothecene Group Antitumor Antibiotics, from Myrothecium verrucaria.
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Tyropeptins A and B, New Proteasome Inhibitors Produced by Kitasatospora sp. MK993-dF2. I. Taxonomy, Isolation, Physico-chemical Properties and Biological Activities.
Tyropeptins A and B, New Proteasome Inhibitors Produced by Kitasatospora sp. MK993-dF2. II. Structure Determination and Synthesis.
Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neuronal Cells from Excitotoxicity. I. Fermentation, Isolation, Physico-chemical Properties and Biological Activity.
Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity. II. Structure Determination.
CJ-13,981 and CJ-13,982, New Squalene Synthase Inhibitors.
CJ-19,784, a New Antifungal Agent from a Fungus, Acanthostigmella sp.
Goadsporin, a Chemical Substance which Promotes Secondary Metabolism and Morphogenesis in Streptomycetes. I. Purification and Characterization.
Goadsporin, a Chemical Substance which Promotes Secondary Metabolism and Morphogenesis in Streptomycetes. II. Structure Determination.
Tripropeptins, Novel Antimicrobial Agents Produced by Lysobacter sp. I. Taxonomy, Isolation and Biological Activities.
CJ-15,801, a Novel Antibiotic from a Fungus, Seimatosporium sp.
Biosynthesis of the Thiazolylpeptide Antibiotic GE2270.
Some Biological and Biochemical Activities of Resormycin, a Novel Herbicidal Antibiotic.
Synthesis and Antibacterial Activity of Novel 1.BETA.-Methyl Carbapenems with Cycloalkylamine Moiety at the C-2 Position.
A New Trichostatin Derivative, Trichostatin RK, from Streptomyces sp. RK98-A74.
Structure of Sch 528647: A New Antitumor Antibiotic Related to Fumagillin.
MF-EA-705.ALPHA. & MF-EA-705.BETA., New Metabolites from Microbial Fermentation of a Streptomyces sp.
Migrastatin, a Novel 14-Membered Ring Macrolide, Inhibits Anchorage-independent Growth of Human Small Cell Lung Carcinoma Ms-1 Cells.
Syntheses of 2-Aryliminooxazolidine Derivatives as Trehalase Inhibitors.
NK30424A and B, Novel Inhibitors of Lipopolysaccharide-induced Tumour Necrosis Factor Alpha Production, Produced by Streptomyces sp. NA30424.