List of Jounal Titles
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Jpn J Pharmacol
94
Supplement 1 - Interleukin 6; From Laboratory to Clinic
- .BETA.-Arrestins: Master Regulators of Seven Membrane Spanning Receptors
- Pathophysiology of Chloride Transport: Lessons from Mouse Models and Human Disease
- Neuroinformatics: A New Path to Drug Development
- Gene Hunting in Cardiovascular Diseases
- Studies on molecular mechanisms for pain and its control
- TRANSPORTERS AND NEW DRUG DEVELOPMENT
- Structure Analysis and Molecular Interaction of Proteins for Rational Drug Design
- On the advances of gastric studies over the past 40 years
- Molecular mechanisms and therapeutic strategies for prion diseases
- Molecular and pharmacological basis for the gating regulation of voltage-dependent L-type Ca2+ channels
- Analysis of PKC and DGK functions using live imaging technique
- An independent, non-neuronal cholinergic system in lymphocytes and its roles in regulation of immune function
- Role of the CD47-SHPS-1 system in regulation of cell migration and macrophage phagocytosis
- A novel Ras family protein ERas that promotes embryonic stem cell proliferation
- An RNA-binding protein-mediated feedback regulation of MAPK signalling
- Regulation of neuronal functions in by Wnt signal
- Clinical usefulness and risk of Ikr Blocker
- Antiarrhythmic and proarrhythmic effects of IKr blockers in in vivo animal models
- Cellular Mechanism of Drug-induced QT Prolongation and Torsade de Pointes
- Electrophysiological assessment of the risk of drug-induced long QT syndrome using patch clamp techniques
- The molecular mechanism of the action of Ikr blockers and simulation of their proarrhythmic effects
- Structure and function of protein tyrosine phosphatases
- The role of LAR class protein tyrosine phosphatase in axon guidance
- A novel cell-cell communication system, which acts through tyrosine phosphatase SHP-2: Its function in the central nervous system
- MAP Kinase and its regulation through protein tyrosine phosphatases
- SHP-2 tyrosine phosphatase as a cellular target of the H. pylori oncogenic factor CagA
- VacA of Helicobacter pylori induces gastric ulcer through protein tyrosine phosphatase .ZETA. (PTP.ZETA.) signaling
- Mechanisms of psychobehavioral deficits in schizophrenic animal models: an approach from monoaminergic and glutamatergic neuronal systems
- Relevance of PACAP-deficient mice as an animal model of psychiatric disorders
- Monoamine neurotransmission and mental disorders
- Regulated expression of catecholamine transporter isoforms produced by alternative splicing
- Norepinephrine transporter and drugs for the treatment of psychiatric disorders
- Long-lived retrograde fluorescent labeling of specific neurons in the living animal
- Development of Novel Fluorescence Probes Based on Rational Design Principles
- Monitoring synaptically released glutamate by use of the voltage-sensitive dye imaging technique
- Presynaptic Ca2+ dynamics revealed by selective axonal labeling in brain slice
- Ca2+ imaging in neurons: from in vitro to in vivo
- Neural mechanisms of social cognition and emotional expression in the monkey amygdala
- Behavioral approaches for emotion in the prostaglandin E receptor mutant mice
- Emotional stress and an agerelated functional development of the rat brain
- Neural basis of emotion and feeling from a neuropsychological perspective
- Neuromaging Research on Human Emotion with Positron Emission Tomography
- Roles of Disrupted-in-Schizophrenia-1 (DISC1) in neuronal morphologies and functions
- Distinct neurite-extension induced by two lipid-related kinases
- Dendritic spine morphogenesis
- Dynamic regulation of motor protein and microtubule network in migrating neurons
- Regulation of insulin signal and its disorder
- Oxidative stress in diabetes
- Regulation of phosphorylation of tau by insulin and Ca2+ signals
- Brain aging and Insulin signal
- Expression of insulin receptor's signaling molecules: constitutive and inducible regulatory mechanisms
- Regulation mechanism of histamine H1 receptor expression and its significance
- Desensitization and internalization of Gq protein-coupled histamine H1 receptors
- The role of mast cell on allergic inflammation
- The role of eosinophils in allergic inflammation
- Analyses of induction mechanisms of allergic rhinitis by using a guinea pig model
- Clinical evaluation of newly antihistamines, physician's preference and pharmacodynamics
- Mouse Molecular Genetics in the Analysis of Obesity and Diabetes
- Nuclear receptors on stem cells
- Cholesterol and bile acid metabolisms regulated by nuclear receptors
- Molecular mechanism of crosstalk between PPARgamma and cytokines
- Nuclear factors in mast cells; their roles in inflammation
- Distribution of adrenomedullin-containing perivascular nerves and its alteration in hypertension
- ROS in experimental hypertension
- Hemoglobin-nitric oxide complex (HbNO) formation from nitrite
- Mechanisms underlying endothelial dysfunction in the insulin-resistat state
- Two faces of eNOS/NO system in hypercholesterolemia and atherosclerosis
- Mechanism underlying the regulation of serotonin transporter function
- Serotonin transporter gene polymorphisms and psychiatric disorders
- Clinical efficacy of SSRI for anxiety and depressive disorders and its mechanism of action
- Serotonin Transporter and Pediatric Disease
- Regulatuion of Cdk inhibitor p27Kip1
- Disturbed Cell Cycle Regulation of Neural Progenitor Cells and Neocortical Dysgenesis
- Roles of cyclin-dependent kinases for neuronal cell death
- Aberrant cell cycle progression in neuronal cell death
- Introduction and expression of acetylcholine in living organisms
- Expression of nicotinic acetylcholine receptors and their roles in regulation of immune function
- Evolution of cholinergic system viewed from a basal metazoan Hydra
- Role of nicotinic receptors in neuron survival
- Functional analyses of neuronal nicotinic receptors in midbrain and skeletal muscles using knockout mice
- Regulation of regional cerebral blood flow through nicotinic acetylcholine receptor-mediated pathways
- Recent progress in medical treatment of osteoporosis
- Animal model of antiepileptics induced osteoporosis
- Antiapoptotic function of antiosteoporosis
- Regulation of osteoblast differentiation and bone formation by runt-related transcription factor 2 (Runx2)
- Neural regulation of bone metabolism
- Endoplasmic reticulum (ER) stress as the signaling mechanism of neurodegeneration
- Astrocyte-specific unfolded protein response and regulation of apoptosis after ER stress
- Protective effects of HRD1 and 4-phenylbutyric acid against neuronal cell death
- NO-induced apoptosis and ER stress in microglia
- Stress proteins and regulation of microglial amyloid-.BETA. phagocytosis
- New insights into the cellular mechanisms to control the mechanical activity of urinary bladder smooth muscle and possible approaches towards the development of novel types of therapeutic agents for urologic diseases
- Acidic pH-induced contraction in rat aorta
- New approach for development of antiarrhythmic drugs
- Development of Ca2+-handling modulator and Ca2+ sensitizer in heart diseases
- Development of cardiovascular drugs and their clinical application
- Molecular Mechanism of Drug Abuse and Development of Drugs
- Morphine tolerance and addition-involvement of antiopioid neuronal networks in its plasticity
- Involvement of tissue plasminogen activator-plasmin system in morphine-induced rewarding effects
- Involvement of glutamate transporters in drug dependence
- Role of glial cells in the development of drug dependence
- Methamphetamine psychosis-Molecular mechanisms related to the functions of Arc, Amida and Arcadlin
- Infliximab (Remicade)-A novel therapy for inflammatory diseases by targeting TNF.ALPHA.
- Effects of Eternercept (Enbrel) on RA Animal Models and Patients
- Research for anti-IL-6 receptor antibody, a novel anti-rheumatic agent
- Pharmacological actions of tacrolimus (FK506) as an anti-rheumatic drug
- Pharmacological and clinical effect of T-614 (Iguratimod), an anti-rheumatic drug
- The mechanism of inhibition of bone destruction by leflunomide
- Pharmacology of olfactory receptors: molecular basis for odorant discrimination
- Physiology and pharmacology of the visceral afferent information
- Molecular mechanisms of thermosensation: TRP channel thermoceptors
- The role of ATP receptors in the pain sensation
- Role of endothelin in progression of cardiac remodeling and failing heart
- STAT3 as a therapeutic target for heart failure
- MAP kinase cascades and cardiac remodeling
- Dysfunction of cardiac contractile regulatory mechanisms
- New Era to Find Novel Causes and Treatments of Chronic Heart Failure from Genomic and Clinical Database
- Signal transduction of CaM-kinase cascade and its specific inhibitor
- The regulatory mechanism of Ca2+/calmodulin-dependent protein kinase I
- Variable domain of CaM kinase II
- Calcineurin and mental disorders
- Involvement of Ca2+/calmodulin (CaM) in neuronal cell death
- Channel/Transporter and Disease-Overview-
- Potassium ion channels and heart diseases
- P type Ca channel and Spinocerebellar ataxia
- A new mechanism of myocyte degeneration involving Ca2+-permeable non-selective cation channel
- Neutral amino acid transporter LATs as targets for anti-cancer therapy
- Role of the glutamatergic neurotransmission in the basolateral amygdaloid nucleus in pain-related aversion
- Opioids and emotion-Clinical implications for neuro-psychological disorders-
- Regulation of emotional behavior by nuclear receptors
- Molecular dissection of depression using animal models
- Polymorphism of the peripheral-type benzodiazepine receptor gene associated with the trait of anxiety
- Molecular and Neural Bases of Cytoarchitectural Organization of the Developing Neocortex
- Intrinsic factor to fix GABAergic neuron number in the neocortex
- Induction of neural differentiation and its application for the regeneration
- Signaling at the growth cone and regenerative medicine
- Molecular mechanism of the enhancement of neuronal functions by V-1, a novel ankyrin repeat protein and its potential application to drug development
- Abnormal behavior associate with CB1 cannabinoid receptor and develop to therapeutic application
- Physiological roles of endogenous cannabinoid receptor ligands
- Endocannabinoid-mediated retrograde modulation of synaptic transmission in the CNS
- Genetic association between schizophrenia and the central cannabinoid receptor gene
- Involvement of endocannabinoid in drug dependence and brain reward system
- Overview: Multiplicity, Tissue Specificity and Genetic Polymorphism of Drug Transporters
- ABC proteins as molecular targets for drug discovery
- Involvement of membrane transporters in drug absorption
- Drug transporter studies in drug discovery and development
- Pharmacological role of HB-EGF shedding by angiotensin II in cardiomyocyte
- Chymase-derived angiotensin II and arrhythmias after myocardial infarction
- Combination therapy of angiotensin receptor blocker and aldosterone receptor blocker on cardiovascular remodeling
- Mineralocorticoid receptor antagonist spironolactone improves left ventricular remodeling
- Role of aldosterone in the progression of renal injury
- Novel proteins protecting from cell death induced by Alzheimer's disease-related proteins
- Memantine: overview and the effect on the animal models of Alzheimer's disease
- Evaluation of therapeutic drugs for Alzheimer's type dementia with animal PET
- Scope and Limitation of Acetylcholinesterase Inhibitors
- Galantamine and risperidone in dementias
- The mechanisms of protein nitration
- Possibility of Denitrating Activity
- Nitration of steroid hormone receptors and their functional changes
- Tyrosine nitration and neurodegenerative disorders
- Oxidation and nitration of low-density lipoproteins
- Histone decetylase Sir2.ALPHA. affects proliferation and differentiation of neural stem cells
- Expression and function of Forkhead transcription factors in neurons
- Transcriptional regulation of BDNF gene and its physiological role in neuron
- Gene expression in response to brief magnetism in cultured rat hippocampal neurons
- Transcriptional regulation of NPY gene and its effect on feeding
- KEGG for pharmaceutical sciences
- Pharmacogenomics and pharmacoinformatics
- Novel drug discovery based on genome informatics
- Personalized medicine and bioinformatics
- Roles of Nox1 in innate immune responses and carcinogenesis in the stomach
- ROS generation via PKC-induced p47 & p67 phox translocation
- A role of vascular NAD(P)H oxidase in diabetic vascular complications
- Essential roles of transactivation of EGF receptor and mitochondria in induction of NOX1, a catalytic subunit of NADPH oxidase
- NADPH oxidases in vascular endothelial and smooth muscle cells
- Sleep-wake regulation by histamine
- Histamine synthesis in mast cells upon sensitization with IgE
- Role of Histamine in Angiogenesis in Granulation Tissue
- Targeted disruption of H3 receptors results in changes in brain histamine tone leading to obese phenotype
- Role of semaphorins and their receptors, neuropilins and plexins, in axon guidance
- Functional roles of Cdk5/p35 in brain development
- Dual phosphorylation signaling for axon terminal differentiation of zebrafish olfactory sensory neurons
- Control of axon formation and outgrowth by Rho signaling
- Introduction
- Characterization of KIDScPLA2 and its role in the CNS
- Epileptic seizure and prostaglandins
- Effects of prostaglandin receptor stimuli on neurogenesis in the dentate gyrus of the adult rat
- The prostaglandin EP3 receptor-mediated central neural pathway for the regulation of the sympathetic system
- Prostanoid receptor-dependent mechanism regulating stress-related behaviors
- Induction of microsomal PGE synthase-1 in the brain and its essential role in fever
- Cellular regulation of aquaporin-2 in hereditary nephrogenic diabetes insipidus
- Aquaporins: Structure-Functional Relationships
- Aquaporins and caveolae
- Expression of aquaporin in brain microvessels: effects of astrocyte derived factor and hypoxia
- The defect of translocation of aquaporin-5 in rat parotid glands leads to xerostomia
- The function and role of aquaporin superfamily
- SEA0400, a selective inhibitor of the Na+-Ca2+ exchanger
- Functional role of high voltage-gated calcium channels (HVCCs) in drug dependence
- Desensitization of NMDA receptor channels
- Roll of Calcium/calmodulin dependent protein kinases in ischemic neuronal death
- Calcium receptor agonist (calcimimetics): therapeutic potential in hyperparathyroidism
- DJ-1, a protein responsible for Parkinson's diseases (PARK7), plays a role in the anti-oxidative stresses
- Amyloid .BETA.-peptide-induced neurotoxicity and its protective substances in cultured hippocampal neurons
- Biochemical and immunocytochemical study on FTDP-17-From patients to mice-
- Neuronal death and regeneration in the hippocampal dentate gyrus
- Upregulated genes during fish optic nerve regeneration
- Intracellular localization and activity regulation of 5-lipoxygenase
- Cysteinyl-leukotriene (CysLT) production and pathobiology
- Pathophysiological roles of leukotriene receptors
- The role and mechanism of 12/15-lipoxygenase in the development of atherogenesis
- Control of the arachidonate cascade and its role during the changes in the life cycle of adipocytes
- Clinical perspective of wound healing-Control the process by growth factor-
- Cell Proliferation: Drug Development and Control of Fibroblast Proliferation
- Regulatory mechanisms of fibroblast contraction in wound healing processes
- Control of Apoptotic System in Wound Healing
- Recent Progress in Technology for Skin-regeneration Therapy-Cell to Extracellular Matrix Interactions, Transgenesis, and Hair Follicle Regeneration in Relation to Artificial Skin-
- Proteinase-mediated Signaling: PARs and More
- Role of tryptase/PAR-2 in vascular endothelial barrier function
- Signal transduction via protease-activated receptors in the respiratory system
- Mast cell tryptase and PAR-2-mediated proliferation of colon cancer cell
- Regulatory mechanism for the expression of protease-activated receptors: A role of small G proteins
- Protease-activated receptor-2 (PAR-2) as a potential therapeutic target
- Physiological and pathophysiological significances of Ca2+-permeable AMPA receptors in glial cells
- Molecular mechanism underlying the regulation of AMPA receptor activity
- Locus-specific rescue of GluR.EPSILON.1 recovers morphine tolerance and dependence
- Conditional ablation of glutamate receptor .DELTA.2 induces synaptic rearrangements in mature cerebellum
- Structiue and function of mGluR
- Two novel transcripts for human endothelin B receptor produced by RNA editing/alternative splicing from a single gene
- Regulation of purinergic signaling by receptor oligomerization
- Multiple processing of Ig-Hepta, a G protein-coupled receptor with immunoglobulin (Ig)-like repeats
- Heterogeneity generated from differential regulation of receptor subtypes
- Nonclinical assessment of the potential for QT interval prolongation by pharmaceuticals
- The clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs
- An overview of "QT PRODACT" (QT Interval Prolongation: Project for Database Construction)
- Integrated Risk Assessment: Consideration to Safety Margin
- The significance of thorough QT/QTc study in clinical drug development
- Genetic background for secondary long QT syndrome: an old but newly developed concept to prevent the drug-induced torsade de pointes
- Structure-Function of a cloned Stretch-Activated BK Channel (SAKCaC) from hearts and hunting its blockers
- PECAM-1/CD31 acts as a mechanotransducer in vascular endothelial cells
- Shear-stress sensing via P2 purinoceptors in vascular endothelial cells
- Role of lysophosphatidic acid as a mechanosensitizer
- Mechanical stretch inhibits adipocyte differentiation of 3T3-L1 cells
- Regulation of the function of the endoplasmic reticulum by transcriptional induction systems
- ER-associate degradation (ERAD) as a quality control mechanism of terminally misfolded proteins
- Dynamics of proteins in the endoplasmic reticulum
- The KDEL receptor contributes to the endoplasmic reticulum quality control
- The role of molecular chaperones in cystic fibrosis
- Dimerization and quality control of receptor tyrosine kinase by chaperones
- Importance of research on alternatives to animal experiments and its current issues
- Animal Experiment: Laboratory animal welfare is different from anti-animal experiment activity
- Deployment in the animal experiment by the embryonic stem cells
- Feasibility study on engineered biohybrid cell culture systems as a new cytotoxicity test
- Alternatives to animal testing for evaluating local irritations
- Alternative animal experiments for drug investigations
- Primary sensory neurons express the high affinity IgG Fc.GAMMA.RI receptor and responds to IgG-antigen complex
- Cystine oxidation activates Ca2+-permeable cation channel TRPC5
- Study on the role of TRPM2 in primary cultured cerebral cortical neurons from rat fetal brain
- Requirement of p38 MAPK activation for the induction of Grp78 by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells
- The expression of BMP7 and receptors in the salivary glands of mice and the cytoprotective effects from diabetic stresses
- The defect of translocation of AQP5 in parotid glands of streptozotocin-induced diabetic rats
- COX-II inhibitor blocks progesterone and PGE2 productions induced by VEGF in ovarian luteal cells
- Retarded onset of hyperglycemia in calmodulin transgenic mice by exendin-4
- Regulation of FSH.BETA. gene expression in L.BETA.T2 cells
- Effects of St. John's wort on [3H]5-HT uptake and [3H]paroxetine binding in mouse brain
- Serotonin (5-HT) hyperpolarized orexin neurons via a 5-HT 1A receptor
- Parallel fiber-induced inositol 1,4,5-trisphosphate production in cerebellar Purkinje cells is mediated cooperatively by group I metabotropic glutamate receptor and the AMPA receptor
- Involvement of NMDA receptor in the locus coeruleus in the antinociception through supraspinalP2X receptors
- Mechanism of the contraction induced by bradykinin in the guinea-pig taenia coli
- Effects of ACE inhibitor and AT1 antagonist on duodenal HCO3-secretion in rats: Involvement of endogenous PG, NO and bradykinin
- Comparison of cisplatin, cyclophosphamide, 5-fluorouracil and vincristine in the induction of pica in rats
- Expression of acetylcholine in archaea
- Substance P functions as a modulator of corneal epithelial migration through activation of calmodulin-dependent protein kinase II
- The involvement of the arachidonic acid cascade and inflammatory cytokines in impairment of working memory induced by a .BETA.-amyloid precursor protein (CT105)
- Targeted introduction of V642I mutation in amyloid protein precursor gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice
- Microglial amyloid-.BETA. clearance and regulatory factors
- Novel PET probe for in vivo imaging amyloid plaques in the brain
- Effects of Urocortin II on rat cardiomyoctes
- Skeletal myoblasts (SkM) transplantation to treat dilated cardiomyopathy (DCM) hamsters
- Properties of endothelin-1-induced negative inotropic effect in adult mouse ventricular myocytes
- Spatial differences in the effect of ion channel blockers on atrial electrophysiology
- Macrophage Migration Inhibitory Factor Enhances Inflammatory Second Attack of the Heart in Pancreatitis Mice
- Involvement of concentrative and equilibrative nucleoside transporters in hydrogen peroxide-induced thymidine incorporation and delayed cell death in cultured astrocytes
- Detection of nitric oxide (NO)-generating activity in the inflammed brain region of cathepsin D-deficient (CD-/-) mice
- Possible involvement of protein kinase C in the dysfunction of spinal NO/cGMP pathway in vincristine-induced hyperalgesia in mice
- Effect of L-NAME on central .ALPHA.2-adrenoceptor-mediated hypertensive response in freely moving rats
- Upregulation of angiotensin II type-2 receptor in mouse aorta by pressure-overload
- Roles of angiotensin II type-1 receptors on the development of nitrate tolerance in rabbit mesenteric resistance artery
- Subtype Selective binding affinities of Human Adrenergic Receptors to Carvedilol
- Effect of Rho kinase inhibitor on hypertension and catecholamine synthetic pathway of spontaneously hypertensive rats
- Pharmacological characterization of .ALPHA.1a- and .ALPHA.1b-adrenoceptors co-expressed in HEK 293 cells
- The role of PAF in transduction of pain in spinal cord-induction of hyperalgesia and allodynia
- Glutamic acid receptor contributes to primary afferent depolarization in rat spinal cord
- Microfilament-ssociated protein increases the membrane expression of TRPV4
- Presynaptic localization of neprilysin contributes to efficient clearance of A.BETA. in mouse brain
- Spontaneous "gliotransmission" by ATP causes switching-over of intracellular signaling-cascades in cultured hippocampal astrocytes
- Signaling mechanism underlying the positive modulation of Na+-Ca2+ exchanger via angiotensin II receptor stimulation in mouse ventricular myocytes
- Calcium channel blocking action of sardine peptides on the rat thoracic aorta
- Properties of the voltage-dependent Ca2+ current in porcine sino-atrial node cells
- Probing the IIIS5-S6 linker region of L-type Ca2+ channel .ALPHA.1c subunit (Cav1.2) by SCAM analysis
- Mechanosensitive potentiation of receptor-activated TRPC6 channels
- Activation of protease-activated receptor 1(PAR1) stimulates nociception through cyclooxygenase-dependent pathway
- Lack of sleep rebound after sleep deprivation in adenosine A2A receptor-deficient mice
- Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats
- Progressive degeneration of dopamine neurons detected by PET after repeated administration of MPTP in crab-eating monkeys
- Akt and Ca2+ signaling in endothelial cells
- Nattokinase enhances thrombolysis after endothelial injury in mouse femoral artery via t-PA concerned mechanism
- The nucleotide-binding domains of SUR2A and 2B play different roles in the response of KATP channels to nicorandil
- Validation of [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels
- A rapid and sensitive method to demonstrate QT prolongation by HERG inhibitors in anesthetized Guinea pigs
- PKC.DELTA. plays an important role in VEGF/KDR signaling
- H2O2 activates Na+/Ca2+ exchange through MAPK kinase pathways in guinea-pig ventricular cells
- The aligned cardiomyocytes lead to the localization of Cx43 at the intercalated disk through N-cadherin/Rho pathway
- Effects of uroguanylin on circulation in Dhal-Iwai salt-sensitive rats
- Role of p38 mitogen-activated protein kinase in thrombus formation
- INVOLVEMENT OF BRAIN PERICYTES IN CYCLOSPORIN A-INDUCED DYSFUNCTION OF THE BLOOD-BRAIN BARRIER
- Effects of cocultured pericytes on the blood-brain barrier (BBB) functions in vitro BBB models
- Cathepsin E deficiency and brain functions
- Effect of tissue plasminogen activator inhibitor on dopamine release in vivo
- Effect of human histidine rich glycoprotein on neutrophil function
- Implication of Ca2+ entry through oxidative stress sensitive TRPM2 channel on IL-8 production by H2O2 in U937 cells
- Potent inhibition of B cell receptor signaling by a novel Ca2+ channel blocker
- Preventive effect of vitamin E on blue light induced lipid peroxidation in porcine retinal homogenate
- Thrombin-induced glucose transport via src-p38MAPK pathway in vascular smooth muscle cells
- PDGF Stimulates Big Mitogen-Activated Protein Kinase 1 (BMK1) in Vascular Smooth Muscle Cells
- Differential expressions of .ALPHA.2D-adrenoceptor and eNOS in aortae from early and later stages of diabetes in Goto-Kakizaki rats
- EDHF in the vasodilatation of the peripheral resistant vessels of the rat
- Cadherin activity is required for the remodeling of synaptic membranes
- Regional differences in milnacipran-induced synaptic plasticity between prefrontal cortex and hippocampus
- Regulation of synaptic transmission in hippocampus by ATP from astrocyte
- Encoding of synaptic history via redistribution in hippocampus
- The effect of scopolamine perfusion to the medial frontal cortex (mFC) and posterior cingulate/retrosplenial cortex (PC/RSC) of the MK-801 treated rat
- Switchable RNAi in mammalian cells
- Drug target identification and validation by in silico analysis
- Molecular Evolutionary Analysis of Proteins in Neurotransmitter System
- Cloning of chaperonin cct .GAMMA. gene essential for zebrafish retinotectal development by whole-genome subtraction
- A genome-wide transcriptome analysis of spinal ligament cells from patients with ossification of the posterior longitudinal ligaments, after exposure to mechanical stress
- Contribution of Rho/Rho-kinase pathway to cell migration in arteriosclerosis
- Chronological changes of diameter, functional properties, and morphology of vasospastic artery in canine two-hemorrhage model
- Aldose reductase exacerbates ischemia-reperfusion injury in isolated mouse hearts
- Cardiac function of a transgenic mouse model of .DELTA.Glu160 troponin T mutation-linked familial hypertrophic cardiomyopathy
- Roles of brain phospholipase C and diacylglycerol lipase in vasopressin-induced activation of the central sympatho-adrenomedullary outflow in rats
- Insulin receptor signaling: up-regulation by nicotinic receptor
- The emetic, hypothermic, and anti-emetic actions of centrally administered vanilloids in Suncus murinus
- Involvement of Rho kinase in nerve stimulation-induced catecholamine release and vasoconstriction potentiated by lysophosphatidylcholine
- Effect of procaine on excitation-contraction coupling in skeletal muscle
- Activation of pro-matrix metalloproteinase-2 by chymase on human fibrosarcoma cell (HT-1080)
- Caspase-dependent apoptosis induced by lipophilic statins in cultured human hepatocytes
- Expression and role of PPAR.GAMMA. on human oral squamous cell carcinoma
- PIP3 and Ca2+/calmodulin competitively bind to the RGS domain of RGS4 and reciprocally regulate its action
- Phosphorylation of PKC activation loop plays an important role in receptor-mediated translocation of PKC
- The CGRP receptor subtypes associated with receptor activity-modifying proteins (RAMPs)
- Thromboxane A2 receptor (TP) isoforms are differently regulated by proteasome
- Subarachnoid hemorrhage induced hypercontractile response to thrombin in the rabbit basilar artery
- Sp1 regulates aquaporin-5 gene expression in alveolar epithelial cell
- Dysregulated Expression of Toll-like Receptors (TLRs) in Human Cystic Fibrosis Epithelial Cells
- Pharmacological studies on the respiratory tract (Rept. 257): Acetylcholine-induced Thr38-phosphorylation and membrane translocation of CPI-17 in bronchial smooth muscle of rats
- Role of chemical mediators on the development of chronic allergic conjunctivitis in rats
- In vitro development of intestinal tissue demonstrating rhythmic motility from embryonic mouse intestinal cells
- Immunohistochemical studies on calcium store in smooth muscle cells of rat colon
- Effect of mechanical stretch on translocation of glucose transporter 4 (GLUT4) and glucose uptake in murine skeletal muscles
- The role for tropomyosin in vascular smooth muscle cells
- Influence of aging on muscarinic and .ALPHA.-adrenergic responsiveness in the rat urinary bladder
- Selective stabilization of type 1 ryanodine receptor channel activity is mediated by intra-molecular domain-domain interactions
- Differential mechanisms for carbachol-induced Ca2+ sensitization of contractile elements in rat proximal and distal colon
- Both M2 and M3 receptor subtypes are indispensable for activation of the muscarinic receptor-operated cation channels in mouse intestinal smooth muscle cells
- Heterologous down-regulation and phosphorylation of histamine H1 receptor
- Protective effect of donepezil in a primary culture of rat cortical neurons exposed to oxygen-glucose deprivation
- INHIBITION BY ATP.GAMMA.S OF THREE TYPES OF EVOKED SYNAPTIC CURRENT VIA A1 RECEPTORS IN RAT MNTB NEURONS
- Characteristics of transgenic rats harboring a mutation underlying human autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)
- A simple screening method of bioactive substances for protecting nerves from active oxygen related injury
- Long-term exposure of cerebrocortical neurons to diazepam (DZP) induces up-regulation of L-type high voltage-gated calcium channels (HVCCs)
- Effects of DIDS and chlorpromazine on NO3- transport in erythrocytes: Inertness of DIDS in whole blood
- Pharmacological bases of Lipo-PGE1 for amelioration of peripheral circulatory disorders
- Effects of chlorinated oxidants on the arachidonic acid metabolism in rabbit platelets
- Molecular mechanism of nitric oxide release by herbal medicine, ginsenoside Re
- Nicorandil protects the anti-platelet aggregating activity of endothelial nitric oxide via the inhibition of superoxide production induced by hypoxia-reoxygenation
- Antivasospastic effect and synergistic induction of HO-1 in cerebral vasospasm following SAH
- CCK-2 receptor deficiency abolishes gastric mucosal hyperplasia induced in H2 receptor-deficient mice
- Molecular cloning and electrophysiological characterization of rat ileal CLCA isoform, a new member of the Ca2+-activated Cl- channel family
- .BETA.2-adrenoceptor gene delivery affords the kidney protection against endotoxin-induced acute renal failure
- Mechanism of stability and degradation of the chronic myelogenous leukemia oncoprotein, BCR-ABL
- Caspase-mediated signal cascade in osteoblastic differentiation
- Effect of bFGF on restoration of biomechanical properties of periodontium in replanted teeth
- Characterization of prolactin (PRL) in patients with anti-PRL autoantibodies
- Effect of disodium cromoglycate (DSCG) on late asthmatic response in guinea pigs
- The contribution of mast cells to the late-phase of asthma
- Outcomes from QT Prolongation Risk Assessment Studies
- Roles of caffeine-sensitive Ca2+ storage in contraction rate of cultured ventricular muscle cell clusters of mice
- Rapid atrial pacing upregulates synthesis of asymmetrical dimethylarginine and expression of protein arginine N-methyltransferases in canine AF model
- Molecular profile of methanesulfonanilide class III blockers
- A novel volume-regulated anion channel inhibitor, YM-255693, prevents ischemia-induced arrhythmia in rats
- Hydrogen sulfide induces calcium waves in astrocytes
- Orexin neurons receive depolarizing input from cholinergic neurons
- Protons activate the .DELTA.-subunit of the epithelial Na+ channel in humans
- Effects of GLP-1 on ion channels in cultured glia cells from the rat's cortex
- Role of Na+/Ca2+ exchanger in the regulation of vascular tone: lessons from genetically altered mice
- Molecular basis and model of ventricular arrhythmia by endothelin
- Effects of phospholipids on the oligomeric structure of phospholamban (PLN), a regulator of Ca2+-ATPase of cardiac sarcoplasmic reticulum (SR)
- Endothelin-B Receptor Signaling System Is Up-regulated in Insulin-Resistant Diabetic Rat Hearts: Potential Role in the Development of Cardiac Remodeling
- Vascular responsiveness in pithed rats with insulin resistance
- Morphine activated microglia mediated by chemotaxis and gene regulation
- Possible role of NCAM in the development of tolerance to morphine analgesia
- Combined intrathecal administration of morphine and substance P (1-7) enhances antinociceptive effect in mice
- Antagonistic property of D-Pro2-Tyr-W-MIF-1 for .MU.2-opioid receptor
- Studies on drug dependence (Rept. 388): Inhibition of the morphine-induced rewarding effect by direct activation of spinal protein kinase C in mice
- Identification of Dbl family proteins involved in endothelial mechanosensitivity
- Molecular Mechanism and Role of Endothelial MCP-1 Induction by VEGF
- Adenovirus vector induces inflammatory responses of vascular endothelium and dexamethasone optimizes its gene transduction
- Molecular cloning and analysis of a receptor for lysophosphatidylcholine in rat endothelial cells
- Transport mechanisms of a renal apical drug transporter, organic anion transporter 4
- Effects of NSAIDs on overactive bladder in rats: A comparison study of aspirin, indomethacin, and ketoprofen
- Ameliorating effects of dextromethorphan (DM) and cloperastine (CP) on overactive bladder (OAB) caused by cerebral infarction (CI) in conscious rats
- Possible involvement of nuclear factor-kappa B inhibition in the renal protective effect of oral adsorbent AST-120 in a rat model of chronic renal failure
- Preventive effect of L-carnosine on ischemic acute renal failure in rats
- Exaggerated response to environmental stimuli in the rat with traumatic events during juvenile
- Intrathecally administrated N-ethylmaleimide produces nociceptive behavior through the inhibition of endogenous dynorphin degradation in mice
- The effect of NPB on feeding behavior in mice
- Short- but not long-term treatment with edaravone, free radical scavenger, improved slowly progressive learning impairment and brain injury following neonatal hypoxic-ischemia
- Effects of the local administration of metformin on renal sympathetic nerve activity
- Cyclic AMP reverses apoptosis in cultured renal tubular cells induced by iodinated radiographic contrast media
- Involvement of ERK1/2 activation in oxidative injury induced by zinc in LLC-PK1 cells
- The activation of voltage-gated K+ channels by rosin acid
- Cyclooxygenase-2 expression in Schwann cells and macrophages in the sciatic nerve after single spinal nerve injury in rats
- Motor improvement by acute repetitive transcranial magnetic stimulation in unilateral substantia nigra lesioned-rats
- Induction of membrane-associated prostaglandin E2 synthase-1 expressed in rat brain after transient middle cerebral artery occlusion
- HGF protects the brain from ischemic injury
- The bisphosphonate drug etidronate suppresses allodynia via ATP-sensitive K+ channels in adjuvant-arthritic rats
- Genetic Mapping of Neuronal Afferents to Orexin-producing Neurons in Mice
- Depolarization-induced D2 receptor-mediated inhibition of synaptic transmission onto midbrain dopaminergic neurons
- Effect of various inducers on outgrowth of neuronal differentiation in PC12 cells
- Glutamate-induced translocation of the actin binding protein, drebrin A, from dendritic spines to the parent dendrite: Analysis using time lapse recording
- Plasma levodopa level treated with levodopa in combination with carbidopa or benserazide in Parkinson's disease
- FRET-based fluorescent probe for monitoring inositol 1,4,5-trisphosphate
- Visualization of cellular and subcellular [Ca2+] with an improved GFP-based Ca2+ probe, G-CaMP2
- The expression and distribution of peripheral type benzodiazepine receptors in the rat salivary glands
- Multicolored visualization of protein-protein interaction in living cells
- Studies on drug depencence (Rept. 389): Functional changes in dopamine D3 receptors by prenatal and neonatal exposure to bisphenol-A in mice.
- Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall
- Preparation of Diabetic Retinopathy Models with Stroke-prone Spontaneously Hypertensive Rats
- Evaluation of a guinea pig allergic conjunctivitides model using MicroAct
- Lipid Hydroperoxide induced mRNA of MMPs and TIMPs in Rabbit Retina
- Involvement of the spinal muscarinic receptors in morphine-induced anti-nociception
- Plastic change of N-type Ca channel expression after acute inflammation is responsible for hypersensitization leading to chronic pain
- Involvement of dermal ceramide elevation in antipruritic effect of histamine H1 and H2 receptor antagonists on mouse dry skin model
- Thermoregulation in TRPV1 null mutant mice
- Osmoregulation of taurine transporter mediated by TonE/TonEBP pathway as a cytoprotective response
- Roles of caffeine-sensitive Ca2+ storage in high frequency contractility of cultured ventricular muscle cell clusters of mice
- Signal transduction pathways associated with P2X7 receptor-induced cell death
- YO-2-induced apoptotic cell death is accompanied by mitochondrial dysfunction
- (R)-methanandamide as an opener of large conductance Ca2+ activated K+ channel
- Structure-activity relationship study on YO compounds as a novel class of inducer of apoptosis
- Glycogen synthase kinase-3.BETA. is tyrosine-phosphorylated by mitogen-activated protein kinase kinase 1 in human skin fibroblasts
- In silico screening of agonists and antagonists using a 3D model of P2Y1 receptor
- Anti-allergic drug oxatomide reduces the phosphorylated-Akt/PKB survival signal and induces activation of caspase-3 and -9 in Molt 4 cells
- Specific translocation and activation of DGK.ALPHA. by d-.ALPHA.tocopherol
- The effect of differentiation-inducing factor-1 on oral cancer cell lines NA and SAS
- Presence and role of drug-metabolizing enzymes in cultured rat brain microvascular endothelial cells
- Characterization of FLC4 human hepatocarcinoma cells as a model cell line for system L amino acid transporter LAT3
- Inhibitory effect of oligomycin A on the palytoxin-induced current in Xenopus oocytes
- The role of CD98 in cell adhesion and cancer
- The mechanisms of ATP release induced by adenosine in Madin Darby canine kidney cells
- Mechanism underlying anti-tumor activities by Seikareishiho: Induction of apoptosis and inhibition of telomerase in human cancer cell lines
- Binding study of NPY-Y1 receptor using IAsys
- Elemental analysis of rat basophilic leuckemia cells (2H3) by in-air micro-PIXE
- Homophilic cell-cell contact up-regulated transcription of p27Kip1 gene in endothelial cells
- Rapid induction of autotaxin by inflammatory cytokines in NIH3T3 cells
- Protective effect of D-.BETA.hydroxybutyric acid(HBA) on cell death induced by nutrient deprivation in corneal endothelial cells
- Inhibition of growth and induction of apoptosis in human cancer cell lines by Propolis
- Effect of Endodontic Agents on Cytotoxicity Induction by Sodium Fluoride
- Effects of herbal supplements on cytochrome P450-mediated metabolic activities
- The inhibitory effects of amoxapine on cytochrome P450 enzyme activities in human liver microsomes
- Participation of cotransporter in hypertonicity-induced rise in intracellular calcium concentration
- The role of glutamate in differentiation of Dictyostelium discoideum
- Nicotine receptor-mediated protective effect on tunicamycin-induced apoptosis of PC12 cells
- Induction of Apoptosis by Inhibition of Transcription Factor NF-.KAPPA.B in Human Breast Cancer MCF-7 Cells
- Caspase-independent hepatocyte apoptosis through the mitochondrial pathway induced by endogeneous oxidative stress
- Sphingosine-1-phosphate analogs induced cell death in PC12 cells
- Tumor-specific Cytotoxicity and Apoptosis-inducing Activity of .ALPHA.,.BETA.-unsaturated Ketones, Hydroxyketones and .BETA.-Diketones
- Temporal relationships among initiator caspase, effector caspase and mitochondrial depolarization
- TNF.ALPHA.-induced ROS activates the ERK/cPLA2 pathway in murine L929 fibrosarcoma cells
- Subtype-specific differences in subcellular localization of alpha1-adrenergic receptors
- Light-controlled delivery of functional protein into living cells
- Adrenergic regulations of EGF- or HGF-stimulated MAP kinase activity in primary cultures of rat hepatocytes
- Effect of hypergravity on the cell cycle progression in the vascular endothelial cells
- Cytoskeletal regulation is involved in vascular permeability mediated by endothelial cell contraction
- Carbazochrome reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine aortic endothelial cells
- Coactivation of protein kinase A and protein kinase C prevents H2O2-induced necrosis through ERK and p38 MAP kinase activation in PC12 cells
- Induction of GRP78/Bip and GRP94 expressions by peroxynitrite in human neuroblastoma SH-SY5Y cells
- Cytotoxic action of thimerosal on rat cerebellar granule cells
- Regulation of estrogen receptor function by heat shock protein 90 in HT22 cells
- Participation of reactive oxygen species and MAPK in satratoxin H-induced apoptosis in PC12 cells
- Purification of a dorsal lectin from the redfin velvetfish, Hypodytes rubripinnis
- Roles of p38 mitogen-activated protein kinase in superoxide production and chemotaxis in FMLP stimulated rat neutrophils
- The changes in the proliferation and function of mast cells due to the mutation of the c-kit receptor
- Effect of glucose removal and supplementation on the expression of asparagine synthetase in the activated mouse macrophage-like cell line
- Construction and characterization of highly constitutive active H3 receptor
- Cytoplasmic p21 inhibits stress-activated MAP kinase pathway
- Degradation of Pael-R by human HRD1 involved in ERAD
- Roles of cytoskeletal protein 4.1G in intracellular localization and signal transductions of PTH/PTHrP receptor
- Involvement of inhibition of store-operated Ca2+ entry in antiproliferative effect of amlodipine, a Ca2+ channel blocker, on human epidermoid carcinoma A431 cells
- Constitutive activity of glycogen synthase kinase-3 sustains insulin receptor's signaling molecules
- Measurement of intracellular IP3 concentration in living cells using the novel ratiometric IP3 biosensor
- .ALPHA.-Mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells
- Trafficking of Growth Hormone-Releasing Hormone Receptor (GHRHR) is affected by a mutation that disrupts its interaction with a PDZ domain-containing protein
- Study of Protein-Protein Interactions of LAT1 in Cell Membrane of Cancer Cell Lines
- Protease-activated receptor (PAR)-2-related peptides induce PAR-2-independent tear secretion
- The inhibition of interaction between HSV envelope protein, gD and cofactors at the step of viral entry by heteropolyoxotungstate, (PM-19)
- Photoaffinity labeling of HMG-CoA reductase with azido-functionalized cerivastatin derivatives
- Negative regulation of steady-state level of cell surface sodium channels by constitutive phosphorylation of ERK
- PKC412, a selective protein kinase C inhibitor, reduces invasion of B16 mouse melanoma cells via attenuation of integrin beta 1 expression
- Role of endogenous thromboxane in hepatic microcirculatory dysfunction during endotoxemia in mice
- Isoforms of vanilloid receptor in skeletal muscle cells
- Arachidonic acid enhances not only the ATPase activity of phosphorylated smooth muscle myosin but also its motor activity
- The two-dimensional (2D) gel electrophoresis of A7R5 cell extract and identification of the spot derived from myosin light chain kinase
- Testosterone regulates expression and function of Kv4.3 encoding A-type K+ channel
- Contribution of intermediate conductance Ca2+ activated K+ channel to membrane excitability of murine urinary bladder smooth muscle cell
- Effects of clenbuterol on expressions of insulin-like growth factors and myogenic satellite cells in rat masseter muscle
- Early apoptosis signal in hindlimb unloading-induced muscle atrophy
- Delphinidin-3-rutinoside (D3R) causes relaxation of the bovine ciliary smooth muscle through excitation of ETB receptors
- Prostaglandin F2.ALPHA. (PGF2.ALPHA.) increases Ca2+ sensitivity of pig iris sphincter muscle
- Gs-triggered, cAMP-independent mechanism(s) is involved in .BETA.-adrenoceptor-mediated relaxation of guinea-pig tracheal smooth muscle
- Rho-kinase interacts myosin II through its PH domain
- Reconstruction and expression of the amino terminal portions of RyR1 in CHO cells
- IL-1.BETA. conduct gastrointestinal motility disorders by decrease in CPI-17 expression in ileal smooth muscle
- Capsaicin-induced decrease in phosphorylation of myosin light chain and in force development in intestines from rats and guinea-pigs
- Reversible cell transformation into spherically proliferating cells isolated from the layer of the small intestinal media
- Intrinsic nervous regulation of vagally-evoked motility of the striated muscles in the rat esophagus
- Mechanical responses to carbachol of intestinal smooth muscle from knockout mice lacking either M2 or M3 muscarinic receptor subtype
- Muscarinic receptor-operated cationic channel current in mouse intestinal smooth muscle cells
- Mitogen-activated protein kinase of p38 regulates sphingosylphosphorylcholine-directed migration of vascular smooth muscle cells by remodeling actin filament
- RNA interference in vascular smooth muscle cells: A crucial role of rhoA in contractility
- Characterization of the smooth muscle relaxant extracted from Physarum polycephalum
- Relative contribution of PKC and rho kinase in the contraction induced by PDBu, high K+ and U46619
- Dysfunction of mouse portal vein in diabetes associates with an alteration of Rho kinase activity
- Endothelial regulation of .ALPHA.2 agonist-induced contraction in rat portal vein
- Histamine-induced contraction in rat blood vessels and synergism with neuropeptide Y
- Later nuclear translocation of NF-.KAPPA.B induced by interleukin 1 involves a tyrosine kinase- and ERK-dependent pathway
- Antiproliferative effects of marine metabolite, stellettamide A, on vascular smooth muscle
- Region-related distribution of prostanoid receptors in non-pregnant porcine uterus
- Roles of endogenous NOS inhibitors and ET-1 for regulating myometrialcontractions during gestation of the rat
- Up-regulation of Rnd in rat and human myometrium during pregnancy
- Pharmacological and molecular analyses of .BETA.-adrenoceptors in guinea-pig esophagus
- Responses to drugs of distal colon isolated from SART (repeatedly cold)-stressed rats
- Expression of recombinant human histidine rich glycoprotein in E. coli
- Accumulation of premature mRNA of GM-CSF receptor common .BETA. subunit in myelodysplastic syndromes
- Possible mechanisms underlying acceleration of proliferation by 15-deoxy-.DELTA.12,14-prostaglandin J2 and the precursors in human leukemia cell lines
- Effect of ATP on the intracellular calcium ion levels of rat erythrocytes
- Effects of amyloid-beta protein (A.BETA.) on Cl--ATPase and Na+/K+-ATPase activities in T lymphocyte (Jurkat cell line)
- Interferon-.GAMMA.-A New Target for prevention of Atheroscleosis-
- Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+-desensitization
- Homozygous transgenic mice overexpressing cardiac NCX1.1 develop cardiac hypertrophy
- Analysis of thromboxane A2 signaling in human vascular smooth muscle by cDNA microarray
- Differential gene regulation by the two beta-adrenergic receptor subtypes in human vascular smooth muscle cell
- Effect of bradykinin on gene expression in human aortic smooth muscle cells
- Torsadogenic action of QT-prolonging drugs, astemizole and haloperidol, assessed by the canine chronic atrioventricular block model
- Assessment of QT interval prolongation in combined use of NM394, an active metabolite of prulifloxacin, and erythromycin
- Mechanical stretch in the early stage after cultivation is a determinant for cell orientation, leading to localization of Cx43 in cardiomyocytes
- RECS1, a novel shear stress-upregulated gene in endothelial cells, suppresses Fas-mediated apoptosis
- Electrophysiological effects of herb medicine, ginsenoside Re, involves nitric oxide
- 17.BETA.-estradiol inhibits TNF-.ALPHA. induced apoptosis via phosphatidylinositol 3-kinase/Akt pathway in vascular endothelial cells
- Protease-activated receptor-mediated myofibril organization in rat cardiomyocytes
- The mitochondrial apoptotic pathway is activated on an in vitro cell culture model of seal-induced cardiac ischemia
- Evaluations of drug-induced proarrhythmic effects in isolated ventricular myocytes of guinea pigs
- Establishment of the methods of quantifying PEDF, a potent antiangiogenic factor
- Shear stress stimulates lipocalin-type prostaglandin D synthase expression through an AP-1 binding site in vascular endothelial cells
- Effects of antiarrhythmic drugs on the HCN4 channels expressed in HEK293 cells
- Lysophosphatidic acid, in the presence of fluid flow, evokes the endothelium-derived thromboxane A2/prostaglandin H2 dependent contraction in mouse aorta
- Mechanisms underlying the reduced relaxation by endothelial nitric oxide in human omental resistance artery in preeclampsia
- Interactive effects of quinolone and macrolide antibiotics on the cardiac action potential parameters
- MODULATION OF HERG CURRENTS BY DRUGS
- Nitric oxide induces apoptosis of adult rat cardiomyocytes via the nitric oxide-cGMP-dependent pathway
- OPC-28326, a Selective Peripheral Vasodilator, Possesses an Angiogenic Property
- Decrease in nitric oxide-production in endothelial cells of mesenteric artery in nitroglycerine-tolerant rabbit
- Electrophysiologic and fluorescence imaging studies on differentiation induced-cardiomyocytes derived from P19CL6 cells in vitro
- Inhibition of Rac1 down-regulates protease-activated receptor (PAR) 1 in the vascular smooth muscle cells
- OPC-28326, a Selective Peripheral Vasodilator, Possesses a Stabilizing Effect on Newly Formed Microvessels
- Homocysteine contributed to angiogenesis through VEGF induction in vitro
- Inhibitory effects of silicone gel sheet in rat solid tumor and angiogenesis
- High throughput hERG assay using the automated patch-clamp system; Optimization of experimental condition
- High throughput hERG assay using the automated patch-clamp system; Comparison to conventional patch clamping
- Nongenomic action of sexo hormone on cardiac electrophysiology
- Experimental arrhythmia model and computer simulated action potential study on Andersen syndrome
- Comparison of the inhibitory effects of PDE inhibitors on the HERG current
- Effects of acidic preconditioning (APC) and Na/Ca exchange (NCE) inhibitors on transient inward current (Iti) during acidosis/reperfusion in guinea-pig ventricular cells
- Blockade of Na+ influx during ischemia as a protective mechanism of diltiazem in ischemic/reperfused heart
- The participation of mitochondrial permeability transition pores (MPTP) against post-ischemic myocardial dysfunction
- Different effects on optical isomers of the 5-HT1A antagonist pyrapyridolol against postischemic myocardial dysfunction in guinea-pig hearts
- Protective effects of the cyclic dipeptides in alcohol beverages against ischemia/reperfusion injury in guinea-pig hearts
- Lysophosphatidylcholine (LPC) transactivates VEGF receptor fetal liver kinase-1/kinase-insert domain-containing receptor (Flk-1/KDR) in HUVEC
- Subcellular localization of mouse Heart-Restricted Leucine-Rich Repeat Protein (HRLRRP)
- Induction of heparanase expression in isoproterenol-induced cardiac hypertrophy in rat
- Roles of the transcriptional factor Sp1 in rat angiotensin AT1A receptor gene expression
- Effects of propofol on action potential and ionic currents in guinea pig cardiomyocytes
- Effects of cibenzoline blocking K-ATP channel on the increase in LV stiffness and the abnormal energy metabolism in underperfused rat hearts
- The mouse sino-atrial node expresses both the type 2 and type 3 Ca2+ release channels/ryanodine receptors
- Etidronate inhibits aortic calcification in renal failure rats
- Roles of Organic Cation Transporters: analysis of aortic constriction model
- Lysophosphatidic acid enhances flow-induced endothelial Ca2+ response in renal artery in situ
- Vascular response of histamine in the mesenteric resistance artery of the rat
- Direct permeating action of neuropeptide Y on the rat aortic endothelial cell monolayer
- Sympathtic Activities in Congenic Rat Strains for the Hypertension-Related Region on Chromosome 1
- Characterization of Novel L-threo-beta-benzyloxyaspartate Derivatives, High Affinity Blockers for the Glutamate Transporters
- Effects of SM-13496, an atypical antipsychotic agent, on MK-801-induced learning deficit in rats
- Clorgyline, a monoamine oxidase A inhibitor, inhibits methamphetamine-induced hyperlocomotion in mice
- The selectively bred high alcohol preference (HAP) and low alcohol preference (LAP) rats differ in activity of histamine-induced phosphoinositide hydrolysis
- The antidepressant-like effect of selegiline on forced swimming test in mice
- Functional modifications of voltage-gated Ca2+ channels by 4-hydroxynonenal, an aldehydic product of membrane lipid peroxidation, in cultured rat dentate granule cells
- Neuroprotection by group II mGluR in primary cultured rat cortical neurons
- Inhibitory effect of nicotine on rat catalepsy induced by haloperidol
- IN VITRO AND IN VIVO PHARMACOLOGICAL PROFILE OF MGS0039, A NOVEL POTENT AND SELECTIVE ANTAGONIST OF GROUP II METABOTROPIC GLUTAMATE RECEPTOR
- Effects of rearing conditions on aging characteristics and pathobiological phenotypes in SAMP10 mice
- Intracerebroventricular injection of microglia protects against focal brain ischemia
- Pharmacological behaviours and MAO in olfactory bulbectomized mice
- Role of GABAA receptors in the substantia nigra pars reticulata and the globus pallidus in rat turning behaviour
- Negative patterning discrimination learning requires the hippocampal formation in rats
- Mechanisms underlying glufosinate-ammonium-induced delayed convulsion
- [18F]TAK-147, a potential radiotracer for imaging acetylcholinesterase: Radiochemical synthesis and binding characteristics in rat brain
- Phosphorylation of Extracellular-regulating Kinase in Newborn Neurons Induced by Transient Global Ischemia in Adult Hippocampus
- Different sensitivities to polyamines in cultured rat brain microglia and astrocytes
- Arc interacts with microtubule/MAP2 (microtubule-associated protein 2) and attenuates MAP2 immunoreactivity in the dendrites
- Effect of leptin on immobility time in the tail suspension test in diabetic mice
- Effect of diabetes on GABAA/benzodiazepine receptor complex in mouse central nervous system
- The dopaminergic system is required for the induction of LTP in the basolateral amygdala-hippocampal dentate gyrus pathway of anesthetized rats
- Endogenous benzodiazepine system is likely to play an inhibitory role in the maintenance of upper airway patency
- Electrophysiological evaluation of stress-related changes in the hippocampal synaptic efficacy in freely moving rats
- The effect of COX inhibitors on the NQs' affinity to GABAA receptor
- Propofol suppresses the responses in hypoglossal nerve activity to hypercapnic-hypoxic stimulation
- Imidazoline receptors partly mediate clonidine-induced antinociception in mice
- Translocation of Bad to mitochondria in the hippocampal CA1 region after transient global ischemia
- Studies on the effects of 1-bromopropane, a substitute for chlorofluorocarbons, on the neurotransmitter receptor functions
- Role of the descending noradrenergic system and spinal .ALPHA.2-adrenoceptors in ameliorating effects of gabapentin on hyperalgesia and tactile allodynia
- Role of median raphe nucleus in serotonergic modulation of anxiety
- Different response to exogenous L-arginine in nitric oxide production between the hippocampus and the striatum of conscious rats
- Amelioration of paresis in brain-injured mice by transplantation of the neurospheres from the adult mouse brain
- Dynamic changes in the rat hippocampal free radicals after transient global ischemia
- Effect of donepezil on group II mGlu receptor agonist- or antagonist-induced amnesia on passive avoidance in mice
- Nociceptive behavior induced by polycationic compounds through the spinal NMDA receptor mechanism
- A novel PIP2 binding activity of .EPSILON.PKC induces neurite outgrowth
- Positive feedback mechanism in the regulation of [Ca2+]i by activation of small-conductance Ca2+-activated K+ channel (SK2) in t-BBEC 117
- Identification and characterization of murine serotonin transporter promoter
- Electroacupuncture-induced anti-morphine action in rats: Differential involvement in analgesia and hyperthermia
- Studies on pain control system (Rept. 20): Involvement of the growth factors in the morphine-induced antinociception
- Basolateral amygdala D2-dopaminergic activity modulates the induction of long-term potentiation in the dentate gyrus of anesthetized rat
- Studies on drug dependence (Rept. 385): Up-regulation of .MU.-opioidergic system following chronic etizolam treatment in mice
- Social isolation stress and brain histamine: No effects of low histamine diet on the stress-induced behaviors in mice
- Chronic treatment of antidepressants participates in seizure sensitization to local anesthetics
- Diclofenac inhibits the proliferation of murine neural stem cells via down-regulation of EGF receptor
- Site of action of the propofol in muscarinic M1 receptor-mediated signal transduction
- Possible neuroregeneration in the hippocampal CA3 subfield after the dentate neurodegeneration in mouse
- Effects of U-50488H on dyskinesia induced by repeated dosing with L-DOPA in MPTP-treated cynomolgus monkeys
- Effects of ifenprodil on discriminative stimulus effects of cocaine in rhesus monkeys
- Involvement of glutamatergic pathway in methamphetamine-induced psychobehavioral deficits and dependence
- Leu-Ile can be a therapeutic tool for methamphetamine-induced dependence
- The 5-HT1A receptor agonist MKC-242 reverses methamphetamine-induced behavioral sensitization in mice
- Effect of the novel peptide prokineticin 2 on locomotor activity and body temperature in mice
- Effects of isatin, selegiline and pramipexole on striatal dopamine and DOPAC levels in a rat model of Parkinson's disease induced by Japanese encephalitis virus
- Attentional performance in a rodent 5-choice serial reaction time task
- Improving effect of .KAPPA.-opioid receptor agonists on the impairment of learning and memory-related behavior in olfactory bulbectomy mice
- Age-related changes in regional cerebral blood flow of the prefrontal cortex in stroke-prone spontaneously hypertensive rats
- Two extracellular matrix (ECM) molecules, fibronectin and laminin, are up-regulated following sciatic nerve injury and they increase P2X4 expression in microglia
- Separate recording of Adelta- and C-fiber mediated withdrawal flexor reflex movements in mice
- Inactivation of endomorphin-1 at the spinal level in mice
- Effect of agmatine on cell viability of cultured rat cortical astrocytes
- Effects of the selective serotonin2C receptor antagonists on antiimmobility effects of antidepressants in mice
- Role of the 5-HT2 receptor subtypes in the serotonin releaser p-chloroamphetamine-induced hyperthermia in mice
- Neurogenesis in the dentate gyrus of adult rat hippocampus is affected by antidepressant treatment and electroconvulsive stimulation
- Pharmacological characterization of channels that mediate glial Ca2+ waves induced by hydrogen sulfide
- Effects of pyrethroids on cholinergic and dopaminergic systems in rat brain
- Excitation of inhibitory interneurons in the hippocampus by extracellular ATP
- Effects of fluvoxamine on immobility time in the forced swimming test: Mice strain differences in sensitivity
- Involvement of glutamate transporters in glutamate-induced suppression of stellation in cultured rat cortical astrocytes
- Influence of a long-term infusion of dexamethasone on 5-HT level in the amygdala and circadian rhythm of activity in freely moving rats
- Presynaptic GABAA receptors modulates glutamatergic synaptic transmission onto hippocampal CA3 pyramidal neurons
- Microglial reactions to facial nerve axotomy in cathepsin S-deficient (CS-/-) mice
- Studies on drug dependence (Rept. 383): Role of the splicing variant-derived mu receptor subtype in the development of physical and psychological dependence on morphine
- Role of SK3 channels in pregnant mouse uterus
- Involvement of supraspinal .ALPHA.2-adrenoceptor blockade in ejaculatory facilitation induced by yohimbine
- Suppression of ghrelin secretion during pregnancy and lactation in the rat
- A novel type of protease-activated receptor (PAR) mediates an enhanced myometrial response to trypsin in sex hormone-treated rats
- Differential expression of L- and T-type Ca channels between longitudinal and circular muscles of the rat myometrium during pregnancy
- Involvement of increased arginase activity in the impaired cavernosal relaxation with aging in the rabbit
- Implication of the mitogen-activated protein kinase pathway in proliferative effect of angiotensin II and endothelin-1 on rabbit gingival fibroblasts
- Protection by pyruvate against oxidative stress in osteoblasts
- Stimulation of [3H]GABA uptake in rat calvarial osteoblasts cultured under hyperglycemic conditions
- Transcriptional regulation of clock genes in cultured chondrogenic ATDC5 cells
- Inhibition of cartilage mineralization by glutamate
- Glycosphingolipids regulate osteoclastgenesis mediated by receptor activator of NF-kB ligand and lipopolysaccharide
- The levels of vitamin K1 and K2 analogues in femur of diabetic rat
- Differential activation of EGF receptors by EGF ligand family in fetal mouse submandibular glands
- Correlation between transverse strength and pQCT factors on mandible and femur in experimental osteoporosis rats
- Mode of anti-inflammatory action of a novel bisphosphonate, TRK-530
- Expression of metallothionein message after phenytoin injection in rat gingiva
- Changes in gene expression on the type II collagen-induced arthritis in rats
- Macrophage migration inhibitory factor inhibits formation of mature osteoclasts
- Upregulation by methotrexate of prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts
- Promotion by D-serine of osteoclastic differentiation in murine pre-osteoclast cell line RAW264.7
- Stimulating effect of taurine on mineralization of osteoblastic cells: Involvement of ERK activation
- Differentiation-inducing factor-1 inhibits cell differentiation in an osteosarcoma cell line SaOS-2
- Calcium-dependent alkaline ATPase activity of an osteoblastic cell
- The calcimimetic compound KRN1493 (cinacalcet hydrochloride) ameliorates osteitis fibrosa in rats with chronic enal insufficiency
- Repeated treatment of valproate produced the decrease in bone mineral density (BMD) in growing rats
- Effect of Pepstatin A in osteoclast
- The inhibitory effects of NF-.KAPPA.B inhibitor on the osteoclast function
- Mizoribine synergistically inhibits osteoclastogenesis in combination with methotrexate
- Impaired collagen-induced arthritis in prostacyclin receptor-deficient mice
- Mechanisms underlying UTP-evoked mechanical allodynia
- Nitric oxide stimulates release of exitatory amino acids through modification of sulfhydryl groups in the trigeminal nucleus caudalis
- Effects of compounds of excitatory amino acid receptor and tachykinin receptor on the withdrawal latency to noxicious heat stimulation in the CCI rats
- Sympathetic nerve regulating thermogenesis of rat brown adipose tissue contains hexametonium-resistant fibers
- Effect of inhaled L-NAME, a non-specific NO synthase inhibitor, on capsaicin-induced coughs in mice and guinea-pigs
- Noradrenaline-induced currents in rat airway ganglion neurons
- Effects of changes of dental occlusal position on the function of heart in guinea pigs
- The effect of methoxamine on the choline metabolism in mice submandibular gland
- Characteristic regulation of exocytotic events by PKC isoforms in single adrenal chromaffin cells
- The role of the cytoplasmic domain of the neural cell adhesion molecule L1 in neurite outgrowth
- Actions of domperidone on the opioid system in isolated guinea-pig ileum: differences between dopamine antagonists on opioid system
- Effects of 8-iso-prostaglandins on the release of noradrenaline from the rat stomach
- Role of K+ channels in M2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach
- Mechanisms of Ca2+ mobilization by purinoceptorstimulation and its receptor subtype in cultured rat myeneric neurones
- Angiotensin II inhibits acetylcholine release via presynaptic AT1 receptors in isolated guinea pig ileum
- Developmental changes in mRNA levels of opioid peptide precursor proteins (OPPPs) and receptors (ORs) in rat stomach and brain
- Autonomic regulation on postural change in SART-stressed rats
- Exercise-induced plasma catecholamines and their methyl metabolites responses in hypertensive patients
- In vivo measurement by [3H]quinuclidinyl benzilate (QNB) of muscarinic receptors (mAChR) in peripheral tissues
- Role of an intracellular cysteine residue in the responsiveness of P2X2 receptor/channel to ATP
- Effects of MAPK inhibitors on catecholamine secretion in bovine adrenal chromaffin cells
- Endocrine disruptors induce a rapid intracellular signaling mediated through mitogen-activated protein kinase in bovine adrenal medullary cells
- Effects of local anesthetics on catecholamine secretion from bovine adrenal chromaffin cells
- Preparation and atomic force microscopy observation of recombinant P2X receptor proteins
- Effects of bleomycin on the polyamine concentration in various tissues of rats
- The effects of grapefruit-juice on the serum concentration of CS-905 in healthy Japanese volunteers
- "Mini Core Battery Test" for safety pharmacology screening
- Possible drug interaction between droxidopa and metal-containing medicines
- The histological study of cultured rat embryos treated by tetrabromobisphenol A in whole embryo cultures
- A role of ionotropic receptors for an excitatory amino acid, L-glutamate in neurogenic pulmonary edema development
- Species difference in hypertriglyceridemia and hepatic drug-metabolizing enzyme induction by amitriptyline
- Caffeine suppresses the expression of the Bcl-2 mRNA in BeWo cell culture and rat placenta
- Anti-cancer effect of shark cartilage
- Pharmacokinetics of midazolam and propofol in sedated state patients during hypothermia
- The involvement of mast cells in the process of wound healing
- Effect of nicotine-induced corticosterone elevation on nitric oxide production in the passive skin Arthus rection in rats
- Preferential T cell differentiation to Th1 subset by PGE2 receptor EP1
- Analysis of Scratching Behavior in a Picryl Chloride Induced Atopic Dermatitis Model in Mice
- Effect of propolis on an atopic dermatitis model in mice
- Effects of apple polyphenols, nutrition supplement, on atopic dermatitis, comparing with FK-506
- The peripherally acting .MU.-opioid receptor agonists SS620 and loperamide inhibit itch-associated response to intradermal substance P in mice
- Changes in expression of P2 receptors induced by retinoic acid in keratinocytes
- Characterization of P2X receptors in cultured normal human epidermal keratinocytes
- Role of Substance P in NC/Nga Mice Model of Atopic Dermatitis
- Roles of CD4- and CD8-positive cells in mosquito allergy-associated itch in mice
- Effect of .BETA.2-adrenergic receptor agonists on ICAM-1, B7 and CD40 expression in MLR
- Effect of PGE2-adrenergic receptor agonists on ICAM-1 and B7 expression in MLR
- Maitake D-Fraction enhances the activation of NK cells in tumor-bearing mice
- Effect of lipopolysaccharide on oral tolerance in mice
- Significance of chymase-dependent transforming growth factor-.BETA. formation on adhesion formation
- Non-clinical safety of new biological drugs for rheumatoid arthritis treatment
- Systemic expression of iNOS in rat carrageenin-induced pleurisy
- Expression of high-affinity choline transporter CHT1 in the human leukemic T cell line MOLT-3
- Enhancement of lymphoid cholinergic activity by PGD2 and its inhibition by ONO-PM-182, a novel DP receptor antagonist in MOLT-3 cells, a human leukemic T cell line
- Nitric Oxide (NO) synthase (NOS) mRNA expression and NO production via muscarinic acetylcholine receptor-mediated pathways in a human leukemic B-cell line
- Detection of .ALPHA.9 and .ALPHA.10 nicotinic acetylcholine receptor subunits in human T and B cells
- Facilitation of lymphocytic cholinergic activity by interaction of T cells with antigen-presenting cells (APCs)
- Cell cycle-dependent expression of chloride channel CIC-5 in HL-60 cells
- Inhibitory effect of olopatadine on nasal rubbing induced by capsaicin in histamine H1 receptor-deficient and mast cell-deficient mice
- Effects of nitric oxide synthase (NOS) inhibitors on plasma NOx and tissue NOS levels in septic organs
- Analysis for effects of a cysLT1R antagonist on allergic airway inflammation
- Cell cycle dependent regulation of small conductance Ca2+-activated K+ channel (SK2) activity in Jurkat T-lymphocytes
- Cathepsin E deficiency induces oxidative stress
- Effect of H4-receptor ligands on IgE mediated histamine release from RBL-2H3 cells
- Inverse agonist action of histamine H1 antagonists
- Pharmacological and crystallographic analyses of HQL-79 as an inhibitor for human hematopoietic prostaglandin D synthase
- Involvement of skin barrier disruption but neither histamine nor serotonin in induction of spontaneous scratching behavior in hairless mice fed with a special diet
- Metabolism of immunosuppressant mycophenolic acid in rats
- Nutritional characteristics of the rat fed a fat- and protein-free diet
- Effects of a long-term administration of oral hypoglycemic agents on the progression of low dose streptozotocin-induced slowly progressive diabetes mellitus in mice
- Role of tetrahydrobiopterin on L-arginine-induced increase in cytosolic Ca2+ concentration in .BETA.-cell
- Possible involvement of hydroxyl radical in H2O2-induced calcium influx through TRPM2 channel
- Effects of transgenic overexpression of pancreatic PACAP on obesity-associated diabetes
- Disappearance of glibenclamide-induced hypoglycemia in Wistar-Kyoto rats
- Biphasic effects of coumestrol, a phytoestrogen, on estrogen receptor-dependent gene expression
- Stimulating effects of growth hormone on the differentiation of bone marrow stem cells in mice
- Contribution of stretch-activated cation channels to hypotonically induced insulin release from rat pancreatic .BETA.-cells
- GABAC receptor-mediated stimulation of prolactin secretion in cultured rat anterior pituitary cells
- Vasopressin stimulates insulin release from islet cells through V1b receptors: A combined pharmacological/knockout approach
- Enhanced expression of COX-II and PGES in IGFBP-rP1/mac25-overexpressed uterine endometrial cells in rats
- Characterization of IGFBP-rP1 expression in rat uterus during early pregnancy
- The Vasopressin V1b receptor critically regulates HPA axis activity under both stress and resting conditions
- Changes in mRNA expressions of UCPs and obesity-related hormones in mice by high-calorie diet
- Essential roles of endogenous tissue plasminogen activator and matrix metalloproteinase on heparin-produced cerebral hemorrhage after cerebral ischemia in mice
- In vivo vascular formation of neural stem cells in the adult mouse brain
- Vascular tube formation of neural stem cells in three-dimensional culture: role of TGF-.BETA.1
- Sensitization of agonist-induced contractions in reconstituted fibers of cultured smooth muscle cells derived from mouse basilar artery
- cDNA cloning of a splice variant of human carnitine transporter (OCTN2) using the database (AssEST) of human gene and ESTs
- Action of Endothelins Relates to Pharmacodynamic Effects of Chronic Cigarette smoke in Spontaneously Hypertensive Rats
- The alteration in MMPs and TIMPs by green tea in STZ-induced diabetic rats
- Role of the vasopression receptor V1a subtype in the development of salt-induced hypertension
- Different responsiveness of adrenergic vasoconstriction among experimental animal models of hypertension
- Aging-related impaired response to a vasoactive peptide (urotensin II) in rat aorta
- Pharmacological actions of sinomenium actum, kampo medicine, on rat aorta
- Cerebral vasospasm attenuated by SR 49059 in a rat model of SAH
- Nicorandil-induced ATP release in endothelial cells depends on increase in intracellular Ca2+ by opening both sarcolemmal and Mitocondrial ATP-sensitive K+ channels
- Pharmacological properties of the Ca2+ influx pathway other than voltage-dependent Ca2+ channels (VDCC) in rat and guinea pig ventricular muscle
- Pharmacological identification of .ALPHA.1L-adrenoceptor in rabbit ear artery
- Regulation of cyclooxygenase-2 expression by prostanoids
- Stimulation of Na+-Ca2+ exchanger by isosorbide dinitrate through Na+-K+ ATPase activation
- Cell density dependence during differentiation from neural stem cells to smooth muscle cells
- Contraction of cerebroparenchymal pericytes and formation of vascular tube
- Neuropeptide Y-mediated potentiation of serotonin-induced contraction in porcine coronary artery
- Mechanisms of impaired relaxation in response to nitric oxide in aortas of salt-loaded stroke-prone spontaneously hypertensive rats
- Upregulation of Vascular Extracellular Superoxide Dismutase in Patients with Acute Coronary Syndromes
- Influence of experimental SAH on effects of COX-1, COX-2 and 5-LOX inhibitors in nicotine-induced endothelium-dependent contraction (EDC) in rat basilar artery
- Real-time imaging of myosin II regulatory light chain phosphorylation using a new protein biosensor
- Augmentation of vascular smooth muscle contractility by endothelium-derived factor(s)
- Possible involvement of nitric oxide on glycosaminoglycan polysulfate-induced vasodilation in the hindpaws of anesthetized rats
- Possible involvement of endothelium and nitric oxide on glycosaminoglycan polysulfate-induced vasorelaxation in isolated rat femoral arteries
- Role of endogeneous factors on induction of late vasospasm after SAH in rat basilar artery
- Alteration in the vascular responses in the isolated basilar artery from streptozotocin-induced diabetic rats
- Diabetes-related changes in adenylyl cyclase expression and decreased relaxation response in rat mesenteric artery
- Diabetes-related changes in cAMP-dependent protein kinase activity decrease relaxation response in rat mesenteric artery
- Possible involvement of PI3-K pathway in attenuated relaxation responses to .ALPHA.2- and .BETA.2-agonists in type I and type II diabetic mice aorta
- The causal relationship between angiotensin II and endothelium-dependent relaxation in streptozotocin-induced diabetic rats
- Mechanism to dilate peripheral resistant vessels with black currant fruits concentrate (BC)
- Microarray analysis of coronary artery smooth muscle cells stimulated by PPAR.ALPHA. and .GAMMA. ligands
- Membrane stretch activates a Ca2+-sensitive, non-selective cation channel via intracellular Ca2+ release in rat cerebral arterial myocyte
- Moment Analysis of Triphasic Vascular Responses to Bradykinin: A Kinetic Consideration
- The long-term administration of poloxamer 407 induces histological changes and attenuates vascular responses to some relaxants in rats
- Platelets aggregation-induced hyperconstriction in atherosclerotic rabbit femoral arteries might be mediated by upregulated 5-HT1B receptors
- Serotonin2A and serotonin1B receptors constrict the newly developed collateral blood vessels in rabbit ischemic hindlimb
- Aging and the effects of red wine polyphenols on coronary circulation in rats
- Vascular effects of polyphenolic substances in rat aorta
- Effects of the elevated level of plasma triglyceride on blood pressure and atherosclerotic changes
- A rapid, simple and sensitive assay for measuring proliferation of vascular smooth muscle cells using bicinchoninic acid (BCA)
- Endothelial NO-dependent and -independent relaxation in mesenteric arteries from endotoxemic rat
- Neuropeptide Y potentiates .ALPHA.1-adorenoceptor-mediated contraction through neuropeptide Y Y1 receptor
- Different response to acidic pH in aorta and tail artery isolated from spontaneously hypertensive rat
- Inhibitory effects of Y-27632 on K+-induced contraction in arterial strips from spontaneously hypertensive rats (SHR)
- Subtype specific change in angiotensin II receptors in mesenteric resistance artery in nitroglycerine-tolerant rabbit
- Arterial relaxation induced by Y-27632 is more evident in K+ contraction than in norepinephrine contraction in spontaneously hypertensive rats (SHR)
- Abnormal baroreceptor reflex in vasopressin V1a-receptor-deficient mice
- Adrenomedullin release in the rat mesenteric resistance artery
- Fluvastatin prevents fetal bovine serum-induced hypertrophy of organ-cultured rat tail arteries
- A study on short-term assessment procedures for the reinforcing effect in self-administration of drugs in the rhesus monkey (2nd report)-assessment of relatively weak reinforcing effect
- Subtype-specific modulation of the channel activity of the NMDA receptor by PSD-95 and GKAP
- The potentiation mechanism of lysophosphatidylcholine to hydroxyl radical generation induced by a neurotoxin, 1-methyl-4-phenylpyridinium ion (MPP+) in rat striatum
- HU210, a synthetic cannabinoid, attenuates MPP+ toxicity in a CB1 receptor-independent manner
- Effect of MS-153, a glutamate transporter activator, on morphine-, methamphetamine- and cocaine-induced conditioned place preference in mice
- Potentiation of antidepressant action by lithium in pharmacological and biochemical study
- Vasopressin V1b receptor Knockout mice exhibit impairment of prepulse inhibition
- Studies on drug Dependence (Rept. 386); Neuronal protein kinase C-dependent activation of spinal cord astrocytes following repeated in vivo administration of morphine
- .ALPHA.7 type nicotinic acetylcholine receptor and prodynorphin mRNA expressions after administration of (-)-nicotine in .BETA.-amyloid peptide (25-35)-treated mice
- Crocetin purified from Gardenia fruit prevents ethanol-induced impairment of long-term potentiation in amygdalo-hippocampal synapses of anesthetized rats
- Characteristics of abnormal behavior induced by starvation stress in mice
- Antidepressive effect of (R)-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride [(-)-BPAP] in animal models of stress disorders
- Central sites of thyrotropin-releasing hormone (TRH) action for elevation of body temperature in arousal stage of hibernating hamster
- Novel cyclophanes intensively inhibit the currents through NMDA receptor channels expressed in Xenopus oocytes
- Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on locomotor activity and spatial learning and memory in SD rats
- Histochemical analysis of mouse brains in the improvement of .BETA.-amyloid-induced amnesia by a potent neuroprotective factor derivative, S14G-Humanin
- Inhibitory effects of isorhynchophylline, an Uncaria rhynchophylla alkaloid, on 5-HT2A receptor function: behaviopharmacological and electrophysiological elucidation
- Involvement of the extracellular signal-regulated kinase in methamphetamine-induced cognitive impairment
- Studies on drug dependence (Rept. 387): Short-term up-regulation of .MU.-opioid receptor functions after repeated administration of the .KAPPA.-opioid receptor agonist in the thalamus of rodents
- The effects of glia-conditioned media on proliferation and differentiation of neural stem cells
- Modulation of the synaptic transmission by adenosine through presynaptic mechanisms in the nucleus of the solitary tract
- Newly synthesized glutamate-trapping compounds selectively inhibit N-methyl-D-aspartate receptor channels
- Glycine responsiveness of neurons in periaqueductal gray (PAG), a micturition center in rat
- Prostaglandin E receptor EP1 regulates dopamine release in vivo
- Neuronal type glutamate transporter eaat3 (eaac1) functions as cysteine transporter in cultured cortical neurons
- Effects of receptor agonists on ATP release from rat brain slices
- The role of spinal nitric oxide in the nociceptive behaviour evoked by intrathecal high-dose morphine
- Presynaptic mechanism underlies large-amplitude miniature EPSCs during P2X receptor activation in the nucleus tractus solitarii
- Altered incorporation of BrdU in dentate granule cells of hippocampus of mice with stress
- Involvements of BDNF and TrkB in LPS-induced neurodeganeration
- Isolation of neural progenitor cells from discrete embryonic brain regions
- Involvement of .KAPPA. opioid system in chronic pain-induced attenuation of the development of physical dependence on morphine in mice
- Development of a model rat of the motor neuron death
- DY-9760e, a calmodulin antagonist, protects neuron from microsphere embolism-induced ischemic brain damage via ininhibition of NO/ONOO- pathway
- cAMP regulates Sema3F-induced growth cone collapse of axons and dendrites of dentate granule cells
- Do DHEAS affect learning and memory that is mediated by NMDA receptor/nNOS pathway in rats?
- Down regulation of ADRG#123 by antidepressant and ECT Neuronal differentiation and neurite outgrowth
- Effect of anti-adhesive glycoprotein SPARC on the threshold of kainic acid-evoked seizures
- Species specific expression of norepinephrine transporter isoforms produced by alternative splicing
- Frizzled-3 protein expression after antidepressant treatment in rat frontal cortex
- Identification and characterization of the murine TRPM4 channel
- Identification of BAP1 as a binding protein for h-ADRG #34
- Screening of changes in gene expression levels of global brain ischemia in rats
- Regulation of immediate early genes transcription by histone modifications in kainate-induced mice
- Alteration of serum/glucocorticoid regulated kinase-1 (sgk-1) gene expression in rat hippocampus after transient global ischemia
- Expression and characerization of a novel antidepressant related gene#102 in rat brain
- The role of COOH terminus in the expression of human norepinephrine transporter
- mRNA expression for histamine H3 receptor isoforms in rat brain
- Evaluation of gene expression in response to sustained magnetism in cultured rat hippocampal neurons
- Expression of AP1 and Tex261 genes in hippocampus after systemic NMDA administration
- Regulation of serotonin transporter activity by its C-terminal region
- Characterization of cytotoxicity by V642I mutant of amyloid precursor protein in primary neurons
- Effects of hypoxia/reoxygenation on the astrocytes from SHRSP and WKY rats
- Involvement of serotonin 2C subtype receptor mRNA editing on neuronal differentiation in NG108-15 cells
- Transcriptome analysis of PACAP-treated rat astrocytes by DNA microarray
- Brain 5-hydroxytryptamine concentrations in cisplatin-induced delayed emesis in rat model
- Activation of spinal 5-HT2A and 5-HT3 receptors by FR143167 inhibits nociceptive response against a mechnical noxious stimulus
- Inhibitory effects of antidepressants on pain-related responses induced by herpes virus inoculation and sural nerve ligation in mice
- c-fos expression in superficial spinal dorsal horn associated with spontaneous itch-related behavior in rodents with dry skin
- The prediction of characteristics of the antipsychotic candidate by receptogram and behavioral pharmacology
- Brake reaction time during actual car-driving examination: comparative study of fexofenadine and hydroxyzine
- Molecular mechanisms of associative learning impairments in chronic phencyclidine-treated mice
- Effects of a TRPV4 agonist, 4.ALPHA.-phorbol 12,13-didecanoate, microinjected into the lateral cerebroventricle on drinking behavior
- Testosterone is required for male recognizing fertile female by olfaction
- The role of GABA and glutamate neurons in general anesthetic action
- Response of the rat hypothalamic histamine release to feeding-related peptides: orexins, neuropeptide Y, and ghrelin
- Behavioral Pharmacology of Plant-derived Substances (12): Effects of Repeated Administrations of Menthol and Dopamine Related Drugs on Ambulation in Mice
- Contribution of dopamine D4 receptor to impairment of prepulse inhibition in mice sensitized with methamphetamine.
- Analysis of differentially expressed genes in the brain of aged V642I-APP knock-in mice with deteriorated latent learning memory
- Effects of hypnotics, zolpidem and triazolam, on respiration during sleep in mice
- Effects of ryanodine on membrane potential trajectories of bulbar respiratory neurons in decerebrate cats
- Allopregnanolone modulates the chemoreceptor reflex by acting on GABAA recetors in the commissural subnucleus of the nucleus tractus solitarius in rats
- Fructose plus Cu2+ potently stimulates 8-hydroxydeoxyguanosine formation in calf thymus DNA
- Is there a novel ion channel GABA receptor subunit in the human genome?
- Enzaymatic production of RNAi library and selection of efficient RNAi constructs
- Differential regulation of stress response genes and transcription factors by NO donors
- Structural and functional characterization of Nudix motif in TRPM2 channel
- Identification of a Neutral Amino Acid Transporter corresponding to System L2
- Identification of mouse TRAD/RAD51L3 transcripts and its genomic structure
- Identification of a novel system y+ cationic amino acid transporter expressed in placenta
- Curcumin activates antioxidant response element-mediated transcription via p38 MAP kinase pathway
- Temporal imaging of fluctuations in gene expression
- Regulation of gicerin gene by NGF
- Contribution of the C-terminal domain to the functional regulation of melanin-concentrating hormone receptor 1
- Biochemical Characterization of Recombinant Physarum Annexin
- Manipulation of alternative splicing by a novel inhibitor of Clks
- Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions
- Production of the chimaeric mice carrying targeting disruption in the Clcn5 gene
- Alterations of mRNA levels after chronic administration with antipsychotic drugs in mice
- Identification of Toll-like receptor 3 mRNA from rat total blood
- Molecular characterization of a novel phospholipase D generating anandamide, an endogenous marijuana-like substance
- Importance of pepsin in the pathogenesis of acid reflux esophagitis
- Suppression of bleomycin-induced lung fibrosis by 15-deoxy-.DELTA.12,14-prostaglandin J2
- Pharmacological studies on the respiratory tract (Rept.259): In vivo measurement of vascular response of nasal septal mucosa in guinea pigs
- Effects of bronchodilators on changes in cigarette smoke-exposed guinea pigs
- Lung metastasis of cancer cells suppressed in p38A mitogen-activated protein kinase knockout mice
- Activation of myelin basic protein (MBP) kinase during apoptosis of Jurkat & HL-60 cells
- Establishment of novel monoclonal antiobodies against bronchotracheal mucin
- TGF-.BETA.1 enhances the fibroblast-mediated collagen gel contraction but not the isometric tension development
- Involvement of Rho kinase in PAR-2-mediated increase in neutrophil adhesion to human lung epithelial cells
- Effects of hypnotics on the citric acid-induced laryngeal reflexes in guinea pigs
- Similarity and difference in hypersensitivity reactions induced by paclitaxel and radiographic contrast medium
- Sensory nerve peptides are involved in paclitaxel hypersensitivity
- Fictive cough evoked by localized electrical stimulation of the NTS in guinea pigs
- Mechanisms for relaxation caused by PAR-2 and PAR-1 activation in mouse airway smooth muscle
- Effects of Saiboku-to and Saiko-ka-ryukotsu-borei-to, Japanese Kampo medicines, on theophylline-induced bronchodilation in guinea-pigs
- Effect of jasmone on the tracheal smooth muscle
- Protein kinase A inhibits RhoA-induced migration of airway smooth muscle cells
- Pharmacological studies on the respiratory tract (Rept. 258): Development of airway hyperresponsiveness by chronic exposure to cigarette smoke-Strain differences in rats-
- Pharmacological studies on the respiratory tract (Rept. 260): Identification of transcription factors participating in bronchial smooth muscle hyperresponsiveness
- .BETA.2-Adrenergic receptor activation-induced histamine H1 receptor down-regulation
- Brainstem projection sites of the superior laryngeal nerve in guinea pigs
- Activation of protein kinase C isozymes by PAR-2 stimulation in guinea pig tracheal epithelial cells
- Effect of glycyrrhizin on late asthmatic responses induced by antigen inhalation in guinea pigs
- Anti-ulcer drug irsogladine prevents monochloramine-induced gastric mucosal lesions by reversal of the decrease in mucosal blood flow due to the disturbance of NO synthesis in rats
- Suppression of superoxide production in human neutrophils through inhibition of PDE4: An implication for a role of cAMP in anti-ulcer action of irsogladine
- Protective effect of rebamipide on dextran sulfate sodium-induced colitis in rats
- Dual action of prostaglandin E2 on gastric acid secretion through different EP receptor subtypes in rats
- Irritative Action of alcoholic beverages in Rat Stomachs
- Lactulose ameliorates dextran sodium sulphate (DSS)-induced colitis in rats
- An agonist for the prostaglandin E2 receptor subtype EP4 protects the liver from carbon tetrachloride-induced acute injury
- Chymase positive mast cells in human gastric cancer
- Effect of dehydroepiandrosterone on cytochrome P450 expression in rat liver
- Effect of dehydroepiandresterone on mRNA expression of several transporters in rat small intestine
- The effect of ursodeoxycholic acid on glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes
- Activation of liver microsomal glutathione S-transferase in galactosamine-induced oxidative stress of rats
- Effects of Calcium concentration and pH on Difructose anhydride III enhance Calcium absorption from Rat Small and Large Intestinal Epithelium in vitro
- Involvement of vagus nerve on H. pylori infection in Monglian gerbils
- Histamine Induced Gastric Mucosal Lesions in Rats with Partial Gastric Vascular Occlusion
- Involvement of mast cells in the GaIN/LPS-induced mouse liver injury
- Effects of Lanthanum and Novel Chelating Resin on Treatment of Hyperphosphateamis
- Mild stress protects against gastric ulceration induced by severe stress in rats: Roles of COX-1 and COX-2
- Modulation of voltage-dependent Ba2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent mechanisms
- Involvement of the downregulation of CPI-17 in functional changes in distal colon from experimental colitis model mouse
- Properties of cultured cells from gastrointestinal stromal tumors (GIST)
- Development of intestinal but not gastric lesions induced by rofecoxib in the presence of a low dose of indomethacin
- Mechanisms for modulation of mouse gastrointestinal motility caused by protease-activated receptor (PAR)-1 and PAR-2 activation
- Gastroprokinetic action of growth hormone secretagogue receptor (GHS-R) agonists in mice
- Prostaglandin E2 suppresses myoelectrical activity of gastric smooth muscle and protects gastric mucosal injury from ethanol
- Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via tachykinin NK2/NK3 receptors
- Receptor subtype specific activation of the rat visceral vagal afferent fibers to serotonin
- In vivo real-time measurement of nitric oxide generation in the rat gastrointestinal tract
- Inhibition of gastric acid secretion by the stimulation of vanilloid receptor subtype 1 in isolated mouse stomach
- Protective effect of pranlukast on indomethacin-induced small intestinal lesions in rats
- Dynamics of muscularis macrophage populations during intestinal inflammation in TNBS-induced Crohn's model rat
- Mechanism of action for aspirin to inhibit overactive bladder in rats
- The enhancement of mitochondrial free radical generation and PKC.DELTA. in CER-induced nephrotoxicity in rats
- Prostaglandin E2 Suppresses Renal Fibrosis via its Receptor Subtype EP4
- The effects of serotonin related compounds on the urinary bladder motility in conscious rats
- cAMP attenuates the production of fibronectin in glomeruli of nephritic rats
- Processing of Aggregated Protein in the Glomeruli in Genetically diabetic Mice
- Gender and age difference of the expression of mouse urate transporter (mURAT1)
- Role of nitric oxide in the renal ischemic preconditioning
- Role of nitric oxide in the progression of ischemic acute renal failure in rats
- Involvement of NO in the protective effect of 17.BETA.-estradiol on ischemic acute renal failure
- A new method for measurements of frequency of urination of rats under conscious and unrestricted conditions by cystometry
- Effect of hyperlipidemia on renal tubulo-interstitial fibrosis in diabetic KK-Ay mice
- Characterization of a voltage-driven organic anion transporter OATV1: the exit path of organic anion at the apical membrane of renal proximal tubule
- Cloning and characterization of a novel rat organic anion transporter (OAT5) at the apical side of renal proximal tubules
- Polycystin-L is a voltage dependent and non-selective cation channel
- Activation of A kinase attenuates cisplatin-induced renal tubular cell injury by inhibiting the induction of TNF-.ALPHA.
- Human organic cation transporter 3 (hOCT3) mediates the renal transport of antiarrythmic drugs
- Role of PKC in contraction of human prostatic stromal cells
- Attenuated responses of Cyclooxygenase-2 expression is involved in retarded processing of aggregated protein in diabetic glomeruli
- Effects of U-37883A on BKCa and KATP channels in pig urethra
- Effects of NK082411 on the micturition
- Changes in endogenous NOS inhibitors in the female rabbit urethra following estrogen supplementation
- Modulation of NO production by arginase in the rabbit lower urinary tract
- The effect of Propiverine hydrochloride in a canine urinary frequency model associated with bladder hyperactivity
- Tubuloglomerular feedback (TGF) response in Dahl salt-sensitive hypertensive rats
- Proarrhythmic effects of the agents which delay repolarization in isoflurane anesthetized dogs
- In vivo electropharmacological effects of a class III antiarrhythmic drug dlsotalol assessed using halothane anesthetized canine model
- Hemodynamic effects of the venom of Chiropsalmus quadrigatus (Habu-kurage) in rats
- Pravastatin inhibits arrhythmias and infarct size induced by coronary artery ischemia/reperfusion in anesthetized rats
- Evaluation of drugs inducing QT-interval prolongation by ECG recorded from the isolated guinea-pig heart perfused with the Langendorff's method
- Effects of the prostanoids on blood pressure and heart rate: an analysis using mice lacking the prostanoid receptors
- Regulation of eNOS expression and AMPK-mediated phosphorylation in aortas of SHRSP
- Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor
- Pharmacological characterization of YM598, a selective endothelin ETA receptor antagonist
- Alleviation of hypoxia/reoxygenation (H/R)-induced myocardial injury in the sensitized guinea-pig heart
- Effects of osmotic pressure and cooling on the arginine amidase activities released from rabbit arteries
- Opening of mitochondrial Ca2+-activated K+ channels attenuates the Ca2+ overload in mitochondria
- Preventive effects of fluvastatin on oxidative modification of LDL via peroxynitrite
- Upregulation of angiotensin II type-2 receptor in rat aorta by pressure-overload
- Proteome analysis of acute heart failure with autoimmune myocarditis in the rat
- Molecular mechanisms of azimilide on IKr and IKs
- Taurine suppressed cardiac hypertrophy induced by endothelin-1 in rat neonatal cardiac myocytes
- Investigation on in vivo models for evaluating QT prolongation induced by drugs possessing pro-arrhythmic risk
- Prediction of drug-induced QT prolongation using halothane-anesthetized canine model: Comparison of risperidone and olanzapine
- Verrucotoxin (a venom of stonefish) acts as a .BETA.-adrenoceptor agonist in guinea-pig ventricular myocytes
- Feasibility of Use of High-cholesterol-fed Miniature Pigs as Arteriosclerosis Models
- Cilostazol Improves Superoxide-induced Deterioration of Endothelium-dependent Relaxation in Rats
- Plasma concentrations of class I antiarrhythmic drugs and their clinical effects
- Increase in hepatic mRNA expression of fibrinogen in spontaneously hypertensive and hyperlipidemic rats (SHHRs)
- Role of endothelin ETA and ETB receptor in the ischemia/reperfusion-induced cardiac dysfunction and norepinephrine overflow of isolated rat hearts
- Induction of atherogenesis in apolipoprotein E-deficient mice through superoxide production under hypoxia
- Characterization of the voltage-dependent .BETA.3 subunit in murine cardiac function
- Role of the sodium-calcium exchanger in excitation-contraction coupling of mouse myocardium
- Point mutations that alter coupling between the voltage sensor and the activation gate of HERG channel
- Muscarinic receptor-mediated aggravation of aconitine-induced arrhythmia in isolated guinea pig myocardium
- Possible involvement of hydroxyl radical on the stimulation of tetrahydrobiopterin synthesis by H2O2 and peroxynitrite in vascular endothelial cells
- Inotropic effects of muscarinic stimulation on ventricular myocardium from chick and quail
- Expression and characterization of rabbit endothelin receptors
- Reciprocal changes in EDHF- and NO-system in the female rat mesenteric artery following ovariectomy
- Effects of E-4031 on the currents of Xenopus oocytes expressing HERG and KvLQT1/minK channels
- Effect of Thioridazine, Beprozil and Pimozide on monophasic action potential (MAP), effective refractory period (ERP), and terminal repolarization period (TRP)
- Significance of combined therapy of aspirin and atolvastatin after coronary artery bypass grafting (CABG)
- Quantitative assessment of myocardial blood flow induced by adenosine and CGS-21680 with H215O PET in miniature pigs
- Characterization of angiotensin receptors in isolated porcine basilar artery by functional and radioligand binding studies
- Effects of acute oral amiodarone on coronary ligation/reperfusion-induced arrhythmias in dogs
- The simulation study of the voltage-dependent regulation of G protein cycle in cardiac myocytes
- Identification of nifekalant-binding sites in a HERG channel
- Prostacyclin increases blood flow of the fundus in tetrodotoxin-treated rats
- Contractile response to tetrahydrobiopterin in aortic ring preparations isolated from normotensive and spontaneously hypertensive rats
- Detection of Sodium Channel Block in Action Potential
- Hypercholesterolemia increases epoxyeicosatrienoic acids (EETs), cytochrom P-450 methabolites of arachidonic acids, in rabbit renal artery; Effect of pioglitazone on it
- Post-ischemic administration of DY-9760e, a novel calmodulin antagonist, ameliorated ischemia/reperfusion injury in the rat heart
- Apoptosis Signal-Regulating Kinase 1 plays a pivotal role in Angiotensin II-Induced Cardiac Remodeling
- The vasopressin V1a receptor is critically involved in the regulation of blood pressure
- Sir2.ALPHA., an NAD-dependent histone deacetylase, is predominantly expressed in the embryonic heart and brain in a developmentally regulated manner
- Regulation of dendritic spine morphology by cell adhesion molecules
- Propylene glycol increases cytosolic free calcium in rat cerebrocortical synaptosomes
- Inactivation of integrin-linked Kinase induces aberrant tau phosphorylation via sustained activation of glycogen synthase kinase 3.BETA. in N1E-115 neuroblastoma cells
- A novel potent radical scavenger, FR210575, prevents neuronal cell death in cultured primary neurons and attenuates brain injury following focal ischemia in rats
- Down-regulation of immediate early gene Egr-1 expression in rat C6 glioma cells exposed to high salt culture conditions: Possible relation to cell proleferation
- Thapsigargin-induced apoptosis in human neuroblastoma SH-SY5Y cells
- Effect of (-)-BPAP on the expression of neurotrophins and their receptors in mesencephalic slice cultures
- The .ETA. and .MU. isoforms of protein kinase C are involved in stellation of cultured rat cortical astrocytes
- Increased expression of HSP105 by inhibition of ubiquitin-proteasome pathway in SH-SY5Y cells
- Phosphorylation of extracellular-regulating kinase in newly generated neurons induced by NMDA receptor antagonist in the hippocampus of adult rats
- Modulation by experimental ischemia of proton-induced currents in rat substantia nigra neurons
- Morphological change of microglia in the phagocytosis of amyloid-.BETA.
- Protection of oxidative-stress-induced astrocytic damage by ATP via P2Y1 receptors
- The differential effects of Buckwheat and Kudingcha polyphenols against neuronal damage in cultured hippocampal neurons and spatial memory impairment induced by scopolamine
- Characterization of drebrin A in vitro
- Iron blocks dopamine neurotoxicity by accelerating conversion of aminochrome into melanin
- Role of endogenous D-serine on neuronal death by N-methyl-D-aspartate or simulated ischemia in in vitro rat cerebrocortical slices
- EGF and FGF signaling on stem/progenitor cells expression within the human embryonic neurospheres
- Neuronal induction effect of all-trans retinoic acid on human neural stem/progenitor cells (NSPCs)
- Regulation of the affinity of histamine for histamine H1 receptors by the ionomycin-induced increase in intracellular Ca2+ concentration in human U373 MG astrocytoma cells
- TACHYKININS MODULATE SLOW OSCILLATORY BURSTS IN THE RAT AMYGDALA GABA SYNAPSE
- FK506 potentiates NGF-induced neurite outgrowth via Ras/Raf/MAP kinase pathway
- Studies on drug dependence (Rept. 384) Role of astrocytic protein kinase C in the development of sensitization to methamphetamine
- Cannabinoid-induced apoptosis in 1321N1 human astrocytoma cells
- CAD, 5,19-cyclo-9.BETA.,10.XI.-androstane-3,17-dione, as a potentiator of neurotrophic factor biosynthesis in glial cells mediated via protein kinase C-.DELTA. and .EPSILON.
- Neuroprotective effects of .ALPHA.-tocopherol transfer protein (.ALPHA.-TTP) on oxidative stress
- Cyclosporine A (CsA) aggravates electroshock (ECS)-induced convulsions in mice with a transient middle cerebral artery occlusion
- Mechanisms of estrogen-induced elevation of PKA activity in immortalized hippocampal neurons
- Features of tanycytes in response to extracellular Na+ changes observed in the mouse
- Studies on Alzheimer's disease (Rept. 9): Effect of amyloid .BETA. protein on cell viability, morphology and ERK phosphorylation in cultured rat hippocampal and striatal astrocytes
- Synaptic accumulation of Vesl-1S/Homer-1a conjugated with Venus protein in neuronal dendrites
- Effects of agonist of three dopamine (DA) receptor types on the extracellular concentrations of DA in rat striatum
- Effect of sodium nitroprusside on intracellular Ca2+ metabolism in cultured astrocytes
- In vivo release of endogenous opioid peptides (EOPs) by chemicals
- Clinical trial of quinacrine in patients with Creulzfeldt-Jakob disease and experimental evidences for its uptake and efflux at the blood-brain barrier (BBB)
- Effect of minocycline on the development of morphine antinociceptive tolerance in mice
- Cyclosporin A transports across the pathologically reconstituted blood-brain barrier (BBB) after an exposure to hypoxic condition
- An in vitro model of the blood-brain barrier with human peripheral microvascular endothelial cells
- Pre- and post-synaptic roles of cyclic ADP-ribose in dopaminergic neurotransmission in rodent Caudate Putamen (1)
- Altered responsiveness to nicotine during cultured neuronal maturation
- Vitamin E derivatives inhibit the production of abnormal prion protein in vitro
- Screening study of new potent non-immunosuppressive immunophilin ligands (NI-IPLs) based on the molecular basis of neuroprotective properties of existent NI-IPLs
- Characterization of a novel Pur.ALPHA. binding protein in mouse brain
- Protein kinase C-.GAMMA. involvement in the insulin-mediated inhibition of neuronal necrosis in the in vitro ischemic model
- Membrane-associated BAD/PKA complex: a possible anti-apoptotic signal transducer
- .GAMMA.-Hydroxybutyric acid, unlike .GAMMA.-aminobutyric acid, does not stimulate Gi/Go proteins in rat brain membranes
- Fluoxetine-elicited increase of brain allopregnanolone level is caused by inhibition of allopregnanolone metabolism catalyzed by CYP2D
- Potentiation of NMDA agonist-induced neuronal death by .BETA.-amyloid in rat organotypic hippocampal slice cultures: evidence for multiple cell death pathways
- Roles of the intraneuronal Cl- concentration and tyrosine phosphorylated proteins in amyloid .BETA. protein-induced aggravation of glutamate neurotoxicity
- Amyloid .BETA. proteins inhibit recombinant human type II phosphatidylinositol 4-kinase .ALPHA. activity
- F1, a natural compound from citrus fruits, induces neuronal differentiation by activating a cAMP-dependent signaling pathway in PC12D cells
- Effect of ER stress on mitochondrial membrane potential in cultured rat astrocytes
- Visualization of muscarinic acetylcholine receptor using post-photoaffinity labeling modification (P-PLAM) method in cells
- Internalization and recycling of muscarinic acetylcholine receptor M2 and M4 subtypes: the role of the third intracellular loop (I3 loop)
- Enhancement of long-term potentiation in hippocampal slices of transgenic mice expressed GFP-drebrin A
- Neuroprotective effects of SUN N8075 in a monkey model of stroke
- Protective effects of SUN N8075 on cerebral infarction in rats subjected to permanent middle cerebral artery occlusion (pMCAO): A study of therapeutic time window (TTW)
- FK419, a novel non-peptide antagonist of platelet glycoprotein GPIIb/IIIa, is neuroprotective in a guinea pig focal cerebral ischemia model with minimal risk of cerebral hemorrhage
- EFFECT OF TS-011, AN INHIBITOR OF THE SYNTHESIS OF 20-HETE, ON CEREBRAL BLOOD FLOW AFTER SUBARACHNOID HEMORRHAGE (SAH) IN RATS
- Effect of TS-011, an inhibitor of the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE), on infarct size in models of ischemic stoke
- The role for cental prostalandin E2 receptors in cardiovascular regulation in anesthetized rats
- Effects of hydrocortisone on cerebral salt wasting after subarachnoid hemorrhage in rats
- Novel antioxidant (3): Pharmacological profiles of A-3877, a new drug for acute stroke
- Effects of antihypertensive drugs on the ischemia-related neuronal death in SHRSP
- Antihypertensive and neuroprotective effects of astaxanthin in SHR-SP
- Effects of vasoactive factors on intracellular Ca2+ levels and cytoskeletal actin organization in mouse brain microvascular endothelial cell line, bEnd.3
- Roles of androgen and estrogen on short-term memory deficit in an animal model of attention-deficit/hyperactivity disorder
- A comparative study of D1-like dopamine receptor agonists and transduction mechanisms on orofacial movements of mice
- Endovascular Approach to Transient Occlusion of the MCA in Non-Human Primates: Characterizing the Evolution of Acute Ischemic Stroke by MRI
- Basolateral Amygdala Modulates Hippocampal Synaptic Metaplasticity
- Disruption of calcium homeostasis caused by Alzheimer's .BETA.-amyloid protein and prion protein
- Opioid substrates seen from molecular form
- The acute and chronic effects of antihistamines on methamphetamine-induced psychomotor activation in rats
- Antidepressant-like effects of the metabolites of orally administered Magnolia officinalis extract in rats and man
- Centrally administered vasopressin elicites adrenal noradreline release by brain thromboxane A2-mediated mechanisms in rats
- Centrally administered bombesin elicites adrenal noradrenaline release by brain thromboxane A2-mediated mechanisms in rats
- The characterization of biosynthesis and secretion of CNP in rat cultured astrocytes
- Distinct effects between dehydroepiandrosterone and its sulfate ester on voltage-gated sodium channels
- The mechanisms underlying the down-regulation by estrogens of L-glutamate transporter of astrocytes
- Antiobesity Effect of YM348, a Novel 5-HT2C Receptor Agonist, in Zucker Rats
- Thermogenic Effect of YM348, a Novel 5-HT2C Receptor Agonist, in Rats
- The effect of suramin on mechanical allodynia developing in melanoma-implanted mice
- Decreased expression of glial cell line-derived neurotrophic factor signaling in neuropathic pain state
- G.BETA..GAMMA. subunits are involved in the diverse signaling of Gi/o-coupled receptors
- Distribution of central and peripheral muscarinic receptor subtypes
- Pre-clinical evaluations of novel peripheral benzodiazepine receptor PET tracer [11C]DAA1106
- Up-regulation of microglial P2X4 receptor expression by retinoic acid
- The mechanisms of bacterial endotoxin-induced endoplasmic reticulum stress response
- Mechanism of neuroprotection mediated by P2X7 receptor-activated microglia
- Light-induced protein phosphorylation and c-Fos expression in the suprachiasmatic nucleus in mice lacking PACAP
- Dopaminergic and cholinergic interactions in the nucleus accumbens shell in rat turning behaviour
1 - Three-Finger .ALPHA.-Neurotoxins and the Nicotinic Acetylcholine Receptor, Forty Years On
- YC-1, a Nitric Oxide-Independent Activator of Soluble Guanylate Cyclase, Inhibits the Spontaneous Contractions of Isolated Pregnant Rat Myometrium
- A Novel Method to Quantify Calcium Response Pattern and Oscillation Using Fura2 and Acridine Orange
- Effect of Nicotine-Induced Corticosterone Elevation on Nitric Oxide Production in the Passive Skin Arthus Reaction in Rats
- Detrimental Role of Corticotropin-Releasing Factor on the Decrease of CA1 Field Potential Induced by In Vitro Ischemia in Rat Hippocampal Slices
- The Action Mode of Lysophosphatidylcholine in Human Monocytes
- Estrogenic Effects of Pueraria mirifica on the Menstrual Cycle and Hormone-Related Ovarian Functions in Cyclic Female Cynomolgus Monkeys
- Effect of Ethanol Extracts of Three Chinese Medicinal Plants With Anti-diarrheal Properties on Ion Transport of the Rat Intestinal Epithelia
- Sustained Plasma Fibrinogen Elevation in Subtotal Nephrectomized Rats: Effect of Cilazapril, an Angiotensin-Converting Enzyme Inhibitor
- 5-HT3-Receptor Antagonist Inhibits Visceral Pain Differently in Chemical and Mechanical Stimuli in Rats
- Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
- The Inhibitory Effects of Aqueous Extract of Magnolia officinalis on Human Mesangial Cell Proliferation by Regulation of Platelet-Derived Growth Factor-BB and Transforming Growth Factor-.BETA.1 Expression
2 - ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Purinergic Receptor Complex: Generating Adenine Nucleotide-Sensitive Adenosine Receptors
- ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Receptor Activation by ATP Through Rapid and Localized Generation of Adenosine by Ecto-nucleotidases
- ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Stimulates Glutamate Release From Astrocytes via A2a Adenosine Receptors
- ATP- and Adenosine-Mediated Signaling in the Central Nervous System: The Role of Extracellular ATP in Hippocampal Long-Term Potentiation
- ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Synaptic Purinoceptors: the Stage for ATP to Play Its "Dual-Role"
- ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Chronic Pain and Microglia: Involvement of the ATP Receptor P2X4
- Different Prostanoids Are Involved in Bradykinin-Induced Endothelium-Dependent and -Independent Vasoconstriction in Rat Mesenteric Resistance Arteries
- Effects of 4-Ethylamino-2-butynyl(2-cyclohexyl-2-phenyl)glycolate Hydrochloride, a Metabolite of Oxybutynin, on Bladder Specimens and Rhythmic Bladder Contraction in Rats in Comparison With Oxybutynin
- In Vitro Effects of Astaxanthin Combined With Ginkgolide B on T Lymphocyte Activation in Peripheral Blood Mononuclear Cells From Asthmatic Subjects
- Endogenous GABA Does Not Mediate the Inhibitory Effects of Gabapentin on Spinal Reflexes in Rats
- Effects of Tegaserod on Ileal Peristalsis of Guinea Pig In Vitro
- Involvement of Locus Coeruleus Noradrenergic Neurons in Supraspinal Antinociception by .ALPHA.,.BETA.-Methylene-ATP in Rats
- Possible Involvement of Opioidergic and Serotonergic Mechanisms in Antinociceptive Effect of Paroxetine in Acute Pain
- p53-Mediated Cell Cycle Arrest and Apoptosis Induced by Shikonin via a Caspase-9-Dependent Mechanism in Human Malignant Melanoma A375-S2 Cells
- Antitumor Activity and Antioxidant Status of Caesalpinia bonducella Against Ehrlich Ascites Carcinoma in Swiss Albino Mice
- The Diuretic Effect of Sairei-to Is Mediated by Nitric Oxide Production in Pentobarbital-Anesthetized Rats
- Cyclooxygenase Inhibitors Attenuate Augmented Glutamate Release in Organum Vasculosum Laminae Terminalis and Fever Induced by Staphylococcal Enterotoxin A
- Interactions of Human- and Rat-Organic Anion Transporters With Pravastatin and Cimetidine
- Intracerebroventricular Injection of Microglia Protects Against Focal Brain Ischemia
- Repeated Treatment With the Traditional Medicine Unsei-in Inhibits Substance P-Induced Itch-Associated Responses Through Downregulation of the Expression of Nitric Oxide Synthase 1 in Mice
- Characterization of GABAB Receptor in the Human Colon
3 - Glutamate Signaling System in Bone
- Hypoxia-Inducible Factor 1-Related Diseases and Prospective Therapeutic Tools
- Protein Kinase C Activation by Helicobacter pylori in Human Gastric Epithelial Cells Limits Interleukin-8 Production Through Suppression of Extracellular Signal-Regulated Kinase
- Role of Pharmacokinetic Effects in the Potentiation of Morphine Analgesia by L-Type Calcium Channel Blockers in Mice
- Electroencephalographic Properties of Zaleplon, a Non-Benzodiazepine Sedative/Hypnotic, in Rats
- The Inhibitory Mechanism of YC-1, a Benzyl Indazole, on Smooth Muscle Cell Proliferation: an In Vitro and In Vivo Study
- Possible Involvement of p38 in Mechanisms Underlying Acceleration of Proliferation by 15-Deoxy-.DELTA.12,14-prostaglandin J2 and the Precursors in Leukemia Cell Line THP-1
- The Effects of Selective Serotonin-Reuptake Inhibitor on Visual Evoked Potential in Rats
- Modulation of Capsaicin-Evoked Visceral Pain and Referred Hyperalgesia by Protease-Activated Receptors 1 and 2
- Changes of Brain Endothelin Levels and Peripheral Endothelin Receptors by Chronic Cigarette Smoke in Spontaneously Hypertensive Rats
- Human Organic Anion Transporter 4 Is a Renal Apical Organic Anion/Dicarboxylate Exchanger in the Proximal Tubules
- Disability of Development of Tolerance to Morphine and U-50,488H, a Selective .KAPPA.-Opioid Receptor Agonist, in Neuropathic Pain Model Mice
- Effects of Sasanquasaponin on Ischemia and Reperfusion Injury in Mouse Hearts
- Curcumin Suppresses Lipopolysaccharide-Induced Cyclooxygenase-2 Expression by Inhibiting Activator Protein 1 and Nuclear Factor .KAPPA.B Bindings in BV2 Microglial Cells
- The Phenoxazine Derivative Phx-1 Suppresses IgE-Mediated Degranulation in Rat Basophilic Leukemia RBL-2H3 Cells
- Nicotinic Acetylcholine Receptor .ALPHA.7 Subunit Mediates Migration of Vascular Smooth Muscle Cells Toward Nicotine
4 - .BETA.1-Subunit of MaxiK Channel in Smooth Muscle: a Key Molecule Which Tunes Muscle Mechanical Activity
- The Pharmacological Actions of Nicotine on the Gastrointestinal Tract
- Chung-Yeul-Gue-Soup-Sa-Gan-Tang, Traditional Korean Medicine, Enhances CD4+ T Cell Activities and Modulates Th1/Th2 Lineage Development
- Characterization of GABAB Receptors Involved in Inhibition of Motility Associated With Acetylcholine Release in the Dog Small Intestine: Possible Existence of a Heterodimer of GABAB1 and GABAB2 Subunits
- Mechanism of Human Urotensin II-Induced Contraction in Rat Aorta
- Leukocyte Recruitment to Peritoneal Cavity of Rats Following Formalin Injection: Role of Tachykinin Receptors
- Protective Effect of Buckwheat Polyphenols Against Long-Lasting Impairment of Spatial Memory Associated With Hippocampal Neuronal Damage in Rats Subjected to Repeated Cerebral Ischemia
- Simvastatin, an HMG-CoA Reductase Inhibitor, Reduced the Expression of Matrix Metalloproteinase-9 (Gelatinase B) in Osteoblastic Cells and HT1080 Fibrosarcoma Cells
- Identification of Amino Acid Residues Responsible for Agonist-Induced Down-Regulation of Histamine H1 Receptors
- Effect of Thyroid Hormone on CYP19 Expression in Ovarian Granulosa Cells From Gonadotropin-Treated Immature Rats
- Antidiuretic Effects of a Novel Nonpeptide Vasopressin V2-Receptor Agonist, OPC-51803, Administered Orally to Dogs
- An In Vitro Study of Different Extracts and Fractions of Allium sativum (Garlic): Vascular Reactivity
- A Single Treatment With a Specific Chymase Inhibitor, TY-51184, Prevents Vascular Proliferation in Canine Grafted Veins
- .BETA.2-Adrenergic Receptor-Mediated Histamine H1 Receptor Down-Regulation: Another Possible Advantage of .BETA.2 Agonists in Asthmatic Therapy
- Expression of CYP3A4 mRNA Is Correlated With CYP3A4 Protein Level and Metabolic Activity in Human Liver
95
1 - Perspective in Progress of Cardiovascular Gene Therapy
- A New Paradigm for Diabetes and Obesity: the Hepatic Insulin Sensitizing Substance (HISS) Hypothesis
- Doxorubicine-Congestive Heart Failure-Increased Big Endothelin-1 Plasma Concentration: Reversal by Amlodipine, Losartan, and Gastric Pentadecapeptide BPC157 in Rat and Mouse
- The Effects of K+ Channels Modulators Terikalant and Glibenclamide on Membrane Potential Changes Induced by Hypotonic Challenge of Guinea Pig Ventricular Myocytes
- .ALPHA.-Mangostin Induces Ca2+-ATPase-Dependent Apoptosis via Mitochondrial Pathway in PC12 Cells
- Ephedrae herba in Mao-Bushi-Saishin-To Inhibits IgE-Mediated Histamine Release and Increases cAMP Content in RBL-2H3 Cells
- Effects of Nonpeptide and Selective V1 and V2 Antagonists on Blood Pressure Short-Term Variability in Spontaneously Hypertensive Rats
- Aminoguanidine Protects Against Intracranial Hypertension and Cerebral Ischemic Injury in Experimental Heatstroke
- CD14 Glycoprotein Expressed in Vascular Smooth Muscle Cells
- Essential Role of the Interstitial Cells of Cajal in Nitric Oxide-Mediated Relaxation of Longitudinal Muscle of the Mouse Ileum
- Identification of Endogenous Surrogate Ligands for Human P2Y Receptors Through an In Silico Search
- Noxious Stimuli Evoke a Biphasic Flexor Reflex Composed of A.DELTA.-Fiber-Mediated Short-Latency and C-Fiber-Mediated Long-Latency Withdrawal Movements in Mice
- Mechanism of Action by Which Aspirin Alleviates Detrusor Hyperactivity in Rats
- N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina
- Characterization of Intrinsic Sympathomimetic Activity of Carteolol in Rat Cardiovascular Preparations
- Calcineurin Contributes to the Enhancing Effect of Adenosine on Nerve Growth Factor-Induced Neurite Outgrowth via the Decreased Duration of p38 Mitogen-Activated Protein Kinase Phosphorylation
- Changes in Blood Viscosity With Mucopolysaccharide Polysulfate
- T-588, a Cognitive Enhancer, Protects Against Sodium Nitroprusside-Induced Toxicity in Cultured Astrocytes
2 - Proof of the Mysterious Efficacy of Ginseng: Basic and Clinical Trials: Suppression of Adrenal Medullary Function In Vitro by Ginseng
- Proof of the Mysterious Efficacy of Ginseng: Basic and Clinical Trials: Effects of Red Ginseng on Learning and Memory Deficits in an Animal Model of Amnesia
- Proof of the Mysterious Efficacy of Ginseng: Basic and Clinical Trials: Metabolic Activation of Ginsenoside: Deglycosylation by Intestinal Bacteria and Esterification With Fatty Acid
- Proof of the Mysterious Efficacy of Ginseng: Basic and Clinical Trials: Clinical Effects of Medical Ginseng, Korean Red Ginseng: Specifically, Its Anti-stress Action for Prevention of Disease
- A Comparative Pharmacology Study Between the Intracolonic and Oral Routes of 5-FU Administration in a Colon Cancer-Bearing Yoshida Sarcoma Rat Model
- P2Y Receptor-Mediated Ca2+ Signaling Increases Human Vascular Endothelial Cell Permeability
- Antinociceptive Effects of Sodium Channel-Blocking Agents on Acute Pain in Mice
- Hypotonic Stress Increases Efficacy of Rilmakalim, but Not Pinacidil, to Activate ATP-Sensitive K+ Current in Guinea Pig Ventricular Myocytes
- Cardioprotective Effect of SEA0400, a Selective Inhibitor of the Na+/Ca2+ Exchanger, on Myocardial Ischemia-Reperfusion Injury in Rats
- Phospholipase C Involvement in Activation of the Muscarinic Receptor-Operated Cationic Current in Guinea Pig Ileal Smooth Muscle Cells
- Hyperactivity of Endoplasmic Reticulum Associated Exocytosis Mechanism Contributes to Acute Phencyclidine Intoxication
- Increases in Serum Nitrite and Nitrate of a Few-Fold Adversely Affect the Outcome of Pregnancy in Rats
- Development of a Halothane-Adrenaline Arrhythmia Model Using In Vivo Guinea Pigs
- Inhibition of .ALPHA.1E Ca2+ Channels by Carbonic Anhydrase Inhibitors
- Acidic Oligosaccharide Sugar Chain, a Marine-Derived Acidic Oligosaccharide, Inhibits the Cytotoxicity and Aggregation of Amyloid Beta Protein
- Protective Effects of Astragalus Saponin I on Early Stage of Diabetic Nephropathy in Rats
- p38 Mitogen-Activated Protein Kinase Regulates Vasoconstriction in Spontaneously Hypertensive Rats
- Dracorhodin Perchlorate Induces Apoptosis via Activation of Caspases and Generation of Reactive Oxygen Species
- Enhancement of Sphingosine 1-Phosphate-Induced Phospholipase C Activation During G0-G1 Transition in Rat Hepatocytes
- Effects of Combination Treatment With Dipeptidyl Peptidase IV Inhibitor and Sulfonylurea on Glucose Levels in Rats
- Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury
3 - On the Mechanism of Levosimendan-Induced Dopamine Release in the Striatum of Freely Moving Rats
- Doxazosin Effects on Cholinergic and Adrenergic Responses in Rat Isolated Detrusor Smooth Muscle Preparations From Obstructed Bladder
- Validation of a [3H]Astemizole Binding Assay in HEK293 Cells Expressing HERG K+ Channels
- Phosphodiesterase Type IV Inhibitors Prevent Ischemia-Reperfusion-Induced Gastric Injury in Rats
- Failure of Repeated Electroconvulsive Shock Treatment on 5-HT4-Receptor-Mediated Depolarization Due To Protein Kinase A System in Young Rat Hippocampal CA1 Neurons
- Effects of Norepinephrine and Cardiotrophin-1 on Phospholipase D Activity and Incorporation of Myristic Acid Into Phosphatidylcholine in Rat Heart
- Effects of Mannitol on Ischemia-Induced Degeneration in Rat Hippocampus
- Expression of iNOS mRNA and Inhibitory Effect of NO on Uterine Contractile Activity in Rats Are Determined by Local Rather Than Systemic Factors of Pregnancy
- Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats
- Sevoflurane Inhibition of the Slowly Activating Delayed Rectifier K+ Current in Guinea Pig Ventricular Cells
- Potential Anxiolytic and Antidepressant-Like Activities of SNC80, a Selective .DELTA.-Opioid Agonist, in Behavioral Models in Rodents
- A Pegylated Liposomal Platform: Pharmacokinetics, Pharmacodynamics, and Toxicity in Mice Using Doxorubicin as a Model Drug
- Captopril Enhances Cardiac Vagal but Not Sympathetic Neurotransmission in Pithed Rats
- Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina
- Effect of Cilnidipine on L- and T-type Calcium Currents in Guinea Pig Ventricle and Action Potential in Rabbit Sinoatrial Node
4 - Involvement of TRPM7 in Cell Growth as a Spontaneously Activated Ca2+ Entry Pathway in Human Retinoblastoma Cells
- Uridine 5'-Triphosphate Stimulates Alveolar Fluid Clearance in the Isolated Rat Lungs
- Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype
- Apafant, a Potent Platelet-Activating Factor Antagonist, Blocks Eosinophil Activation and Is Effective in the Chronic Phase of Experimental Allergic Conjunctivitis in Guinea Pigs
- Vanadate Activates Rho A Translocation in Association With Contracting Effects in Ileal Longitudinal Smooth Muscle of Guinea Pig
- Involvement of Peripheral Mechanism in the Verapamil-Induced Potentiation of Morphine Analgesia in Mice
- Effects of NSAIDs on Bladder Function in Normal and Cystitis Rats: a Comparison Study of Aspirin, Indomethacin, and Ketoprofen
- The Regulation of Human .BETA.-Defensin 2 by the ETS Transcription Factor MEF (Myeloid Elf-1-Like Factor) Is Enhanced by Promyelocytic Leukemia Protein
- Characterization of the Trafficking Pathway of Cystic Fibrosis Transmembrane Conductance Regulator in Baby Hamster Kidney Cells
- Soybean Isoflavones Eliminate Nifedipine-Induced Flushing of Tail Skin in Ovariectomized Mice
- Acetylcholine-Induced Translocation of RhoA in Freshly Isolated Single Smooth Muscle Cells of Rat Bronchi
- Antioxidant Effects of Stereoisomers of N-Acetylcysteine (NAC), L-NAC and D-NAC, on Angiotensin II-Stimulated MAP Kinase Activation and Vascular Smooth Muscle Cell Proliferation
96
1 - Role of Interstitial Cells of Cajal in the Control of Gastric Motility
- Forefront of Na+/Ca2+ Exchanger Studies: Regulation Kinetics of Na+/Ca2+ Exchangers
- Forefront of Na+/Ca2+ Exchanger Studies: Stoichiometry of Cardiac Na+/Ca2+ Exchanger; 3:1 or 4:1?
- Forefront of Na+/Ca2+ Exchanger Studies: Physiology and Molecular Biology of Monovalent Cation Sensitivities in Na+/Ca2+ Exchangers
- Forefront of Na+/Ca2+ Exchanger Studies: Role of Na+/Ca2+ Exchanger-Lessons From Knockout Mice
- Forefront of Na+/Ca2+ Exchanger Studies: Molecular Pharmacology of Na+/Ca2+ Exchange Inhibitors
- Determination of the Effectiveness of Components of the Herbal Medicine Toki-Shakuyaku-San and Fractions of Angelica acutiloba in Improving the Scopolamine-Induced Impairment of Rat's Spatial Cognition in Eight-Armed Radial Maze Test
- Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors
- Pharmacological Characteristics of Rotational Behavior in Hemiparkinsonian Rats Transplanted With Mouse Embryonic Stem Cell-Derived Neurons
- The Post-ischemic Administration of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e), a Novel Calmodulin Antagonist, Prevents Delayed Neuronal Death in Gerbil Hippocampus
- Carbachol-Induced Secretion and Homologous Desensitization in Rat Basophilic Leukemia (RBL-2H3) Cells Transfected With Human m2 Muscarinic Acetylcholine Receptors
- Yogurt Containing Lactobacillus gasseri OLL2716 Exerts Gastroprotective Action Agaisnt Acute Gastric Lesion and Antral Ulcer in Rats
- Gene Expression Profile in Experimental Mesangial Proliferative Glomerulonephritis
2 - Convergence and Divergence, a Concept for Explaining Drug Actions
- Functional Hypophysectomy Simply by Neck-Strangulation in the Rat: Applications for ACTH and LH Assays
- Alternative Splicing of Human Telomerase Reverse Transcriptase May Not Be Involved in Telomerase Regulation During all-trans-Retinoic Acid-Induced HL-60 Cell Differentiation
- Inhibition Mechanism of Gosha-jinki-gan on the Micturition Reflex in Rats
- Tetrahydrobiopterin Uptake in Supplemental Administration: Elevation of Tissue Tetrahydrobiopterin in Mice Following Uptake of the Exogenously Oxidized Product 7,8-Dihydrobiopterin and Subsequent Reduction by an Anti-folate-Sensitive Process
- Implication of Peroxisome Proliferator-Activated Receptor .GAMMA. and Proinflammatory Cytokines in Gastric Carcinogenesis: Link to Helicobacter pylori-Infection
- Effect of a Selective Inhibitor of Secretory Phospholipase A2, S-5920/LY315920Na, on Experimental Acute Pancreatitis in Rats
- Cytochrome c Release From Oridonin-Treated Apoptotic A375-S2 Cells Is Dependent on p53 and Extracellular Signal-Regulated Kinase Activation
- RNA Editing and Short Variant of Serotonin 2C Receptor mRNA in Neuronally Differentiated NG108-15 Cells
- Role of Corticotropin-Releasing Factor Receptor Type 2.BETA. in Urocortin-Induced Vasodilation of Rat Aortas
- Prior Antagonism of Endothelin-1A Receptors Alleviates Circulatory Shock and Cerebral Ischemia During Rat Heatstroke
- An S-Nitrosylated Hemoglobin Derivative Protects the Rat Hippocampus From Ischemia-Induced Long-Term Potentiation Impairment With a Time Window
- Differential Inotropic Effects of Endothelin-1, Angiotensin II, and Phenylephrine Induced by Crosstalk With cAMP-Mediated Signaling Process in Dog Ventricular Myocardium
- Angiogenesis In Vitro: Vascular Tube Formation From the Differentiation of Neural Stem Cells
- Cardiovascular Effects of an L/N-type Ca2+ Channel Blocker Cilnidipine Assessed in the Chronic Atrioventricular Conduction Block Dogs
- Nitric Oxide Modulation of the Spontaneous Firing of Rat Medial Vestibular Nuclear Neurons
3 - Anti-inflammatory Plant Flavonoids and Cellular Action Mechanisms
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Preface
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Water Channel Aquaporin-2 of Kidney Collecting Duct Cells
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Structure and Function of Aquaporins
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Aquaporins in the Brain
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: The Translocation of Aquaporin-5 From Lipid Rafts to the Apical Plasma Membranes of Parotid Glands of Normal Rats and the Impairment of It in Diabetic or Aged Rats
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Aquaporin Superfamily (Superaquaporins): Expansion of Aquaporins Restricted to Multicellular Organisms
- Effect of Mexiletine on Fenvalerate-Induced Nociceptive Response in Diabetic Mice
- Role of K+ Channels in M2 Muscarinic Receptor-Mediated Inhibition of Noradrenaline Release From the Rat Stomach
- Inhibitory Effect of Antituberculosis Drugs on Human Cytochrome P450-Mediated Activities
- Diphenidol Has No Actual Broad Antiemetic Activity in Dogs and Ferrets
- Oxazolone-Induced Colitis in BALB/C Mice: a New Method to Evaluate the Efficacy of Therapeutic Agents for Ulcerative Colitis
- Effects of Methanol Extract of Uncariae Ramulus et Uncus on Ibotenic Acid-Induced Amnesia in the Rat
- Expression of Cytosolic Phospholipase A2.ALPHA. in Murine C12 Cells, a Variant of L929 Cells, Induces Arachidonic Acid Release in Response to Phorbol Myristate Acetate and Ca2+ Ionophores, but Not to Tumor Necrosis Factor-.ALPHA.
- Biochemical Properties of a Bushmaster Snake Venom Serine Proteinase (LV-Ka), and Its Kinin Releasing Activity Evaluated in Rat Mesenteric Arterial Rings
- Effects of a Selective Inhibitor of Inducible Nitric Oxide Synthase, ONO-1714, on Experimental Hemodialysis-Related Hypotension in Renal Dysfunctional Dogs
4 - Trace Elements and Electrolytes Homeostasis and Their Relation to Antioxidant Enzyme Activity in Brain Hyperexcitability of Epileptic Patients
- New Perspectives in the Studies on Endocannabinoid and Cannabis: Abnormal Behaviors Associate With CB1 Cannabinoid Receptor and Development of Therapeutic Application
- New Perspectives in the Studies on Endocannabinoid and Cannabis: 2-Arachidonoylglycerol as a Possible Novel Mediator of Inflammation
- New Perspectives in the Studies on Endocannabinoid and Cannabis: Cannabinoid Receptors and Schizophrenia
- New Perspectives in the Studies on Endocannabinoid and Cannabis: A Role for the Endocannabinoid-Arachidonic Acid Pathway in Drug Reward and Long-Lasting Relapse to Drug Taking
- Malfunction of Vascular Control in Lifestyle-Related Diseases: Distribution of Adrenomedullin-Containing Perivascular Nerves and Its Alteration in Hypertension
- Malfunction of Vascular Control in Lifestyle-Related Diseases: Formation of Systemic Hemoglobin-Nitric Oxide Complex (HbNO) From Dietary Nitrite
- Malfunction of Vascular Control in Lifestyle-Related Diseases: Mechanisms Underlying Endothelial Dysfunction in the Insulin-Resistant State
- Malfunction of Vascular Control in Lifestyle-Related Diseases: Oxidative Stress of Angiotensin II-induced Hypertension: Mitogen-Activated Protein Kinases and Blood Pressure Regulation
- Malfunction of Vascular Control in Lifestyle-Related Diseases: Endothelial Nitric Oxide (NO) Synthase/NO System in Atherosclerosis
- Puerarin Acts Through Brain Serotonergic Mechanisms to Induce Thermal Effects
- Different Effects of Pueraria mirifica, a Herb Containing Phytoestrogens, on LH and FSH Secretion in Gonadectomized Female and Male Rats
- Electropharmacological Effects of a Spironolactone Derivative, Potassium Canrenoate, Assessed in the Halothane-Anesthetized Canine Model
- GABAB Receptors Do Not Mediate the Inhibitory Actions of Gabapentin on the Spinal Reflex in Rats
- Combined Effects of Psychostimulants and Morphine on Locomotor Activity in Mice
- Effects of Dopamine- and Serotonin-Related Compounds on Methamphetamine-Induced Self-Injurious Behavior in Mice
- Blood Levels of Trace Elements, Electrolytes, and Oxidative Stress/Antioxidant Systems in Epileptic Patients
- Homologous and Heterologous Phosphorylations of Human Histamine H1 Receptor in Intact Cells
- Role of the Interstitial Cells Distributed in the Myenteric Plexus in Neural Reflexes in the Mouse Ileum
- NG-Nitro-L-arginine Methyl Ester-Induced Potentiaton of the Effect of Aminophylline on Rat Diaphragm: the Role of Extracellular Calcium
- The R(-)-Enantiomer of Efonidipine Blocks T-type but Not L-type Calcium Current in Guinea Pig Ventricular Myocardium
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