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List of Jounal Titles
A to Z index of Journal Title. Choose a letter.
Xenobiotic Metabolism and Disposition
15
- Pharmacogenomics. From Basic Science to Clinical Application.
- Structural organization and characterization of the regulatory element of human carboxylesterase gene.
- Induction of Xanthine Oxidase by TCDD.
- Characterization of Cytochrome P4502D6 Variants Expressed in Yeast Cells.
- Relationships Between Genetic Polymorphisms in CYP2D6 and CYP2E1 Genes and Liver Microsomal Drug Oxidation Activities. Studies with 39 Japanese and 45 Caucasians.
- CYP2B Gene Structures and Induction Mechanism: Comparative Studies Using Guinea Pigs with Low Inducibility and Mutant Rats That Lack Responce to Phenobarbital-mediated Induction.
- Molecular Mechanism of Human CYP3A4 Induction: In Vivo Analysis of CYP3A4 Induction by Use of Adenovirous Expression Vector.
- Transcriptional Regulation of the CYP2C12 Gene in Female Rats.
- Genetic Polymorphism of Drug Transporters.
- Role of Renal Organic Anion Transporters, OAT-K1 and OAT-K2, in the Urinary Excretion of Anionic drugs.
- LST-2, a human liver-specific organic anion transporter determine smethotrexate sensitivity in the gastrointestinal cancers.
- Role of Transporter and Metabolic Enzyme in Intestinal Drug Absorption.
- Transports of Excitatory and Inhibitory Neurotransmitters Across the Blood-brain Barrier.
- Transport Mechanism of Basic Fibroblast Growth Factor(bFGF) Through the Blood-brain Barrier.
- Substrate Recognition/Transport Mechanism of Rat Multidrug Resistance-associated Protein 2.
- Competitive Displacement of Serum Protein Binding to Regulate Pharmacokinetics of a Corebral Blood Flow Radiopharmaceutical.
- Relationship Between Physicochemical Characteristics, Distribution of DNA-cationic Liposome Complexes and Their Gene Expression, and Application to Gene therapy.
- Stereoselective Pharmacokinetics and Vasodilating Effect of Organic Nitrates.
- Stereospecific Metabolism of (.ALPHA.-Bromoisovaleryl)Urea in Rats in vivo.
- Development and Application of the Strategy for the Quantitative Prediction of Drug-Induced Parkinsonism.
- Prediction of in vivo Human Hepatic Clearance in Drug Discovery.
- Topology Analysis of Drug Binding Sites on Human Serum Albumin Using Site-Directed Mutagenesis.
- Mechanisms Underlying Renal Tubular Acidosis and Albuminuria Induced by Cisplatin.
- Troglitazone Metabolism and Cytotoxic Effets.
- Involvement of Cytokines in Acetaminophen Hepatotoxicity.
- Happy Research Life Supported by Many Peoples.
- Science for the Extrapolation of Pharmacokinetic Properties to Human in the New Millennium Entering the Paradigm Shift of Drug Discovery and Development.
- Pharmacokinetic Control Based on Pharmacogenetic Information for Drug Transportersand Its Application to Optimizing Drug Therapy.
- Role of Glutathione Transferases in the Metabolism of Endobiotics and Xenobiotics.
- The Role of UDP-Glucuronosyltransferases and Transporters in Endo- and Xeno-biotic Glucuronidation and Excretion.
- Nicotine: Metabolic Pathways and Metabolic Mysteries.
- From the Aspect of Drug Development.
- Application of Cassette Dosing for Evaluating the Pharmacokinetic Profiles of Drug Candidates at Lead Optimization Stage.
- The Use of Surgical Models for the Evaluation of Potential Drug Candidates.
- In Vitro Metabolism of NK-104. (2). A New Inhibitor of HMG-CoA Reductase.
- Enzymology of the Human Hepatic Metabolism of Ciclesonide(B9207-015).
1
- Scavenger Receptor-Mediated Uptake of Fractionated [3H]Heparin in Rat Peritoneal Macrophages.
- New Nomenclature of Human ABC Transporter Genes.
- The Metabolism and Toxicity of .ALPHA.,.BETA.-Unsaturated Aldehydes. The Role of Glutathione S-Transferase.
- Study of Human P450 Enzymes in Drug Oxidations using Recombinant P450s and Human Liver Microsomes.
- Interindividual Variations in Xenobiotic-Oxidizing P450 Activities in Humans.
- Oxidation of Optically Active Substrates by Human and Rat CYP2D Enzymes.
- Detection of Cytochrome P450 Induction. Development of Non-Invasive Assay.
- Molecular Mechanisms of CYP3A Gene Transactivations by Chemicals and their Species Differences.
- The Study on Genetic Polymorphism of CYP2A6.
2
- Disposition and Metabolism of the Oral Antidiabetic Drug Troglitazone in Monkeys.
- Identitication of Cytochrome P450 Involved in the Metabolism of Donepezil and In Vitro Drug Interaction Study in Human Liver Microsomes.
- Study on Regulation of Pharmacokinetics of Drugs Based on the Membrane Transport Mechanisms.
- An Active Metabolite ofMorphine and the Responsible Glucuronosyltransferase for its Formation.
- Studies on Drug Metabolism by Gas Chromatography-Mass Spectrometry and it's Related Technique.
- Analysis of Drug Efflux Systems in the Blood-brain and Blood-cerebrospinal Fluid Barriers.
- Current Status and Critical Issues on the Investigation of Small Intestinal Metabolism.
- The Study on CYP2D6*10 In Vivo and In Vitro.
- Genetic Polymorphism of Human Tissue Phenol Sulfotransferases.
- Identification and Characterization of Human Liver-Specific Organic Anion Transporter LST-1.
- Molecular and Functional Characterization of Carnitine/Organic Cation Transporter OCTN Family in Human and Mouse.
- Assessment of Tear Concentrations on TDM. Pharmacokinetic Studies of Theophylline and Valproic Acid in Plasma, Cerebrospinal Fluid and Tear.
- Prediction of Oral Absorption of Cephalosporins in Humans.
- Assessment of Bioavailability using Pharmacological Responses.
3
- Carrier-Mediated Uptake of Cerivastatin in Primary Cultured Rat Hepatocytes.
- Mechanism-based Preclinical Approaches for the Evaluation of Drug-Drug Interactions.
- Quantitative Prediction of Drug Interation Involving Metabolism and Transport in the Liver.
- The Imformation on Clinical Important Drug Interactions.
- Drug Interaction Working Group. HAB Database.
- Drug Interaction Working Group. Japan Pharmaceutical Manufacturers Association.
- A Possible Mechanism of Lethal Interactions of the New Antiviral Drug, Sorivudine, with 5-Fluorouracil Prodrugs and Clinical Problems on Anti-cancer Chemotherapy.
- Effectiveness and its Prediction of Charcoal Hemoperfusion Treatment in Drug Overdose. A Guideline Based on the Protein Binding Percentage of the Drug.
- Pharmacokinetic Analysis of Insulin-mimetic Vanadyl Complexes in Rats. Metallokinetic Analysis by BCM-ESR Method and Neutron Activation Analysis.
4
- Distribution (Autoradiography) of a New Synthetic Antibacterial Agent OPB-2045 in Rats.
- Studies on the Metabolic Fate of TA-510, a Hepatic Anti-inflammatory Agent. (1). Blood Concentration, Distribution and Excretion in Bats and Dogs.
- Studies on the Metabolic Fate of TA-510, a Hepatic Anti-inflammatory Agent. (II). Metabolism alter Oral Administration to Rats. Dogs and Human.
- Studies on the Metabolic Fate of TA-510, a Hepatic Anti-inflammatory Agent. (III).Ildentitication of TA-510 Reductase in Human Liver.
- Significance and Possibilities of Pharmacokinetic/Pharmacodynamic (PK/PD) Analysis.
- Population Analysis of the Pharmacokinetic Variability in Children and the Elderly.
- Statistical Analyses in Clinical PPK/PD Studies. Bridging Studies using NONMEM.
- Clinical Study Design considering Pharmacokinetics.
- Global Drug Development Based on ICH-E5 Guideline.
- Quantitative Prediction of the Pharmacological Effects and Averse Reactions Based on Pharmacokinetics and Pharmacodynamics.
- Summary Report of a FDA/SOT Meeting in USA. Principally PK-Based Risk Assesment.
5
- Pharmacokinetic Study of Capecitabine in Monkeys and Mice. Species Diffrences in Distribution of the Enzymes Responsible for its Activation to 5-FU.
- Practical Application of Pharmacokinetic-Pharmacodynamic Modeling.
- Clinical Significance of the Changing of Plasma Protein Binding of Drug.
- Reflection of Pharmacokinetic study on Package Insert.
- Critical Views on Post-marketing Clinical Trials in Japan.
- Mechanism-based Pharmacokinetics and Pharacodynamics. Future Perspectives.
6
- Individual Variations in the Elimination Process of Fentanyl in Patients.
- Validation Studies of Radioluminography. III. Examination of the Uniformity in .BETA.-Ray Sensitivity.
- Validation Studies of Radioluminography. IV. Confirmation of the Uniformities in Sensitivity of BAS and IP by Use of a 14C Test Radiation Source.
Supplement
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