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List of Jounal Titles
A to Z index of Journal Title. Choose a letter.
Xenobiotic Metabolism and Disposition
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- Genetically Engineered Bacterial Cells Co-expressing Human Cytochrome P450 with NADPH-cytochrome P450 Reductase: Prediction of Metabolism and Toxicity of Drugs in Humans.
- The Potential for an Interaction between MRP2 (ABCC2) and Various Therapeutic Agents: Probenecid as a Candidate Inhibitor of the Biliary Excretion of Irinotecan Metabolites.
- Evaluation of Blood-Brain Barrier Transporters by Co-culture of Brain Capillary Endothelial Cells with Astrocytes.
- Selective Suppressions of Human CYP3A Forms, CYP3A5 and CYP3A7, by Troglitazone in HepG2 Cells.
- Activities of Cytochrome P450 Enzymes in Liver and Kidney Microsomes from Systemic Carnitine Deficiency Mice with a Gene Mutation of Carnitine/Organic Cation Transporter.
- Induction of Cytochrome P450 1A1 in Mice by Repeated Oral Administration of Propranolol.
- Studies on the Metabolic Fate of M17055, a Novel Diuretic (4): Species Difference in Metabolic Pathway and Identification of Human CYP Isoform Responsible for the Metabolism of M17055.
- Comparative Analysis of In Vitro and In Vivo Pharmacokinetic Parameters Related to Individual Variability of GTS-21 in Canine.
- Clarification of the Mechanism of Structural Change Induced by Reoxygenation following the Induction of Lipid Peroxidation in Caco-2 Cell Monolayers.
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- Novel Mutations of the CYP2A6 Gene in a Thai Population with Lowered Capacity of Coumarin 7-Hydroxylation.
- A Major Genotype in UDP-glucuronosyltransferase 2B15.
- Drug Transporters: Their Role and Importance in the Selection and Development of New Drugs.
- Contribution of CYP4A8 to the Formation of 20-Hydroxyeicosatetraenoic Acid from Arachidonic Acid in Rat Kidney.
- Molecular Cloning of Monkey CYP2C43 cDNA and Expression in Yeast.
- Rat Renal Organic Anion Transporter rOAT1 Mediates Transport of Urinary-Excreted Cephalosporins, but not of Bilary-Excreted Cefoperazone.
- Does ABCG2 Need a Heterodimer Partner? Expression and Functional Evaluation of ABCG2 (Arg 482).
- Effect of Co-administration of Cationic Macromolecules on the In Vivo Disposition and In situ Renal Disposition Characteristics of rhIL-11.
- Separation and Determination of Diastereomeric Flurbiprofen Acyl Glucuronides in Human Urine by LC/ESI-MS with a Simple Column-Switching Technique.
- CYP3A4 Gene Polymorphisms Influence Testosterone 6.BETA.-hydroxylation.
- Determination of CYP2D6 Gene Alleles by the CYP450 Probe Array Using the Affymetrix GeneChip System: Comparison with Sequencing Results.
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- Genetic Polymorphism of Human Cytochrome P450 Involved in Drug Metabolism.
- Simultaneous Assessment of the In Vivo Amount of CYP1A2 and CYP3A2 by the PKCYP-test Using Theophylline in Rats.
- Metabolism of Selegiline Hydrochloride, a Selective Monoamine B-type Inhibitor, in Human Liver Microsomes.
- A Mutation in the Flavin-containing Monooxygenase 3 Gene and its Effects on Catalytic Activity for N-oxidation of Trimethylamine In Vitro.
- Studies on the Metabolic Fate of M17055, a Novel Diuretic (5): Pharmacokinetics and Pharmacodynamics of Unchanged Drug in Rat and Dog After Intravenous Administration of M17055.
- Sulfation of Environmental Estrogens by Cytosolic Human Sulfotransferases.
- Identification of Inhibitory Component in Cinnamon. O-Methoxycinnamaldehyde Inhibits CYP1A2 and CYP2E1.
- Muscle Distribution of Antimicrobial Agents after a Single Intravenous Administration to Rats.
- Interaction of Endogenous Compounds in Human and Rat Urine with P-glycoprotein.
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- Transporter-mediated Drug Interactions.
- Effects of Single and Repeated Treatment with Itraconazole on the Pharmacokinetics of Midazolam in Rats.
- Evaluation of Gastrointestinal Transit Characteristics of Oral Patch Preparation Using Caffeine as a Model Drug in Human Volunteers.
- Nonlinear Pharmacokinetics of Aprindine in Guinea Pigs.
- Characterization of Ligand Binding Sites on the .ALPHA.1-Acid Glycoprotein in Humans, Bovines and Dogs.
- Analysis and Prediction of Absorption Behavior for Theophylline Orally Administered as Powders Based on Gastrointestinal-transit-Absorption (Gita) Model.
- Strategy for Structure Elucidation of Drug Metabolites Derived from Protonated Molecules and (MS)n Fragmentation of Zotepine, Tiaramide and their Metabolites.
- Metallokinetic Study of Zinc in the Blood of Normal Rats Given Insulinomimetic Zinc(II) Complexes and Improvement of Diabetes Mellitus in Type 2 Diabetic GK Rats by their Oral Administration.
- Molecular Characterization of Two Monkey Dihydrodiol Dehydrogenases.
- Genotyping of the N-acetyltransferase2 Polymorphism in the Prediction of Adverse Drug Reactions to Isoniazid in Japanese Patients.
- Lack of Interaction Between Cefdinir and Calcium Polycarbophil: In vitro and In vivo Studies.
- mRNA Expression and Amino Acid Transport Characteristics of Cultured Human Brain Microvascular Endothelial Cells (hBME).
- Five Novel Single Nucleotide Polymorphisms in the CYP2C8 Gene, One of which Induces a Frame-shift.
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- Novel single nucleotide polymorphisms in the CYP2D6 gene associated with CYP2D6*2 and/or CYP2D6*10 alleles.
- Polymorphism of MDR1 Gene in Healthy Japanese Subjects: A Novel SNP with an Amino Acid Substitution (Glu108Lys).
- Twenty One Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2A6 Gene in Japanese and Caucasians.
- Three novel single nucleotide polymorphisms in UGT1A10.
- Safety Evaluation and Drug Development based on Biological Fate of Drugs. Efforts Made to Overcome Drug Interaction in Drug Development.
- Application of In Vivo Brain Microdialysis to the Study of Blood-Brain Barrier Transport of Drugs.
- New Methods to Evaluate Intestinal Drug Absorption Mediated by Oligopeptide Transporter from In vitro Study using Caco-2 Cells.
- Evidence for Singlet Oxygen Involvement in Rat and Human Cytochrome P450-dependent Substrate Oxidations.
- Species Difference in Nisoldipine Oxidation Activity in the Small Intestine.
- Application of Microtiter Plate Assay to Evaluate Inhibitory Effects of Various Compounds on Nine Cytochrome P450 Isoforms and to Estimate their Inhibition Patterns.
- Metabolic Fate of Pitavastatin, a New Inhibitor of HMG-CoA Reductase. Effect of cMOAT Deficiency on Hepatobiliary Excretion in Rats and of mdr1a/b Gene Disruption on Tissue Distribution in Mice.
- Formation of a Structurally Novel, Serial Diglucuronide of 4-Hydroxybiphenyl by Further Glucuronidation of a Monoglucuronide in Dog Liver Microsomes.
- Effects of St John's Wort and Hypericin on Cytotoxicity of Anticancer Drugs.
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- Eleven Novel Single Nucleotide Polymorphisms in the NR1I2(PXR) Gene, Four of which Induce Non-synonymous Amino Acid Alterations.
- Twelve Novel Single Nucleotide Polymorphisms in ABCB1/MDR1 among Japanese Patients with Ventricular Tachycardia who were Administered Amiodarone.
- CYPalleles: A Web Page for Nomenclature of Human Cytochrome P450 Alleles.
- Kinetic Impact of Presystemic Intestinal Metabolism on Drug Absorption: Experiment and Data Analysis for the Prediction of In Vivo Absorption from In Vitro Data.
- Species Differences in the Metabolism of (+)- and (-)-Limonenes and their Metabolites, Carveols and Carvones, by Cytochrome P450 Enzymes in Liver Microsomes of Mice, Rats, Guinea Pigs, Rabbits, Dogs, Monkeys, and Humans.
- Major Cytochrome P450 Enzymes Responsible for Microsomal Aldehyde Oxygenation of 11-Oxo-.DELTA.8-tetrahydrocannabinol and 9-Anthraldehyde in Human Liver.
- Effects of Serum Albumin and Liver Cytosol on CYP2C9- and CYP3A4-mediated Drug Metabolism.
- Determination of a Novel Haplotype of .BETA.2-adrenergic Receptor in the Japanese Population by the Combination of the Electronic Microchip Assay Using the NanoChip System with Allelespecific PCR.
- Plasma Retinol Binding Protein for Monitoring the Acetaminophen-induced Hepatotoxicity.
- Metabolic Extraction of Nifedipine during Absorption from the Rat Small Intestine.
- Involvement of Specific Transport System of Renal Basolateral Membranes in Distribution of Nicotine in Rats.
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