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J Antibiot

Isolation of a Novel Cyclic Hexadepsipeptide Pipalamycin from Streptomyces as an Apoptosis-inducing Agent.
CJ-15,696 and Its Analogs, New Furopyridine Antibiotics from the Fungus Cladobotryum varium: Fermentation, Isolation, Structural Elucidation, Biotransformation and Antibacterial Activities.
A Novel Antibiotic CJ-17,572 from a Fungus, Pezicula sp.
CJ-21,058, a New SecA Inhibitor Isolated from a Fungus.
YM-181741, a Novel Benz[a]anthraquinone Antibiotic with Anti-Helicobacter pylori Activity from Streptomyces sp.
Biologically Active Secondary Metabolites from the Ascomycete A111-95. 1. Production, Isolation and Biological Activities.
Studies on the Biosynthesis of Epothilones: Hydroxylation of Epo A and B to Epothilones E and F.
Biosynthesis of Hibarimicins. I. 13C-Labeling Experiments.
Biosynthesis of Hibarimicins. II. Elucidation of Biosynthetic Pathway by Cosynthesis Using Blocked Mutants.
Biosynthesis of Hibarimicins. III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants.
SNF4435C and D, Novel Immunosuppressants Produced by a Strain of Streptomyces spectabilis. III. Immunosuppressive Efficacy.
Enhancement of Fibrinolytic Activity of U937 Cells by Malformin A1.
Antibiotic A10255 (Thioplabin) Enhances Fibrin Binding and Activation of Plasminogen.
Synthesis and Activities of Bactobolin Derivatives Having New Functionality at C-3.
Inhibition of Recombinant Sphingosine Kinases by Novel Inhibitors of Microbial Origin, F-12509A and B-5354c.
Biologically Active Secondary Metabolites from the Ascomycete A111-95 2. Structure Elucidation.
Distribution of Polyketide Synthase Genes in Bacterial Populations.
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CJ-21,164, a New D-Glucose-6-phosphate Phosphohydrolase Inhibitor Produced by a Fungus Chloridium sp.
Kosinostatin, a Quinocycline Antibiotic with Antitumor Activity from Micromonospora sp. TP-A0468.
NMR Analysis of Quinocycline Antibiotics: Structure Determination of Kosinostatin, an Antitumor Substance from Micromonospora sp. TP-A0468.
Migrastatin and a New Compound, Isomigrastatin, from Streptomyces platensis.
Absolute Stereostructures of Cell Adhesion Inhibitors, Macrosphelides H and L, from Periconia byssoides OUPS-N133.
Stachyflin and Acetylstachyflin, Novel Anti-influenza A Virus Substances, Produced by Stachybotrys sp. RF-7260. I. Isolation, Structure Elucidation and Biological Activities.
Stachyflin and Acetylstachyflin, Novel Anti-influenza A Virus Substances, Produced by Stachybotrys sp. RF-7260. II. Synthesis and Preliminary Structure-Activity Relationships of Stachyflin Derivatives.
Funicone-related Compounds, Potentiators of Antifungal Miconazole Activity, Produced by Talaromyces flavus FKI-0076.
Preparation and Cytotoxic Activity of Some New Rhodomycin Derivatives Bearing Modifications in the Sugar Moiety.
Total Synthesis of Novel Antibiotics Pyloricidin A, B and C and Their Application in the Study of Pyloricidin Derivatives.
Trienomycin G, a New Inhibitor of Nitric Oxide Production in Microglia Cells, from Streptomyces sp. 91614.
Sterins A and B, New Antioxidative Compounds from Stereum hirsutum.
Phenylpyropene C, a New Inhibitor of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium griseofulvum F1959.
Structure of Sch 419560, a Novel .ALPHA.-Pyrone Antibiotic Produced by Pseudomonas fluorescens.
Antifungal Mechanism of FK463 against Candida albicans and Aspergillus fumigatus.
Production of Selenohomocystine as an Antibiotic by a Marine Bacillus sp. No. 14 with Selenomethionine Resistance.
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Novel Stachyflin Derivatives from Stachybotrys sp. RF-7260 Fermentation, Isolation, Structure Elucidation and Biological Activities.
Watasemycins A and B, New Antibiotics Produced by Streptomyces sp. TP-A0597.
A New Screening Method for Antimitotic Substances and Isolation of Glycolipids as Stimulators of Tubulin Polymerization from Okinawan Sponge Pseudoceratina sp.
Biosynthesis of the Trehalase Inhibitor Trehazolin.
Effects of Hibarimicins and Hibarimicin-Related Compounds Produced by Microbispora on v-Src Kinase Activity and Growth and Differentiation of Human Myeloid Leukemia HL-60 Cells.
A Pathway-specific Cell Based Screening System to Detect Bacterial Cell Wall Inhibitors.
Identification of Compounds That Inhibit Late Steps of Peptidoglycan Synthesis in Bacteria.
Propeptin, a New Inhibitor of Prolyl Endopeptidase Produced by Microbispora. II. Determination of Chemical Structure.
Simocyclinones, Novel Cytostatic Angucyclinone Antibiotics Produced by Streptomyces antibioticus Tue 6040. II. Structure Elucidation and Biosynthesis.
New Amidino-benzimidazolyl Derivatives of Tylosin and Desmycosin.
UK-2A, B, C, and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. VII. Membrane Injury Induced by C9-UK-2A, a Derivative of UK-2A, in Rhodotorula mucilaginosa IFO 0001.
Synthesis and Anti-Helicobacter pylori Activity of Pyloricidin Derivatives. I. Structure-activity Relationships on the Terminal Peptidic Moiety.
Oxidative Modification of NK30424A and B Enhance Inhibitory Effect on Lipopolysaccharide-induced Tumour Necrosis Factor-.ALPHA. Promoter Activity.
Biosynthesis of Simocyclinone D8 in an 18O2-rich Atmosphere.
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Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells. I. Screening, Taxonomy, Fermentation and Biological Activities.
Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells. II. Isolation, Physicochemical Properties and Structural Elucidation.
Anicequol, a Novel Inhibitor for Anchorage-independent Growth of Tumor Cells from Penicillium aurantiogriseum Dierckx TP-F0213.
Neosordarin and Hydroxysordarin, Two New Antifungal Agents from Sordaria araneosa.
Radamycin, a Novel Thiopeptide Produced by Streptomyces sp. RSP9. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Radamycin, a Novel Thiopeptide Produced by Streptomyces sp. RSP9. II. Physico-chemical Properties and Structure Determination.
New Insights into Rifamycin B Biosynthesis: Isolation of Proansamycin B and 34a-Deoxy-rifamycin W as Early Macrocyclic Intermediates Indicating Two Separated Biosynthetic Pathways.
Identifying Protein Kinase Inhibitors Using an Assay Based on Inhibition of Aerial Hyphae Formation in Streptomyces.
PPAR.GAMMA. Activation and Adipocyte Differentiation Induced by AS-6, a Prenyl-phenol Antidiabetic Antibiotic.
Confirmation of the Antibacterial Mode of Action of SB-219383, a Novel Tyrosyl tRNA Synthetase Inhibitor from a Micromonospora sp.
Synthesis and In Vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived From Tylosin.
Microbial Hydroxylation of Zofimarin, a Sordarin-related Antibiotic.
Absolute Configuration of Migrastatin, a Novel 14-Membered Ring Macrolide.
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Novel .ALPHA.-Glucosidase Inhibitors, CKD-711 and CKD-711a Produced by Streptomyces sp. CK-4416. I. Taxonomy, Fermentation and Isolation.
Novel .ALPHA.-Glucosidase Inhibitors, CKD-711 and CKD-711a Produced by streptomyces sp. CK-4416. II. Biological Properties.
Novel .ALPHA.-Glucosidase Inhibitors, CKD-711 and CKD-711a Produced by Streptomyces sp. CK-4416. III. Physico-chemical Properties and Structure Elucidation.
Cyclipostins: Novel Hormone-sensitive Lipase Inhibitors from Streptomyces sp. DSM 13381. I. Taxonomic Studies of the Producer Microorganism and Fermentation Results.
Cyclipostins, Novel Hormone-sensitive Lipase Inhibitors from Streptomyces sp. DSM 13381. II. Isolation, Structure Elucidation and Biological Properties.
Helicobacter pylori May Survive Ampicillin Treatment in the Remnant Stomach.
Synthesis and Anti-Helicobacter pylori Activity of Pyloricidin Derivatives. II. The Combination of Amino Acid Residues in the Dipeptidic Moiety and its Effect on the Anti-Helicobacter pylori Activity.
A Novel Neuronal Cell Protecting Substance,Halxazone,Produced by Streptomyces halstedii.
GTRI-BB,a New Cytotoxic Isochromanquinone Produced by Micromonospora sp. SA-246.
Queenslandon, a New Antifungal Compound Produced by Chrysosporium queenslandicum: Production, Isolation and Structure Elucidation.
The Structure of V214w From an Unidentified Fungus.
A Trimer of Phenoxymethyl Penicillin Sulphone: Synthesis of a New .BETA.-Lactam Podand.
Aminoglycoside Antibiotics Bind to Protein Disulfide Isomerase and Inhibit Its Chaperone Activity.
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Argyrins, Immunosuppressive Cyclic Peptides from Myxobacteria. I. Production, Isolation, Physico-chemical and Biological Properties.
Fungal Metabolites, Asterric Acid Derivatives Inhibit Vascular Endothelial Growth Factor (VEGF)-induced Tube Formation of HUVECs.
Atroviridins A-C and Neoatroviridins A-D, Novel Peptaibol Antibiotics Produced by Trichoderma atroviride F80317. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Arylomycins A and B, New Biaryl-bridged Lipopeptide Antibiotics Produced by Streptomyces sp. Tue 6075. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Arylomycins A and B, New Biaryl-bridged Lipopeptide Antibiotics Produced by Streptomyces sp. Tue 6075. II. Structure Elucidation.
Biosynthesis of the Cyclitol Moiety of Pyralomicin la in Nonomuraea spiralis MI178-34F18.
Characterization of Mycotypha Metabolites Found to be Inhibitors of Cell Adhesion Molecules.
Asterobactin, a New Siderophore Group Antibiotic from Nocardia asteroides.
Structure Elucidation of a New Cyclic Hexadepsipeptide from Beauveria felina.
A Method to Assay Glyoxylate Cycle Inhibitors for Antifungals.
Inhibitory Activity of Dome Formation in LLC-PK1 Cells Is a Selective Index of Aminoglycoside Nephrotoxicity.
UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02 VI(2). Structure-activity Relationships of UK-2A.
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Kynapcin-13 and -28, New Benzofuran Prolyl Endopeptidase Inhibitors from Polyozellus multiplex.
A Novel Neuritogenic Compound, NGA0187.
Structure and Biosynthesis of Cetoniacytone A, a Cytotoxic Aminocarba Sugar Produced by an Endosymbiontic Actinomyces.
Phytotoxic Arylethylamides from Limnic Bacteria Using a Screening with Microalgae.
An Unexpected Inhibitory Effect of Rapamycin against Germination of Spores of Bacillus brevis Strain Nagano.
New Dioxopiperazine Metabolites from a Fusarium Species Separated from a Marine Alga.
Acremonol and Acremodiol, New Fungal Bislactones.
Synthesis of (-)-Galiellalactone.
Structure of Aspochalasin H, a New Member of the Aspochalasin Family.
A Novel Dihydroxanthenone, AGI-B4 with Inhibition of BEGF-induced Endothelial Cell Growth.
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TMC-256A1 and C1, New Inhibitors of IL-4 Signal Transduction Produced by Aspergillus niger var niger TC 1629.
Aspergillin PZ, a Novel Isoindole-alkaloid from Aspergillus awamori.
New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233. I. Taxonomy, Fermentation, Isolation and Biological Activities.
New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233. II. Physicochemical Properties and Structure Elucidation.
Identification of L-Glutamine: 2-Deoxy-scyllo-inosose Aminotransferase Required for the Biosynthesis of Butirosin in Bacillus circulans.
Argyrins, Immunosuppressive Cyclic Peptides from Myxobacteria. II. Structure Elucidation and Stereochemistry.
New Anti-MRSA and Anti-VRE Carbapenems; Synthesis and Structure-activity Relationships of 1.BETA.-Metyl-2-(thiazol-2-ylthio)carbapenems.
F-10748 A1,A2,B1,B2,C1,C2,D1 and D2, Novel Papulacandins.
Pteridic Acids A and B, Novel Plant Growth Promoters with Auxin-like Activity from Streptomyces hygroscopicus TP-A0451.
Synthesis, and Cytotoxic Activity of Nind-Alkoxy Derivatives of Antibiotic Arcyriarubin and Dechloro-rebeccamycin Aglycon.
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Nigerloxin, a Novel Inhibitor of Aldose Reductase and Lipoxygenase with Free Radical Scavenging Activity from Aspergillus niger CFR-W-105.
Biosynthetic Capacities of Actinomysetes. No.26. Endophenazines A-D, New Phenazine Antibiotics from the Arthropod Associated Endosymbiont Streptomyces anulatus. I. Taxonomy, Fermentation, Isolation and Biological Activities.
Biosynthetic Capacities of Actinomysetes. No.27. Endophenazines A-D, New Phenazine Antibiotics from the Athropod Associated Endosymbiont Streptomyces anulatus. II. Structure Elucidation.
New Derivatives of Tylosin: Chemical and Electrochemical Oxidation Products of Desmycosin.
Hexacylinol, a New Antiproliferative Metabolite of Panus rudis HKI 0254.
Agrocybolacton, a New Bioactvi Metabolite from Agrocybe sp. HKI0259.
Oxasetin, a New Antibacterial Polyketide Produced by Fungus Vaginatispora aquatica, HK1821.
Formation of Anion-selective Membrane Pores by Texenomycin A, a Basic Lipopeptaibol Antibiotic.
Epoxyquinol B, a Fungal Metabolite with a Potent Antiangiogenic Activity.
In Vitro and In Vivo Antimalarial Activities of the Monoglycoside Polyether Antibiotic, K-41 against Drug Resistant Strains of Plasmodia.
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CJ-15,208, a Novel Kappa Opioid Receptor Antagonist from a Fungus, Ctenomyces serratus ATCC15502.
GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. I. Taxonomy, Production, Isolation, Physicochemical Properties and Biological Activities.
GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. II. The Effects on Cell Cycle Progression and Gene Expression.
TPU-0037-A, B, C and D, Novel Lydicamycin Congeners with Anti-MRSA Activity from Streptomyces platensis TP-A0598.
Altersetin, a New Antibiotic from Cultures of Endophytic Alternaria spp. Taxonomy, Fermentation, Isolation, Structure Elucidation and Biological Activities.
Chalcomycin B, a New Macrolide Antibiotic from the Marine Isolate Streptomyces sp. B7064.
Strain Diversity within a Microbial Collection.
Reveromycin A Inhibits Antigen Receptor-mediated Antigen Presentation by B Lymphoma Cells via Its Effect on Intracellular Trafficking of the Antigen.
Isolation and Structure Elucidation of Two New Antibacterial Compounds Produced by Chrysosporium queenslandicum.
Detection of the Mevalonate Pathway in Streptomyces Species Using the 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene.
Studies on Bottromycins. II. Structure Elucidation of Bottromycins B2 and C2.
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Thielavins as Glucose-6-phosphatase (G6Pase) Inhibitors: Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities.
New Antibiotics Miyakamides Produced by a Fungus.
Isolation of Temperature-sensitive Saccharomyces cerevisiae with a Mutation in erg25 for C-4 Sterol Methyl Oxidase.
PF1163A, a Novel Antifungal Agent, Inhibit Ergosterol Biosynthesis at C-4 Sterol Methyl Oxidase.
S-3578, A New Broad Spectrum Parenteral Cephalosporin Exhibiting Potent Activity Against both Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa Synthesis and Structure-activity Relationships.
Synthesis of Milbemycins .ALPHA.9, .ALPHA.10, .ALPHA.11, .ALPHA.12, .ALPHA.14, .ALPHA.15, .ALPHA.20, .ALPHA.21, .ALPHA.22, .ALPHA.23, .ALPHA.26, .ALPHA.27, .DELTA.2,3,.DELTA.4,26-Milbemycins A3, A4 from Milbemycins A3, A4, and Their Acaricidal Activities.
Phenylpyropene A and B, New Inhibitors of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium griseofulvum F1959.
Identification of 6-Prenylindole as an Antifungal Metabolite of Streptomyces sp. TP-A0595 and Synthesis and Bioactivity of 6-Substituted Indoles.
Screening of Interleukin-2 Production Inhibitor with Mouse Thymoma EL4 Cells.
First Identification of Streptomyces Genes Involved in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics. Genetic and Evolutionary Analysis of L-Glutamine: 2-deoxy-scyllo-inosose Aminotransferase Genes.
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Parimycin: Isolation and Structure Elucidation of a Novel Cytotoxic 2,3-Dihydroquinizarin Analogue of .GAMMA.-Indomycinone from a Marine Streptomycete Isolate.
YM-202204, a New Antifungal Antibiotic Produced by Marine Fungus Phoma sp.
A Novel Potent Cell Cycle Inhibitor Dehydrophenylahistin. Enzymatic Synthesis and Inhibitory Activity toward Sea Urchin Embryo.
Selective Production of Fungal Beauveriolide I or III by Fermentation in Amino Acid-supplemented Media.
kasT Gene of Streptomyces kasugaensis M338-M1 Encodes a DNA-binding Protein which Binds to Intergenic Region of kasU-kasJ in the Kasugamycin Biosynthesis Gene Cluster.
Cloning of the Staurosporine Biosynthetic Gene Cluster from Streptomyces sp. TP-A0274 and Its Heterologous Expression in Streptomyces lividans.
Chloroquinocin, a Novel Chlorinated Naphthoquinone Antibiotic from Streptomyces sp., LL-A9227.
Total Synthesis of a Tetracyclic Anti-tumor, UCE6.